Nonomuraea turkmeniaca

General Information

Nonomuraea turkmeniaca is a fascinating microorganism belonging to the genus Nonomuraea, which is part of the family Streptomycetaceae. This genus is known for its complex secondary metabolism, making it a rich source of bioactive compounds. One of the most intriguing aspects of Nonomuraea turkmeniaca is its ability to produce novel antibiotics and other pharmacologically active substances. This characteristic makes it a valuable subject for research in the field of natural product discovery and drug development. Nonomuraea turkmeniaca has been isolated from soil, which is a common habitat for many actinobacteria known for their prolific production of secondary metabolites. The soil environment provides a competitive landscape that drives the evolution of unique biochemical pathways in these microorganisms. The potential of Nonomuraea turkmeniaca to produce new antibiotics is particularly significant in the context of rising antibiotic resistance, as there is a continuous need for new antimicrobial agents to combat resistant pathogens. Additionally, the genus Nonomuraea is characterized by its complex and diverse morphological structures, which can include filamentous growth and the formation of spore chains. These features not only contribute to its ecological success but also offer interesting avenues for studying microbial development and differentiation. In summary, Nonomuraea turkmeniaca stands out due to its remarkable capacity for secondary metabolite production, making it a key organism for biotechnological applications and pharmaceutical research. Its unique biochemical capabilities and ecological adaptations provide a wealth of opportunities for scientific exploration and potential therapeutic advancements.

Nonomuraea turkmeniaca is a fascinating actinobacterium that was first isolated from soil samples in Turkmenistan. This organism is particularly notable for its ability to produce a variety of bioactive compounds, which have garnered interest in the fields of pharmaceuticals and biotechnology. One of the most remarkable aspects of Nonomuraea turkmeniaca is its potential for antibiotic production, making it a valuable candidate for the discovery of new antimicrobial agents. The unique metabolic pathways of this species allow it to synthesize secondary metabolites that may exhibit activity against resistant strains of bacteria, which is a pressing concern in modern medicine. In addition to its antibiotic properties, Nonomuraea turkmeniaca is also known for its ability to degrade complex organic compounds, which positions it as a potential player in bioremediation efforts. This capability to break down pollutants can be harnessed to clean up contaminated environments, showcasing the organism's ecological importance. Furthermore, the genetic and biochemical diversity of Nonomuraea turkmeniaca provides a rich area for research into microbial ecology and evolution. Its adaptability to various environmental conditions makes it an interesting subject for studies on microbial resilience and survival strategies. Overall, Nonomuraea turkmeniaca stands out not only for its unique biochemical capabilities but also for its potential applications in health and environmental sciences.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Streptosporangiales

Family: Streptosporangiaceae

Genus: Nonomuraea

Species: Nonomuraea turkmeniaca

NCBI ID

103838

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/005/889/735/GCF_005889735.1_ASM588973v1

File for sequence-based predictions:
GCF_005889735.1_ASM588973v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The actinomycete Nonomuraea turkmeniaca is a notable microorganism primarily recognized for its potential in the field of antibiotic production. This organism has been isolated from soil samples in Turkmenistan and has shown promise in producing bioactive compounds that may have therapeutic applications. One of the key clinical implications of Nonomuraea turkmeniaca is its ability to synthesize antimicrobial agents, which could be crucial in the fight against multidrug-resistant pathogens. In terms of pathogenicity, there is limited documentation regarding direct infections in humans; however, the potential for its metabolites to be developed into novel antibiotics highlights its relevance in addressing the growing concern of antimicrobial resistance (AMR). The unique biosynthetic pathways of Nonomuraea turkmeniaca may provide insights into new drug discovery, particularly in the development of therapeutics that can circumvent existing resistance mechanisms. Furthermore, the organism's interaction with the human microbiome is an area of interest, as its metabolites could potentially influence immune responses or serve as probiotics in certain contexts. While there are no well-documented outbreaks or infections directly associated with Nonomuraea turkmeniaca, its role in producing bioactive compounds positions it as a significant player in the ongoing search for new antimicrobial agents and therapeutic strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Nonomuraea turkmeniaca is a species of actinobacteria that is primarily found in arid and semi-arid environments, particularly in regions characterized by sandy soils and saline conditions. This microorganism thrives in these challenging habitats, showcasing its remarkable ability to adapt to extreme conditions. Its presence is often associated with desert ecosystems, where it plays a crucial role in the degradation of organic matter and nutrient cycling. In these biomes, Nonomuraea turkmeniaca contributes to the breakdown of complex organic compounds, facilitating the release of nutrients back into the soil. This process is vital for maintaining soil fertility and supporting plant life in otherwise nutrient-poor environments. The organism's metabolic capabilities allow it to utilize a variety of substrates, which enhances its survival in nutrient-limited habitats. Additionally, Nonomuraea turkmeniaca may engage in symbiotic relationships with other microorganisms, such as fungi and plants, aiding in the establishment of microbial communities that enhance soil health. Its ability to produce secondary metabolites also suggests potential roles in biocontrol and antibiotic production, which can influence the dynamics of microbial populations in its habitat. Overall, Nonomuraea turkmeniaca exemplifies the resilience and ecological significance of microorganisms in arid biomes, highlighting their essential contributions to ecosystem functioning and stability.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Nonomuraea turkmeniaca has shown significant potential in various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This actinobacterium is known for its ability to produce a range of bioactive compounds, including antibiotics and other secondary metabolites, which are crucial in the development of new pharmaceuticals. Its role in fermentation processes allows for the extraction and production of these valuable compounds, making it a key player in the pharmaceutical industry. In addition to its pharmaceutical applications, Nonomuraea turkmeniaca has been studied for its capabilities in waste management. The organism exhibits properties that enable it to degrade complex organic materials, which can be harnessed in biodegradation processes. This makes it a candidate for use in bioremediation efforts, where it can help in the breakdown of pollutants and contribute to environmental cleanup. Furthermore, the enzymatic activities of Nonomuraea turkmeniaca are of interest in biotechnology. The enzymes produced by this microorganism can be utilized in various industrial processes, including the production of biofuels. By participating in enzyme production, it can facilitate the conversion of biomass into renewable energy sources, thus contributing to sustainable energy solutions. Overall, Nonomuraea turkmeniaca represents a promising organism for biofuel production, waste treatment, and pharmaceutical development, showcasing its versatility and importance in modern industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	mistralai/mistral-7b-instruct	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	google/gemini-pro	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemma-7b-it	google/gemma-7b-it	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerotolerant ✗	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	false	false	true	true	false	true	true	false	true	true	false	false	true	true	true	true	false	false	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	false	false	true	false	true	false	false	false	false	false	true	true	false	false	false	false	false	false	true	true	true	true	false	false	true	true
Host association	N/A	true	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	false ✗	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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