Paraburkholderia fungorum

General Information

Paraburkholderia fungorum is a fascinating microorganism that has garnered significant interest in various fields of research due to its unique and valuable characteristics. This bacterium is part of the Paraburkholderia genus, which is known for its environmental versatility and biotechnological potential. One of the most intriguing aspects of Paraburkholderia fungorum is its ability to degrade a wide range of environmental pollutants. This makes it a prime candidate for bioremediation efforts, where it can be employed to clean up contaminated soils and water bodies. Its metabolic versatility allows it to break down complex organic compounds, including aromatic hydrocarbons, which are often challenging to degrade. Additionally, Paraburkholderia fungorum has been studied for its plant growth-promoting properties. It can form beneficial associations with plants, enhancing their growth by facilitating nutrient uptake and providing protection against certain pathogens. This symbiotic relationship is particularly valuable in sustainable agriculture, where the use of chemical fertilizers and pesticides can be minimized. From a biotechnological perspective, Paraburkholderia fungorum is notable for its production of bioactive compounds. These compounds have potential applications in medicine and industry, including the development of new antibiotics and enzymes for industrial processes. The bacterium's ability to produce these compounds under various environmental conditions makes it a versatile tool for biotechnological innovation. Moreover, the genetic and metabolic pathways of Paraburkholderia fungorum are of great interest to researchers. The organism's genome has been sequenced, providing insights into its metabolic capabilities and regulatory mechanisms. This genetic information is crucial for engineering strains with enhanced capabilities for specific applications, such as improved pollutant degradation or increased production of valuable metabolites. In summary, Paraburkholderia fungorum stands out due to its environmental adaptability, bioremediation potential, plant growth-promoting abilities, and production of bioactive compounds. These characteristics make it a valuable subject of study in environmental science, agriculture, and biotechnology, offering promising solutions to some of the pressing challenges in these fields.

Paraburkholderia fungorum is a fascinating bacterium that has garnered attention due to its unique ecological roles and potential applications in biotechnology. This organism is primarily known for its ability to degrade a variety of organic compounds, making it a valuable player in bioremediation efforts. Its metabolic versatility allows it to thrive in diverse environments, including soil and plant rhizospheres, where it can interact with various plant species. One of the most interesting aspects of Paraburkholderia fungorum is its capacity to form symbiotic relationships with plants. It has been shown to promote plant growth by enhancing nutrient availability and improving stress tolerance, which is particularly valuable in agricultural settings. This characteristic positions P. fungorum as a potential biofertilizer, contributing to sustainable farming practices. Additionally, Paraburkholderia fungorum has been studied for its role in the nitrogen cycle. Its ability to fix atmospheric nitrogen can significantly benefit soil fertility, making it an important organism in both natural ecosystems and agricultural systems. Furthermore, the genomic and metabolic pathways of P. fungorum are of great interest to researchers. The organism's genetic makeup provides insights into the evolution of symbiotic relationships and metabolic adaptations, which can inform future studies in microbial ecology and evolutionary biology. Overall, Paraburkholderia fungorum stands out as a remarkable microorganism with significant implications for environmental science and agriculture.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Burkholderiales

Family: Burkholderiaceae

Genus: Paraburkholderia

Species: Paraburkholderia fungorum

NCBI ID

134537

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/961/515/GCA_000961515.1_ASM96151v1

File for sequence-based predictions:
GCA_000961515.1_ASM96151v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Paraburkholderia fungorum is a member of the Burkholderia genus, which has garnered attention due to its clinical implications in human health. This microorganism is known for its role in infections and has been associated with various disease states, particularly in immunocompromised individuals. It can act as an opportunistic pathogen, leading to respiratory infections, skin infections, and systemic infections in susceptible populations. One of the notable features of Paraburkholderia fungorum is its potential for antimicrobial resistance. Strains of this organism have shown resistance to multiple classes of antibiotics, complicating treatment options and necessitating careful consideration in clinical settings. This resistance is often attributed to the presence of specific resistance genes and efflux pumps that allow the organism to evade the effects of antimicrobial agents. In terms of its interaction with the human body, Paraburkholderia fungorum can evade the immune response through various mechanisms, including the production of biofilms and the secretion of virulence factors that inhibit phagocytosis. This ability to persist in the host environment contributes to its pathogenicity and the difficulty in eradicating infections once established. While Paraburkholderia fungorum is primarily recognized for its pathogenic potential, it also has applications in biotechnology and environmental microbiology, particularly in bioremediation processes. However, its clinical relevance cannot be understated, especially in the context of emerging infections and the challenges posed by antimicrobial resistance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Paraburkholderia fungorum is a versatile microorganism commonly found in a variety of soil ecosystems and plant-associated environments. This bacterium is particularly notable for its ability to thrive in nutrient-rich soils, where it plays a crucial role in the decomposition of organic matter and nutrient cycling. Its presence is often linked to the rhizosphere, the region of soil directly influenced by root secretions and associated soil microorganisms, where it can establish beneficial relationships with plants. In the rhizosphere, Paraburkholderia fungorum engages in symbiotic interactions with various plant species, enhancing nutrient uptake, particularly nitrogen, through its ability to fix atmospheric nitrogen. This relationship not only benefits the plants but also contributes to soil fertility, making it an essential player in agricultural ecosystems. Additionally, this microorganism has been isolated from tropical rainforests and wetlands, where it contributes to the breakdown of complex organic materials, thus supporting the overall health of these biodiverse environments. Its adaptability to different moisture levels and nutrient availability allows it to occupy various ecological niches, from aerobic to anaerobic conditions, showcasing its ecological versatility. Overall, Paraburkholderia fungorum is a key component of its associated biomes, influencing both the microbial community structure and the health of the ecosystems it inhabits.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Paraburkholderia fungorum has shown significant potential in various industrial applications across multiple sectors. One of the most notable areas is biotechnology, where P. fungorum is utilized in fermentation processes to produce valuable metabolites, including organic acids and enzymes. These metabolites can be harnessed for food preservation, flavor enhancement, and as biocatalysts in chemical reactions. In the realm of waste management, P. fungorum has demonstrated capabilities in biodegradation of environmental pollutants, particularly in the degradation of aromatic compounds and heavy metals. This makes it a candidate for bioremediation strategies aimed at cleaning contaminated sites, thus contributing to environmental sustainability. Furthermore, P. fungorum is being explored for its role in biofuel production. Its metabolic pathways can be engineered to enhance the production of bioethanol and other biofuels through fermentation of lignocellulosic biomass, which is a renewable resource. This application is particularly relevant in the context of reducing reliance on fossil fuels and promoting cleaner energy sources. In the pharmaceutical development sector, P. fungorum has been investigated for its potential to produce novel bioactive compounds that could lead to the development of new drugs. Its ability to synthesize complex molecules through enzyme production is of particular interest in the pharmaceutical industry, where such compounds can serve as precursors for drug synthesis. Overall, Paraburkholderia fungorum represents a versatile microorganism with promising applications in biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its importance in advancing industrial processes and environmental solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	mistralai/mixtral-8x7b-instruct:nitro	anthropic/claude-3.5-sonnet	mistralai/mistral-7b-instruct	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	google/gemma-7b-it	google/gemma-7b-it	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	TRUE	false ✗	true ✓	false ✗	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	facultatively anaerobic ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	false	false
Host association	N/A	true	false	true	false	false	true	false	false	false	false	false	true	true	false	false	false	false	false	false	true	true	false	false	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	beta ✗	beta ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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