Streptomyces phaeoluteigriseus

General Information

Streptomyces phaeoluteigriseus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. phaeoluteigriseus is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it an invaluable resource in pharmaceutical research and biotechnology. The genus Streptomyces is well-known for its complex life cycle and filamentous growth, which resembles that of fungi. S. phaeoluteigriseus forms a dense, branched mycelium that can differentiate into spores, contributing to its resilience and adaptability in various environments. Another intriguing aspect of S. phaeoluteigriseus is its soil-dwelling nature, where it plays a crucial role in decomposing organic matter and contributing to soil health. This ecological role underscores its importance in natural nutrient cycling and soil fertility. From a genetic perspective, S. phaeoluteigriseus possesses a large genome with a high G+C content, typical of the Streptomyces genus. This genetic richness provides a vast reservoir of genes that can be harnessed for the discovery of new drugs and industrial enzymes. In summary, Streptomyces phaeoluteigriseus is a microorganism of significant interest due to its prolific production of bioactive compounds, its complex and adaptable life cycle, and its essential role in soil ecosystems. Its genetic potential continues to be a valuable asset in the search for novel therapeutic agents and biotechnological applications.

Streptomyces phaeoluteigriseus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is part of the genus Streptomyces, which is renowned for its prolific secondary metabolite production, including antibiotics, antifungals, and immunosuppressants. What sets S. phaeoluteigriseus apart is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic applications. One of the most interesting aspects of S. phaeoluteigriseus is its ability to produce phaeolutein, a pigment that has been studied for its antioxidant properties. This pigment not only contributes to the organism's distinctive coloration but also has implications for health and nutrition, as antioxidants are known to combat oxidative stress in biological systems. The potential health benefits of compounds derived from S. phaeoluteigriseus make it a subject of interest in nutraceutical research. Additionally, S. phaeoluteigriseus has been isolated from various environments, including soil and decaying plant material, which highlights its ecological role in nutrient cycling and decomposition. This adaptability to diverse habitats underscores its evolutionary success and potential for biotechnological applications, such as bioremediation and sustainable agriculture. In summary, Streptomyces phaeoluteigriseus is not only a model organism for studying secondary metabolite biosynthesis but also a promising source of natural products with significant implications for health and environmental sustainability.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces phaeoluteigriseus

NCBI ID

114686

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/023/923/245/GCA_023923245.1_ASM2392324v1

File for sequence-based predictions:
GCA_023923245.1_ASM2392324v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces phaeoluteigriseus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This microorganism has been studied for its potential in antimicrobial therapy, particularly due to its ability to produce various secondary metabolites that exhibit antibacterial and antifungal properties. One of the notable compounds produced by S. phaeoluteigriseus is phaeolutine, which has shown activity against certain pathogenic bacteria, making it a candidate for further research in the development of new antibiotics to combat antimicrobial resistance. In terms of human health, while S. phaeoluteigriseus is not typically associated with human infections, its relatives in the Streptomyces genus have been implicated in opportunistic infections, particularly in immunocompromised individuals. The organism's ability to produce a variety of enzymes and metabolites may contribute to its pathogenicity in certain contexts, although specific cases involving S. phaeoluteigriseus are limited. Furthermore, the potential use of S. phaeoluteigriseus in probiotics and bioremediation is an area of interest, as its metabolic products may enhance gut health or aid in the degradation of environmental pollutants. However, more research is needed to fully understand its interactions with the human microbiome and its overall impact on human health. Overall, while Streptomyces phaeoluteigriseus is primarily recognized for its role in antibiotic production, its implications in disease associations, immune evasion strategies, and potential therapeutic applications warrant further investigation.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces phaeoluteigriseus is a species of bacterium that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its presence is often linked to the breakdown of complex organic compounds, contributing to nutrient cycling within the soil biome. In particular, S. phaeoluteigriseus is known for its ability to produce a variety of antibiotic compounds, which not only help it compete with other microorganisms but also influence the microbial community structure in its habitat. This characteristic makes it an important player in soil health and plant growth, as it can suppress pathogenic organisms and promote beneficial interactions. Additionally, this bacterium is often found in forest ecosystems, where it colonizes leaf litter and decomposing wood. Here, it engages in symbiotic relationships with fungi and plants, aiding in the breakdown of tough plant materials and enhancing nutrient availability for other organisms in the ecosystem. Overall, Streptomyces phaeoluteigriseus exemplifies the intricate relationships within terrestrial biomes, showcasing its adaptability and essential role in maintaining ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces phaeoluteigriseus is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is renowned for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes, which are crucial in the pharmaceutical industry. For instance, it has been documented to produce compounds that exhibit antimicrobial properties, making it a valuable resource in the development of new antibiotics through fermentation processes. In the realm of biotechnology, Streptomyces phaeoluteigriseus is utilized for its enzymatic activities, particularly in the production of enzymes that can be applied in various industrial processes. These enzymes can facilitate biodegradation of complex organic materials, thus playing a role in waste management by breaking down pollutants and organic waste in environmental applications. Moreover, the organism has potential in biofuel production, where its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes. This capability not only contributes to sustainable energy solutions but also aids in the reduction of waste materials. Overall, Streptomyces phaeoluteigriseus exemplifies the versatility of microorganisms in industrial applications, showcasing its importance in pharmaceutical development, biotechnology, and environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	anthropic/claude-3.5-sonnet	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	google/gemini-pro	google/gemini-pro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openchat/openchat-7b	openchat/openchat-7b
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	true	true	false	true	true	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

Back to Search