Propionibacterium australiense

General Information

Propionibacterium australiense is a fascinating microorganism that belongs to the genus Propionibacterium. This genus is well-known for its role in the production of propionic acid, which is a valuable compound in both the food and pharmaceutical industries. One of the most interesting aspects of P. australiense is its ability to produce propionic acid through the fermentation of sugars and lactate. This metabolic capability makes it an important organism for industrial applications, particularly in the production of Swiss cheese, where propionic acid contributes to the characteristic flavor and the formation of holes in the cheese. Another unique feature of P. australiense is its potential use in bioremediation. The organism has been studied for its ability to degrade various environmental pollutants, making it a candidate for cleaning up contaminated sites. Additionally, P. australiense has been explored for its probiotic properties, as members of the Propionibacterium genus are known to have beneficial effects on gut health. From a research perspective, P. australiense is valuable due to its relatively simple genetic makeup, which allows for easier manipulation and study in laboratory settings. This makes it an excellent model organism for studying bacterial metabolism and gene regulation. Furthermore, the organism's ability to thrive in diverse environments provides insights into microbial adaptability and resilience. In summary, Propionibacterium australiense is a microorganism of significant interest due to its industrial applications, potential in bioremediation, probiotic properties, and value as a model organism in scientific research. Its diverse capabilities and adaptability make it a subject of ongoing study and exploration in various fields of microbiology and biotechnology.

Propionibacterium australiense is a fascinating species of bacteria that belongs to the genus Propionibacterium, which is known for its role in the production of propionic acid and its significance in various fermentation processes. This organism is particularly interesting due to its unique metabolic capabilities, which allow it to thrive in anaerobic environments and contribute to the flavor and texture of certain dairy products, such as cheese. One of the standout features of P. australiense is its ability to produce short-chain fatty acids, which are important for gut health and have been linked to various health benefits in humans. This characteristic makes it a valuable organism for research in the fields of microbiology and nutrition, as scientists explore its potential applications in probiotics and functional foods. Additionally, P. australiense has been studied for its biotechnological potential in the production of bioactive compounds. Its metabolic pathways are of interest for bioproduction processes, where it could be harnessed to create sustainable alternatives to traditional chemical processes. Furthermore, the organism's genetic diversity and adaptability to different environments make it a subject of interest in evolutionary studies, providing insights into microbial evolution and adaptation mechanisms. Overall, Propionibacterium australiense stands out not only for its contributions to food science but also for its potential implications in health and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Propionibacteriales

Family: Propionibacteriaceae

Genus: Propionibacterium

Species: Propionibacterium australiense

NCBI ID

119981

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/900/637/915/GCA_900637915.1_52941_B01

File for sequence-based predictions:
GCA_900637915.1_52941_B01_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Propionibacterium australiense is a member of the genus Propionibacterium, which is known for its role in human skin microbiota. This organism has been associated with various clinical implications, particularly in the context of skin health and infections. It is recognized for its potential involvement in acne vulgaris, where it contributes to the inflammatory response in the skin. The presence of P. australiense can lead to the exacerbation of acne lesions through the production of pro-inflammatory mediators, thus playing a role in the pathogenesis of this common skin condition. In addition to its role in acne, P. australiense has been studied for its potential antimicrobial resistance mechanisms. Some strains exhibit resistance to commonly used antibiotics, which complicates treatment options for infections associated with this organism. Understanding the resistance patterns is crucial for effective management of acne and other skin infections. Moreover, P. australiense has been explored for its potential as a probiotic. Some studies suggest that certain strains may have beneficial effects on skin health, possibly aiding in the modulation of the skin microbiome and enhancing the skin's barrier function. This highlights the dual role of P. australiense as both a potential pathogen and a beneficial organism, depending on the context of its presence. Overall, the clinical relevance of Propionibacterium australiense lies in its association with skin disorders, its potential for antimicrobial resistance, and its emerging role in probiotic applications for skin health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Propionibacterium australiense is a species of bacteria that is primarily associated with the human skin microbiome and is known for its role in the fermentation of certain organic compounds. This microorganism thrives in the sebaceous glands of the skin, where it plays a crucial role in maintaining skin health and balance. Its presence is particularly notable in areas with high concentrations of oil, such as the face and scalp, where it contributes to the breakdown of sebum, a natural oil produced by the skin. In terms of ecological niches, P. australiense is often found in environments that are rich in lipids and organic matter, making it well-adapted to the microenvironments created by human skin. The bacterium is involved in the production of short-chain fatty acids, which can help lower the pH of the skin surface, thus providing a protective barrier against pathogenic organisms. Additionally, P. australiense exhibits symbiotic relationships with other skin microbiota, contributing to a balanced microbial community that can prevent the overgrowth of harmful bacteria. This interaction is vital for the overall health of the skin, as it helps to maintain the homeostasis of the skin microbiome. Overall, Propionibacterium australiense is an important player in the human skin biome, showcasing how microorganisms can adapt to specific habitats and contribute positively to their environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Propionibacterium australiense has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where it is utilized in the fermentation process to produce propionic acid, a valuable organic compound used as a preservative and in the production of various chemicals. This fermentation process not only contributes to food preservation but also enhances the flavor profile of certain dairy products, particularly in cheese production. In the realm of waste management, Propionibacterium australiense has been studied for its ability to degrade organic waste materials. Its enzymatic activity allows it to break down complex organic compounds, making it a candidate for biodegradation processes that can help in the treatment of agricultural and food waste, thereby reducing environmental impact. Furthermore, the organism has potential applications in biofuel production. Through its metabolic pathways, Propionibacterium australiense can be involved in the conversion of biomass into biofuels, particularly through fermentation processes that yield bioethanol. This aligns with the growing demand for sustainable energy sources and the reduction of fossil fuel dependency. In pharmaceutical development, the unique metabolic properties of Propionibacterium australiense may lead to the discovery of novel compounds with antimicrobial properties. Research into its secondary metabolites could pave the way for new drug formulations, particularly in the fight against antibiotic-resistant bacteria. Overall, Propionibacterium australiense demonstrates a versatile profile that can be harnessed across multiple industries, making it a valuable microorganism in the pursuit of sustainable and innovative solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro	google/gemma-7b-it	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	microsoft/wizardlm-2-8x22b	anthropic/claude-3.5-sonnet	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openai/gpt-4	openai/gpt-4	openchat/openchat-7b	openchat/openchat-7b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5
Motility	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	anaerobic	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerotolerant ✗	aerotolerant ✗	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	false	true	true	true	true	false	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	N/A	true	false	true	false	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	coccus	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✓	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✓	coccus ✓	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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