Micromonospora orduensis

General Information

Micromonospora orduensis is a fascinating microorganism belonging to the genus Micromonospora, which is well-known for its prolific production of bioactive compounds. This species was first isolated from soil samples, highlighting its natural habitat in terrestrial environments. One of the most intriguing aspects of M. orduensis is its ability to produce a variety of secondary metabolites, many of which have significant pharmaceutical potential. These metabolites include antibiotics, antifungals, and antitumor agents, making M. orduensis a valuable subject for drug discovery and development. What makes Micromonospora orduensis particularly interesting is its genetic and metabolic diversity. The genome of M. orduensis encodes numerous biosynthetic gene clusters that are responsible for the synthesis of these bioactive compounds. This genetic richness provides a treasure trove for researchers looking to discover new drugs or understand the mechanisms of antibiotic resistance. Additionally, M. orduensis exhibits a unique morphological characteristic: it forms branching filaments that fragment into rod-shaped or coccoid elements. This distinctive morphology is not only a key identification feature but also plays a role in its ecological adaptability and interaction with other microorganisms in the soil. From a biotechnological perspective, M. orduensis is valuable for its potential in bioremediation. Its ability to degrade complex organic compounds makes it a candidate for cleaning up contaminated environments. Furthermore, the enzymes produced by M. orduensis are of interest for industrial applications, including the breakdown of plant biomass for biofuel production. In summary, Micromonospora orduensis is a microorganism of significant interest due to its production of bioactive compounds, genetic diversity, and biotechnological applications. Its study not only advances our understanding of microbial ecology and evolution but also holds promise for the development of new therapeutic agents and environmental solutions.

Micromonospora orduensis is a fascinating actinobacterium that has garnered attention due to its unique ecological niche and potential biotechnological applications. This microorganism is primarily isolated from soil environments, particularly in regions with rich organic matter, which highlights its role in nutrient cycling and soil health. What makes M. orduensis particularly interesting is its ability to produce a variety of bioactive compounds, including antibiotics and enzymes, which can be valuable in pharmaceutical and agricultural industries. The genus Micromonospora is known for its diverse metabolic capabilities, and M. orduensis contributes to this diversity with its potential to degrade complex organic materials. This characteristic not only aids in bioremediation efforts but also positions M. orduensis as a candidate for further research into sustainable agricultural practices. Moreover, the genomic analysis of M. orduensis has revealed the presence of gene clusters responsible for secondary metabolite production, making it a subject of interest for researchers looking to discover new natural products. The exploration of these metabolites could lead to the development of novel antibiotics, especially in the face of rising antibiotic resistance. In summary, Micromonospora orduensis stands out due to its ecological significance, potential for biotechnological applications, and the promise it holds for future discoveries in natural product chemistry.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micromonosporales

Family: Micromonosporaceae

Genus: Micromonospora

Species: Micromonospora orduensis

NCBI ID

1420891

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/006/228/125/GCF_006228125.1_ASM622812v1

File for sequence-based predictions:
GCF_006228125.1_ASM622812v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Micromonospora orduensis is a member of the genus Micromonospora, which is known for its role in the production of various bioactive compounds, including antibiotics. This species has been isolated from soil and is of interest due to its potential antimicrobial properties. It has been studied for its ability to produce antibiotics that may be effective against a range of pathogenic bacteria, making it a candidate for further research in the development of new therapeutic agents. In terms of pathogenicity, there is limited documentation regarding Micromonospora orduensis as a direct cause of human disease. However, its close relatives within the Micromonospora genus have been implicated in opportunistic infections, particularly in immunocompromised patients. This raises concerns about the potential for infections in vulnerable populations, although specific cases involving M. orduensis have not been extensively reported. The organism's role in antimicrobial resistance is also an area of interest, as the production of antibiotics by Micromonospora orduensis could contribute to the understanding of resistance mechanisms in other bacteria. The study of its metabolic pathways may provide insights into how it can evade immune responses or how it can be harnessed to combat resistant strains of bacteria. Overall, while Micromonospora orduensis is not widely recognized for direct clinical implications, its potential in therapeutics and the broader context of its genus in antibiotic production make it a significant subject for future research in microbiology and pharmacology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Micromonospora orduensis is a species of actinobacteria that is primarily associated with soil ecosystems and marine environments. This microorganism thrives in nutrient-rich substrates, often found in decaying organic matter, where it plays a crucial role in the decomposition process. Its presence is particularly notable in terrestrial biomes such as temperate forests and tropical rainforests, where it contributes to nutrient cycling and soil health by breaking down complex organic compounds into simpler forms that can be utilized by plants and other organisms. In marine habitats, Micromonospora orduensis has been isolated from sediments and biofilms on submerged surfaces, indicating its adaptability to saline conditions. Here, it participates in the degradation of organic materials, thus influencing the biogeochemical cycles of the marine ecosystem. The organism's ability to produce various bioactive compounds also suggests a role in antibiotic production, which can impact microbial community dynamics and offer competitive advantages in its ecological niche. Overall, Micromonospora orduensis exemplifies the intricate relationships within its biomes, showcasing its importance in both soil health and marine nutrient cycling, while also highlighting its potential for biotechnological applications in medicine and agriculture.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Micromonospora orduensis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics. This capability is particularly valuable in the development of new pharmaceuticals, as Micromonospora orduensis can be harnessed for fermentation processes to yield these therapeutic agents. In the realm of waste management, Micromonospora orduensis has demonstrated effectiveness in biodegradation processes, where it can break down complex organic materials, thus aiding in the treatment of wastewater and reducing environmental pollution. Its enzymatic activity allows it to degrade various pollutants, making it a candidate for bioremediation efforts. Furthermore, the organism has potential applications in biofuel production. By utilizing its metabolic pathways, Micromonospora orduensis can contribute to the conversion of biomass into biofuels through fermentation processes, enhancing the efficiency of biofuel production systems. Overall, Micromonospora orduensis stands out as a versatile microorganism with promising applications in pharmaceutical development, waste management, and biofuel production, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro	mistralai/mistral-7b-instruct	google/palm-2-chat-bison-32k	google/gemma-7b-it	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	false	true	true	true	true	false	true	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	false	true	true	true	true	false	true	true	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	true	true	false	false
Host association	FALSE	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus

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