Staphylococcus muscae

General Information

Staphylococcus muscae is a species of bacteria that belongs to the genus Staphylococcus. This microorganism is particularly interesting due to its association with flies, specifically the housefly (Musca domestica), from which it was first isolated. One of the unique aspects of S. muscae is its ecological niche, as it is commonly found in environments where flies are prevalent, such as decomposing organic matter and waste. This association with flies suggests that S. muscae may play a role in the microbial communities of these insects, potentially influencing their health and behavior. From a research perspective, S. muscae is valuable for studying the interactions between bacteria and insects. Understanding these interactions can provide insights into the transmission of pathogens and the role of flies as vectors in spreading bacterial infections. Additionally, the study of S. muscae can contribute to the broader understanding of the genus Staphylococcus, which includes several medically significant species. Moreover, S. muscae has been noted for its potential in biotechnological applications. For instance, its ability to survive in diverse and often harsh environments makes it a candidate for studying bacterial resilience and adaptation. This can have implications for developing new antimicrobial strategies and understanding bacterial survival mechanisms. In summary, Staphylococcus muscae is a fascinating bacterium due to its unique ecological niche, its potential role in the health and behavior of flies, and its broader implications for research in microbial ecology, pathogen transmission, and biotechnology.

Staphylococcus muscae is a fascinating species of bacteria that has garnered attention due to its unique ecological niche and potential implications in both environmental and health-related research. This organism is primarily associated with flies, particularly houseflies, which serve as vectors for its transmission. This association with insects highlights its role in the microbial ecology of animal waste and decaying organic matter, where it can thrive and contribute to the decomposition process. One of the most interesting aspects of S. muscae is its ability to produce a variety of bioactive compounds, which may have implications for both antimicrobial research and the development of new therapeutic agents. The potential for these compounds to inhibit the growth of pathogenic bacteria makes S. muscae a valuable candidate for further study in the field of natural product chemistry. Additionally, the organism's resilience in diverse environments, particularly in the presence of competing microbial flora, makes it a subject of interest for studies on microbial competition and adaptation. Understanding how S. muscae interacts with other microorganisms can provide insights into microbial community dynamics and the evolution of resistance mechanisms. Overall, Staphylococcus muscae stands out not only for its ecological significance but also for its potential applications in biotechnology and medicine, making it a noteworthy organism for ongoing research.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacillota

Class: Bacilli

Order: Bacillales

Family: Staphylococcaceae

Genus: Staphylococcus

Species: Staphylococcus muscae

NCBI ID

1294

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/900/187/005/GCA_900187005.1_50569_B01

File for sequence-based predictions:
GCA_900187005.1_50569_B01_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Staphylococcus muscae is a coagulase-negative staphylococcus that has been primarily associated with infections in animals, particularly in livestock and poultry. Its relevance in human health is less well-documented, but it has been isolated from human clinical specimens, suggesting a potential role in infections in immunocompromised individuals. The pathogenicity of S. muscae is not fully understood, but it may contribute to opportunistic infections due to its ability to form biofilms and resist phagocytosis. Antimicrobial resistance is a significant concern, as some strains exhibit resistance to common antibiotics, which complicates treatment options. While there is limited information on its specific immune evasion strategies, coagulase-negative staphylococci are known to possess mechanisms that allow them to evade the immune response, such as the production of polysaccharide capsules and biofilm formation. Overall, while S. muscae is primarily recognized in veterinary contexts, its potential implications in human health warrant further investigation, particularly in the context of nosocomial infections and the increasing prevalence of antibiotic-resistant strains.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Staphylococcus muscae is a bacterium commonly associated with the microbial communities found in the gastrointestinal tracts of various animals, particularly in flies and other insects. This organism thrives in environments where organic matter is abundant, such as decaying organic material and manure piles, which provide a rich source of nutrients. In these habitats, Staphylococcus muscae plays a crucial role in the decomposition process, contributing to nutrient cycling and the breakdown of complex organic compounds. Its presence in the gut microbiota of insects suggests a potential symbiotic relationship, where the bacterium aids in digestion and nutrient absorption for its host, while benefiting from the nutrient-rich environment of the gut. Additionally, Staphylococcus muscae can be found in urban environments where it may colonize surfaces contaminated with organic waste, further emphasizing its adaptability to various ecological niches. The organism's ability to thrive in such diverse habitats highlights its ecological significance and adaptability to changing environmental conditions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Staphylococcus muscae has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This bacterium is known for its ability to thrive in diverse environments, which can be harnessed for specific processes. In biotechnology, Staphylococcus muscae can be utilized in fermentation processes, where it may contribute to the production of valuable metabolites. Its metabolic pathways can be explored for the synthesis of bioactive compounds, which are essential in the development of pharmaceuticals. In the realm of waste management, Staphylococcus muscae has demonstrated capabilities in biodegradation, particularly in the breakdown of organic waste materials. This property can be leveraged in composting and other waste treatment systems to enhance the efficiency of waste decomposition and nutrient recycling. Furthermore, the enzymatic activities of Staphylococcus muscae can be investigated for their potential in biofuel production. By optimizing conditions for enzyme production, this microorganism could play a role in the conversion of biomass into biofuels, contributing to sustainable energy solutions. Overall, the versatility of Staphylococcus muscae in these applications highlights its significance in advancing industrial processes and promoting environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	anthropic/claude-3-haiku:beta	mistralai/mistral-7b-instruct	google/gemma-7b-it	openchat/openchat-7b	google/gemini-flash-1.5	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	beta	N/A	beta ✓	beta ✓	N/A	beta ✓	beta ✓	N/A	N/A	N/A	beta ✓	beta ✓	N/A	N/A	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	beta ✓	N/A	N/A	beta ✓	beta ✓	N/A	N/A	N/A	N/A
Cell shape	N/A	coccus	coccus	coccus	coccus	coccus	coccus	coccus	bacillus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus	coccus

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