Chromobacterium amazonense

General Information

Chromobacterium amazonense is a fascinating microorganism that has garnered attention due to its unique ecological niche and potential biotechnological applications. This bacterium was first isolated from the Amazon rainforest, a region known for its rich biodiversity and unique microbial communities. One of the most intriguing aspects of C. amazonense is its ability to produce a variety of bioactive compounds, including antibiotics and pigments, which have significant implications for medical and industrial applications. One of the key characteristics of Chromobacterium amazonense is its production of violacein, a purple pigment with notable antimicrobial, antiviral, and anticancer properties. This pigment has been the subject of extensive research due to its potential therapeutic applications. Additionally, C. amazonense has been found to produce other secondary metabolites that exhibit a range of biological activities, making it a valuable organism for natural product discovery. Another interesting feature of C. amazonense is its adaptability to different environmental conditions. This bacterium can thrive in diverse habitats, from soil and water to plant surfaces, indicating a high level of ecological versatility. This adaptability is of particular interest to researchers studying microbial ecology and the interactions between microorganisms and their environments. In summary, Chromobacterium amazonense stands out due to its production of bioactive compounds, ecological versatility, and potential for biotechnological applications. Its unique properties make it a valuable subject for ongoing research in various scientific fields, including microbiology, pharmacology, and environmental science.

Chromobacterium amazonense is a fascinating bacterium primarily isolated from the Amazon rainforest, showcasing a remarkable adaptability to its unique environment. This organism is notable for its ability to produce a variety of bioactive compounds, including antimicrobial agents, which have garnered significant interest in pharmaceutical research. The production of these compounds positions C. amazonense as a potential source for novel antibiotics, especially in an era where antibiotic resistance is a growing concern. One of the most intriguing aspects of C. amazonense is its metabolic versatility, allowing it to thrive in diverse ecological niches. This versatility is not only important for its survival in the competitive microbial community of the Amazon but also makes it a valuable model for studying metabolic pathways and biotechnological applications. Additionally, C. amazonense has been studied for its bioremediation potential, particularly in the degradation of environmental pollutants. Its ability to metabolize various organic compounds suggests that it could play a role in cleaning up contaminated environments, making it a subject of interest for environmental microbiology. Overall, the unique characteristics of Chromobacterium amazonense—from its bioactive compound production to its metabolic capabilities—underscore its importance in both ecological and applied microbiological research.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Neisseriales

Family: Chromobacteriaceae

Genus: Chromobacterium

Species: Chromobacterium amazonense

NCBI ID

1382803

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/016/858/235/GCA_016858235.1_ASM1685823v1

File for sequence-based predictions:
GCA_016858235.1_ASM1685823v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Chromobacterium amazonense is a Gram-negative organism primarily found in tropical and subtropical environments, particularly in soil and water. It has been associated with various clinical implications, particularly in immunocompromised patients. Infections caused by C. amazonense can lead to serious conditions such as sepsis, wound infections, and pneumonia. The organism is known for its pathogenicity, which is attributed to its ability to produce virulence factors, including proteases and hemolysins, that facilitate tissue invasion and damage. One of the notable aspects of C. amazonense is its potential for antimicrobial resistance. Isolates have shown resistance to multiple classes of antibiotics, which complicates treatment options for infections. This resistance is often linked to the presence of plasmids that carry resistance genes, making it a concern in clinical settings. In terms of immune evasion, C. amazonense can alter its surface structures to avoid detection by the host's immune system, contributing to its virulence. The organism has been implicated in outbreaks, particularly in regions where it is endemic, highlighting its relevance in public health. While C. amazonense is primarily recognized for its pathogenic potential, there is ongoing research into its possible medical applications, such as the use of its metabolites in biotechnological processes. However, its clinical significance remains largely focused on its role as a pathogen in human infections.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Chromobacterium amazonense is a bacterium commonly found in the tropical rainforests of the Amazon Basin. This microorganism thrives in freshwater environments, particularly in areas with rich organic matter and high humidity. Its ecological niche is often associated with the soil and water of these biomes, where it plays a significant role in nutrient cycling and organic matter decomposition. In these tropical ecosystems, C. amazonense is known for its ability to degrade various organic compounds, contributing to the overall health of the environment. It interacts with other microorganisms, forming complex microbial communities that enhance soil fertility and promote plant growth. This bacterium is also involved in symbiotic relationships with certain plants, aiding in nutrient uptake and enhancing plant resilience against pathogens. Furthermore, C. amazonense exhibits remarkable environmental adaptations, allowing it to survive in varying conditions of moisture and temperature typical of the Amazon rainforest. Its presence is indicative of a healthy ecosystem, as it helps maintain the balance of microbial populations and supports the intricate web of life found in these biodiverse habitats.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Chromobacterium amazonense has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where C. amazonense is recognized for its ability to produce a range of valuable metabolites, including antimicrobial compounds. This property is particularly useful in the development of new pharmaceuticals, as these compounds can serve as lead structures for drug discovery and development. In the realm of waste management, C. amazonense has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic pollutants. This makes it a candidate for use in bioremediation processes, where it can help in the detoxification of contaminated environments, such as oil spills or heavy metal-laden sites. Furthermore, C. amazonense has been explored for its role in biofuel production. The organism can participate in fermentation processes that convert biomass into bioethanol, providing a sustainable alternative to fossil fuels. Its metabolic pathways can be harnessed to optimize the yield of biofuels from various organic substrates. Additionally, the enzymatic activities of C. amazonense are of interest in industrial enzyme production. The enzymes produced by this microorganism can be utilized in various applications, including food processing, textile manufacturing, and even in the production of biodegradable plastics. The versatility of C. amazonense in these processes highlights its importance in advancing sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openchat/openchat-7b	anthropic/claude-3.5-sonnet	google/gemini-pro	google/gemini-pro	google/gemma-7b-it	google/gemma-7b-it	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	N/A	true	false	true	true	true	false	true	false	false	true	true	false	false	false	false	true	true	false	false	true	true	true	true	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	false	false	true	true
Host association	N/A	true	true	true	true	true	true	true	false	false	true	true	false	false	false	false	true	true	true	true	true	true	true	true	false	false	false	false	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	beta	N/A	beta	beta	beta	N/A	N/A	N/A	N/A	beta	beta	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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