Pseudomonas donghuensis

General Information

Pseudomonas donghuensis is a fascinating microorganism that has garnered attention due to its unique metabolic capabilities and potential applications in biocontrol and bioremediation. This bacterium was first isolated from the Donghu Lake in China, which is reflected in its name. One of the most intriguing aspects of P. donghuensis is its ability to produce a variety of secondary metabolites, including antibiotics and siderophores. These compounds not only help the bacterium to thrive in competitive environments by inhibiting the growth of other microorganisms but also make it a promising candidate for agricultural applications, particularly in the development of natural pesticides. Another notable feature of P. donghuensis is its capacity to degrade environmental pollutants. This makes it a valuable organism for bioremediation efforts aimed at cleaning up contaminated sites. The bacterium's enzymatic machinery allows it to break down complex organic compounds, including hydrocarbons and other toxic substances, thereby reducing environmental pollution. From a research perspective, P. donghuensis is also interesting due to its genetic and phenotypic diversity. Studies have shown that this species exhibits a wide range of genetic variations, which contribute to its adaptability and resilience in different environmental conditions. This genetic diversity is a rich resource for scientists looking to understand microbial evolution and adaptation. In summary, Pseudomonas donghuensis stands out for its antibiotic production, biocontrol potential, and bioremediation capabilities, making it a microorganism of significant interest in both applied and fundamental microbiological research.

Pseudomonas donghuensis is a fascinating bacterium that was first isolated from a freshwater lake in China. This organism is particularly interesting due to its biodegradative capabilities, which allow it to break down various environmental pollutants, including aromatic compounds. This characteristic makes Pseudomonas donghuensis a valuable candidate for bioremediation efforts, as it can potentially be used to clean up contaminated environments effectively. Another notable feature of Pseudomonas donghuensis is its ability to produce extracellular enzymes that facilitate the degradation of complex organic materials. This enzymatic activity not only contributes to its ecological role in nutrient cycling but also opens avenues for research into enzyme applications in industrial processes. Furthermore, Pseudomonas donghuensis has been studied for its antimicrobial properties, showing potential against various pathogens. This aspect is particularly relevant in the context of increasing antibiotic resistance, as researchers explore alternative sources for new antimicrobial agents. In summary, Pseudomonas donghuensis stands out due to its environmental significance, biotechnological potential, and antimicrobial properties, making it a subject of interest for both ecological and medical research.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Pseudomonadales

Family: Pseudomonadaceae

Genus: Pseudomonas

Species: Pseudomonas donghuensis

NCBI ID

1163398

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/696/345/GCA_000696345.2_ASM69634v2

File for sequence-based predictions:
GCA_000696345.2_ASM69634v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Pseudomonas donghuensis is a member of the Pseudomonas genus, which is known for its environmental versatility and clinical significance. This organism has been associated with various infections, particularly in immunocompromised patients. Its role in human health is complex, as it can exist as a commensal organism but also has the potential to become pathogenic under certain conditions. Clinical implications of Pseudomonas donghuensis include its association with nosocomial infections, particularly in patients with underlying health issues or those undergoing invasive procedures. The organism has been implicated in respiratory infections, wound infections, and bacteremia, highlighting its pathogenic potential. One of the notable features of Pseudomonas donghuensis is its antimicrobial resistance mechanisms, which are characteristic of many Pseudomonas species. This organism can exhibit resistance to multiple classes of antibiotics, complicating treatment options for infections. The presence of beta-lactamases and other resistance genes contributes to its ability to evade standard antimicrobial therapies, making it a significant concern in clinical settings. In terms of immune evasion, Pseudomonas donghuensis can produce a variety of virulence factors, including exopolysaccharides that help it form biofilms, thereby enhancing its survival in hostile environments and contributing to chronic infections. The ability to form biofilms is particularly problematic in medical devices and chronic wounds, where it can lead to persistent infections that are difficult to eradicate. While Pseudomonas donghuensis is not as widely studied as other Pseudomonas species, its potential for causing disease and its resistance profiles underscore the need for ongoing research and surveillance. Understanding its clinical relevance is crucial for developing effective treatment strategies and managing infections associated with this organism.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Pseudomonas donghuensis is a versatile bacterium commonly found in various habitat types that include both terrestrial and aquatic environments. This microorganism thrives particularly well in freshwater ecosystems, where it plays a crucial role in nutrient cycling and organic matter decomposition. Its ability to degrade a wide range of organic compounds makes it an important player in the biodegradation processes within these habitats. In addition to freshwater environments, Pseudomonas donghuensis has been documented in soil ecosystems, where it contributes to soil health by promoting plant growth through mechanisms such as nitrogen fixation and phosphate solubilization. This bacterium often engages in symbiotic relationships with various plant species, enhancing nutrient availability and improving plant resilience against pathogens. Furthermore, Pseudomonas donghuensis exhibits remarkable environmental adaptability, allowing it to survive in extreme conditions such as high salinity or varying pH levels. This adaptability not only enables it to colonize diverse environments but also positions it as a potential candidate for bioremediation efforts in contaminated sites, where it can help mitigate the effects of pollutants. Overall, Pseudomonas donghuensis is a key organism in its associated biomes, contributing to ecological balance and sustainability through its various interactions and roles within the ecosystem.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Pseudomonas donghuensis has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Pseudomonas donghuensis is utilized for its ability to produce enzymes that can be harnessed in biocatalysis processes. These enzymes are valuable in the production of biofuels, as they can facilitate the breakdown of complex organic materials into simpler compounds that can be fermented into ethanol or other biofuels. In the realm of waste management, Pseudomonas donghuensis has demonstrated capabilities in biodegradation, particularly in the breakdown of pollutants such as hydrocarbons and heavy metals. This makes it a candidate for use in bioremediation strategies aimed at cleaning up contaminated environments, such as oil spills or industrial waste sites. Furthermore, the organism has potential applications in pharmaceutical development. Its metabolic pathways can be exploited for the production of bioactive compounds, which may lead to the discovery of new drugs or therapeutic agents. The ability of Pseudomonas donghuensis to produce secondary metabolites can be particularly useful in this context. Overall, the versatility of Pseudomonas donghuensis in processes such as fermentation, enzyme production, and waste treatment highlights its importance in advancing sustainable industrial practices and developing innovative solutions across multiple sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemma-7b-it	google/gemini-pro-1.5	google/gemini-pro	mistralai/mistral-7b-instruct	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	false ✗	true ✓	false ✗	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	false	true	true	true	true	false	false	false	false	false	true	true	true	true	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	true	true	true	true	true	false	false	false	false	false	false	false	true	true	true	true	false	false	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	spirillum ✗	spirillum ✗

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