Streptomyces hokutonensis

General Information

Streptomyces hokutonensis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites, including antibiotics, antifungals, and antitumor agents. One of the most intriguing aspects of S. hokutonensis is its potential for novel bioactive compound discovery. This species, like many in its genus, thrives in soil environments where it plays a crucial role in decomposing organic matter and contributing to soil health. Streptomyces species are well-known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their resilience and adaptability in various environments. The ability of S. hokutonensis to produce unique secondary metabolites makes it a valuable subject for biotechnological and pharmaceutical research. These compounds often have unique structures and mechanisms of action, which can lead to the development of new drugs and therapies. Additionally, the genetic and enzymatic pathways involved in the biosynthesis of these compounds are of significant interest. Understanding these pathways can lead to the engineering of S. hokutonensis or related species to enhance the production of desired compounds or to create entirely new ones. This makes S. hokutonensis not only a subject of ecological and environmental interest but also a potential powerhouse in the field of natural product chemistry and drug discovery. In summary, Streptomyces hokutonensis stands out due to its potential for producing novel bioactive compounds, its complex life cycle, and its significant role in soil ecosystems. These characteristics make it a valuable organism for scientific research and biotechnological applications.

Streptomyces hokutonensis is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species was first isolated from soil samples in Japan and has since garnered attention due to its potential in natural product discovery. One of the most notable characteristics of S. hokutonensis is its ability to synthesize unique secondary metabolites, including antibiotics and antifungal agents. These compounds are of significant interest in the fight against antibiotic-resistant pathogens, highlighting the organism's potential as a source of new therapeutic agents. Additionally, S. hokutonensis exhibits a complex life cycle typical of the genus Streptomyces, which includes the formation of aerial hyphae and spores. This life cycle not only contributes to its ecological success in diverse environments but also facilitates the production of secondary metabolites during specific growth phases. The genetic and metabolic pathways involved in the biosynthesis of these compounds are actively being studied, providing insights into microbial secondary metabolism and the potential for biotechnological applications. Furthermore, the genome of S. hokutonensis has been sequenced, revealing a rich repertoire of biosynthetic gene clusters. This genomic information is invaluable for researchers aiming to harness the organism's capabilities for drug discovery and development. The ability to manipulate its genetic makeup opens up possibilities for engineering strains that can produce novel compounds or enhance the yield of existing ones. Overall, Streptomyces hokutonensis stands out as a promising candidate for further exploration in the fields of microbiology, pharmacology, and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces hokutonensis

NCBI ID

1306990

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/376/565/GCA_000376565.1_ASM37656v1

File for sequence-based predictions:
GCA_000376565.1_ASM37656v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces hokutonensis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This particular species has been studied for its potential in producing novel antimicrobial agents, making it relevant in the context of antimicrobial resistance that is increasingly challenging modern medicine. Research has indicated that extracts from Streptomyces hokutonensis exhibit activity against various pathogenic bacteria, which could be harnessed for therapeutic purposes. In terms of human health, Streptomyces hokutonensis may also play a role in the microbiome, contributing to the balance of microbial communities in the environment and potentially influencing human health indirectly. However, its direct pathogenicity in humans is not well-documented, suggesting that it is primarily beneficial rather than harmful. Moreover, the organism's ability to produce secondary metabolites could have implications for the development of probiotics or other therapeutic agents. The exploration of its metabolites may lead to the discovery of new drugs that can combat infections caused by resistant strains of bacteria. Overall, while Streptomyces hokutonensis is not widely recognized for causing infections in humans, its contributions to antimicrobial production and potential applications in medicine underscore its importance in the ongoing search for new therapeutic options in the face of rising antimicrobial resistance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces hokutonensis is a species of actinobacteria that is primarily found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes significantly to nutrient cycling within these biomes. Soil Microhabitats: Within the soil, Streptomyces hokutonensis occupies various microhabitats, often found in association with plant roots. This relationship can lead to enhanced nutrient availability for plants, as the bacterium helps in the mineralization of nutrients. The presence of this microorganism can improve soil health and fertility, making it an important player in terrestrial ecosystems. Symbiotic Interactions: Streptomyces hokutonensis is known for its potential symbiotic relationships with plants, where it may promote plant growth through the production of phytohormones. This interaction not only benefits the plants but also allows the bacterium to thrive in nutrient-rich environments created by plant exudates. Adaptation to Environmental Conditions: This species exhibits remarkable adaptability to varying soil conditions, including changes in moisture and pH levels. Its resilience allows it to persist in diverse habitats, from arid soils to moist forest floors. The ability to produce a wide range of secondary metabolites also enables Streptomyces hokutonensis to compete effectively with other microorganisms, further solidifying its role in the ecosystem. In summary, Streptomyces hokutonensis is a vital component of soil biomes, contributing to nutrient cycling, plant health, and overall ecosystem stability through its various ecological interactions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces hokutonensis is recognized for its significant contributions to various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This actinobacterium is known for its ability to produce a wide range of bioactive compounds, including antibiotics and other secondary metabolites, which are crucial in the development of new medications. For instance, it has been documented to produce compounds that exhibit antimicrobial properties, making it a valuable resource in the search for new antibiotics to combat resistant strains of bacteria. In the realm of biotechnology, Streptomyces hokutonensis is involved in fermentation processes that can lead to the production of enzymes and other metabolites. These enzymes can be utilized in various applications, such as in the food industry for the fermentation of dairy products or in the production of bioactive peptides. Moreover, this microorganism has potential applications in waste management through its ability to degrade complex organic materials. Its enzymatic activity can facilitate the biodegradation of pollutants, making it a candidate for bioremediation efforts aimed at cleaning up contaminated environments. In the context of biofuel production, Streptomyces hokutonensis may play a role in the breakdown of lignocellulosic biomass, which is essential for the conversion of plant materials into fermentable sugars. These sugars can then be utilized in the production of bioethanol, contributing to sustainable energy solutions. Overall, Streptomyces hokutonensis demonstrates a multifaceted potential in various industries, particularly through its involvement in fermentation, biodegradation, and the production of valuable bioactive compounds, making it a significant organism in the field of industrial microbiology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro	mistralai/mistral-7b-instruct	google/palm-2-chat-bison-32k	anthropic/claude-3.5-sonnet	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	false	true	false	true	true	true	true	true	true	false	false	false	false	false	false	true	true	true	true	true	true	true	true	true	true
Host association	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

Back to Search