Amycolatopsis oliviviridis

General Information

Amycolatopsis oliviviridis is a fascinating microorganism belonging to the genus Amycolatopsis, which is renowned for its ability to produce a wide array of bioactive compounds. One of the most notable features of A. oliviviridis is its capacity to synthesize antibiotics and other secondary metabolites that have significant pharmaceutical applications. This makes it a valuable subject of study in the field of natural product chemistry and drug discovery. Amycolatopsis oliviviridis is also interesting due to its ecological role and adaptability. It is typically found in soil environments, where it contributes to the decomposition of organic matter and the cycling of nutrients. The organism's ability to thrive in diverse and often harsh environmental conditions highlights its robust metabolic pathways and genetic versatility. From a biotechnological perspective, A. oliviviridis is particularly valuable because of its potential in bioremediation. The species has been studied for its ability to degrade various pollutants, including complex organic compounds, which underscores its utility in environmental cleanup efforts. In summary, Amycolatopsis oliviviridis stands out due to its antibiotic production, ecological significance, and biotechnological applications. These characteristics make it a key organism for ongoing research in multiple scientific disciplines.

Amycolatopsis oliviviridis is a fascinating actinobacterium that has garnered attention due to its unique metabolic capabilities and potential applications in biotechnology. This microorganism is particularly notable for its ability to produce a variety of bioactive compounds, including antibiotics and other secondary metabolites, which are of great interest in pharmaceutical research. The discovery of novel compounds from A. oliviviridis could lead to the development of new therapeutic agents, especially in the face of rising antibiotic resistance. One of the most intriguing aspects of A. oliviviridis is its ecological role in soil environments, where it contributes to the degradation of complex organic materials. This ability not only highlights its importance in nutrient cycling but also positions it as a potential candidate for bioremediation efforts. The organism's capacity to break down pollutants could be harnessed to clean up contaminated environments, making it valuable for environmental biotechnology. Furthermore, A. oliviviridis has been studied for its genetic and metabolic pathways, providing insights into the biosynthesis of its secondary metabolites. Understanding these pathways can facilitate the engineering of strains for enhanced production of desired compounds, which is a significant area of research in synthetic biology. In summary, Amycolatopsis oliviviridis stands out not only for its biochemical potential but also for its ecological significance, making it a promising subject for further research in both pharmaceutical and environmental sciences.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Pseudonocardiales

Family: Pseudonocardiaceae

Genus: Amycolatopsis

Species: Amycolatopsis oliviviridis

NCBI ID

1471590

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/654/365/GCA_014654365.1_ASM1465436v1

File for sequence-based predictions:
GCA_014654365.1_ASM1465436v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The actinobacterium Amycolatopsis oliviviridis has garnered attention due to its potential clinical implications, particularly in the field of antimicrobial resistance and its role in human health. This organism is known for producing a variety of bioactive compounds, including antibiotics, which can be significant in the development of new therapeutic agents. Its ability to synthesize these compounds makes it a candidate for further research in antibiotic development and therapeutics. In terms of pathogenicity, Amycolatopsis oliviviridis is generally considered non-pathogenic; however, its close relatives within the genus may exhibit pathogenic traits. This highlights the importance of understanding the genetic and biochemical pathways that contribute to its antibiotic production, as well as its potential interactions with human microbiota. Moreover, the organism's role in immune evasion strategies is an area of interest, particularly in how it may influence the human immune system through its metabolites. While there are no well-documented outbreaks or infections directly associated with Amycolatopsis oliviviridis, its presence in various environmental samples suggests a need for further investigation into its ecological and clinical relevance. Overall, the study of Amycolatopsis oliviviridis could provide insights into microbial interactions within the human body and contribute to the development of novel probiotics or vaccines aimed at enhancing human health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Amycolatopsis oliviviridis is a species of actinobacteria that is primarily found in soil environments and decaying organic matter. This microorganism thrives in nutrient-rich substrates, often associated with the decomposition of plant material. Its ecological niche is characterized by its ability to degrade complex organic compounds, contributing to nutrient cycling within the ecosystem. Soil Biomes: In soil biomes, A. oliviviridis plays a crucial role in soil health by breaking down organic matter, which enhances soil fertility and structure. This process not only aids in the release of nutrients but also supports the growth of other microorganisms and plants, establishing a dynamic microbial community. Symbiotic Relationships: Amycolatopsis oliviviridis has been noted for its potential symbiotic relationships with various plants. By promoting plant growth through the production of growth-promoting substances, it can enhance the overall productivity of the ecosystem. This interaction exemplifies the mutualistic relationships that can exist between soil bacteria and plant life. Adaptation to Environmental Conditions: This microorganism exhibits remarkable adaptability to varying environmental conditions, including changes in moisture and nutrient availability. Its ability to survive in drought-prone areas and nutrient-poor soils highlights its ecological resilience and importance in maintaining soil biodiversity. In summary, Amycolatopsis oliviviridis is integral to the health of terrestrial ecosystems, particularly in soil biomes, where it contributes to organic matter decomposition, nutrient cycling, and plant growth promotion, thereby sustaining the ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Amycolatopsis oliviviridis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Amycolatopsis oliviviridis has demonstrated capabilities in biodegradation, effectively breaking down complex organic materials and pollutants. This makes it a valuable asset in the treatment of industrial waste and the remediation of contaminated environments. Furthermore, the organism has potential applications in biofuel production, where its metabolic pathways can be harnessed to convert biomass into renewable energy sources. The enzymatic activity of Amycolatopsis oliviviridis can facilitate the breakdown of lignocellulosic materials, enhancing the efficiency of biofuel generation processes. Overall, Amycolatopsis oliviviridis stands out as a versatile microorganism with promising applications across pharmaceutical development, biotechnology, waste management, and biofuel production, making it a subject of interest for further research and industrial exploitation.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemma-7b-it	google/gemini-flash-1.5	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3.5-sonnet	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemini-pro	google/gemini-pro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	N/A	N/A	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	false	false	false	false	true	false	false	false	false	false	true	true	false	false	false	false	false	false	false	false	true	true	false	false	false	false	true	true
Host association	N/A	false	true	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Hemolysis	N/A	alpha	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus

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