Streptomyces graminilatus

General Information

Streptomyces graminilatus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites, including antibiotics, antifungals, and immunosuppressants. One of the most intriguing aspects of S. graminilatus is its potential for novel antibiotic production, making it a valuable subject for pharmaceutical research. This species was originally isolated from soil, a common habitat for Streptomyces species, which are known for their complex life cycles and ability to degrade a wide range of organic materials. Streptomyces graminilatus exhibits a filamentous form, which is characteristic of the genus and contributes to its ability to colonize and decompose organic matter in soil environments. The organism's genome is rich in biosynthetic gene clusters, which are responsible for the synthesis of its diverse array of secondary metabolites. The discovery of new compounds from S. graminilatus could lead to the development of new drugs to combat antibiotic-resistant bacteria, a growing concern in modern medicine. Additionally, S. graminilatus has been noted for its potential in agricultural applications. Its ability to produce natural antibiotics can help in controlling plant pathogens, promoting healthier crop growth. This dual role in both medicine and agriculture underscores the importance of continued research into this versatile microorganism. In summary, Streptomyces graminilatus is a microorganism of significant interest due to its potential for novel antibiotic production, its complex life cycle, and its applications in both pharmaceutical and agricultural fields. Its study not only advances our understanding of microbial ecology and secondary metabolism but also holds promise for practical applications that can address some of the pressing challenges in health and agriculture today.

Streptomyces graminilatus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, including antibiotics and antifungal agents. This species is particularly interesting due to its ecological role in soil environments, where it contributes to the degradation of organic matter and the cycling of nutrients. Its capacity to synthesize secondary metabolites makes it a valuable organism in pharmaceutical research, as many compounds derived from Streptomyces species have been used in the development of important drugs, such as streptomycin and tetracycline. One of the unique aspects of S. graminilatus is its association with grasses, which suggests a specialized ecological niche. This relationship may enhance its ability to produce specific metabolites that can protect its host plants from pathogens or promote plant growth. The potential for biocontrol applications in agriculture is significant, as harnessing the natural capabilities of S. graminilatus could lead to sustainable practices that reduce reliance on chemical pesticides. Furthermore, the genomic and metabolic pathways of S. graminilatus are of great interest to researchers aiming to understand the biosynthesis of its secondary metabolites. Studying this organism can provide insights into the genetic and enzymatic mechanisms that underlie the production of novel compounds, which could lead to the discovery of new therapeutic agents. Overall, Streptomyces graminilatus stands out as a promising candidate for further exploration in both environmental microbiology and drug discovery.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces graminilatus

NCBI ID

1464070

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/418/565/GCF_001418565.1_ASM141856v1

File for sequence-based predictions:
GCF_001418565.1_ASM141856v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces graminilatus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. graminilatus itself is not commonly associated with human infections, its relatives have been implicated in various infections and can exhibit pathogenicity under certain conditions. This organism is primarily found in soil and is known for its ability to degrade complex organic materials, which contributes to its ecological importance. In terms of human health, Streptomyces species are often studied for their potential as probiotics and their role in promoting gut health. However, the specific clinical applications of S. graminilatus are not well-documented, and its direct impact on human health remains largely unexplored. One of the notable aspects of Streptomyces species is their ability to produce a wide range of secondary metabolites, including antibiotics such as streptomycin and tetracycline. This characteristic makes them valuable in the field of antimicrobial resistance, as they can serve as a source for new antimicrobial agents to combat resistant strains of bacteria. Furthermore, the interaction of S. graminilatus with the human body is not well characterized, and there is limited information regarding its immune evasion strategies or any known outbreaks associated with this specific species. Overall, while Streptomyces graminilatus may not have direct clinical implications, its relatives and the broader genus play a crucial role in antibiotic production and have potential applications in medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces graminilatus is a species of actinobacteria commonly found in soil ecosystems, particularly in agricultural settings. This microorganism thrives in nutrient-rich soils where it plays a crucial role in the decomposition of organic matter. Its ability to produce a variety of bioactive compounds makes it significant in the soil microbiome, contributing to nutrient cycling and soil health. Ecological Niches: - _Streptomyces graminilatus occupies a niche where it interacts with plant roots, often forming beneficial relationships that enhance plant growth. This symbiotic relationship can lead to improved nutrient uptake for plants, particularly in nitrogen-poor soils. Habitats: - This organism is predominantly found in agricultural fields, grasslands, and forested areas, where it can decompose plant material and contribute to soil fertility. Its presence is often associated with healthy soil ecosystems that support diverse plant life. Environmental Adaptation: - Streptomyces graminilatus exhibits remarkable adaptability to varying soil conditions, including changes in pH and moisture levels. This adaptability allows it to thrive in different environments, making it a resilient component of the soil microbiome. Notable Interactions: - The bacterium is known for its role in antibiotic production, which can inhibit the growth of pathogenic microorganisms in the soil, thus promoting a balanced ecosystem. This characteristic not only aids in plant health but also contributes to the overall biodiversity of the soil community.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces graminilatus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is crucial for the production of these valuable metabolites. In the realm of waste management, Streptomyces graminilatus has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of agricultural and industrial waste. Its enzymatic activity allows it to degrade pollutants, making it a candidate for bioremediation processes. Furthermore, in biofuel production, this microorganism can contribute to the conversion of biomass into biofuels through fermentation processes, enhancing the efficiency of biofuel generation. In pharmaceutical development, the secondary metabolites produced by Streptomyces graminilatus are of great interest, as they can lead to the discovery of new drugs and therapeutic agents. The organism's ability to synthesize unique compounds makes it a valuable resource in the search for novel pharmaceuticals. Overall, Streptomyces graminilatus exemplifies the diverse industrial applications of microorganisms, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its importance in sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-pro	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	false	false	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true
Host association	FALSE	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

Back to Search