Streptomyces lunaelactis

General Information

Streptomyces lunaelactis is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. This species was first isolated from a moonmilk deposit in a cave, which is a unique and rare environment, contributing to its intriguing nature. One of the most notable features of S. lunaelactis is its ability to produce a variety of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable subject for pharmaceutical research and biotechnological applications. The genome of S. lunaelactis reveals a wealth of biosynthetic gene clusters, indicating its potential to produce novel compounds that could be harnessed for medical and industrial purposes. Its unique habitat and the resulting adaptations also provide insights into microbial survival and metabolic versatility in extreme environments. Moreover, S. lunaelactis exhibits a complex life cycle with the formation of mycelium and spores, which is characteristic of the Streptomyces genus. This life cycle is not only interesting from a developmental biology perspective but also plays a role in the organism's ability to produce secondary metabolites. In summary, Streptomyces lunaelactis is a microorganism of significant interest due to its unique origin, extensive secondary metabolite production, and potential applications in drug discovery and biotechnology.

Streptomyces lunaelactis is a fascinating actinobacterium known for its unique ability to produce a variety of bioactive compounds, particularly those with antimicrobial properties. This microorganism is part of the larger genus Streptomyces, which is renowned for its role in natural antibiotic production, making it a significant player in pharmaceutical research and development. One of the most interesting aspects of S. lunaelactis is its ability to thrive in extreme environments, which often leads to the discovery of novel secondary metabolites. These metabolites can have potential applications in medicine, agriculture, and biotechnology. The unique ecological niche that S. lunaelactis occupies allows it to produce compounds that may not be found in other closely related species, thus contributing to the diversity of natural products available for drug discovery. Additionally, S. lunaelactis has been studied for its potential in bioremediation, as it can degrade various environmental pollutants. This characteristic not only highlights its ecological importance but also its potential utility in addressing environmental challenges. Furthermore, the genomic studies of S. lunaelactis have revealed insights into its metabolic pathways, which can be harnessed for synthetic biology applications. Researchers are particularly interested in the genetic mechanisms that enable this organism to produce its diverse array of metabolites, paving the way for engineered strains that could produce valuable compounds more efficiently. In summary, Streptomyces lunaelactis stands out due to its antimicrobial properties, extremophilic nature, and biotechnological potential, making it a valuable subject for ongoing research in microbiology and natural product chemistry.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces lunaelactis

NCBI ID

1535768

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/054/555/GCF_003054555.1_ASM305455v1

File for sequence-based predictions:
GCF_003054555.1_ASM305455v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces lunaelactis is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. lunaelactis itself is not primarily associated with human disease, its relevance in antimicrobial production is noteworthy. This species has been studied for its potential to produce novel antibiotics that could combat antimicrobial resistance (AMR), a growing concern in clinical settings. The ability of Streptomyces species to synthesize a wide variety of secondary metabolites makes them a valuable resource in the search for new therapeutic agents. In terms of pathogenicity, S. lunaelactis is generally considered non-pathogenic to humans; however, the genus Streptomyces can occasionally be implicated in opportunistic infections, particularly in immunocompromised individuals. The mechanisms of immune evasion are not well-documented for S. lunaelactis, but related species have been shown to produce enzymes that can degrade host immune factors, potentially aiding in their survival in hostile environments. Furthermore, the ecological role of S. lunaelactis in soil and its interactions with other microorganisms can influence human health indirectly, particularly through its contributions to soil health and the microbiome. The potential for S. lunaelactis to be utilized in probiotic formulations or as a source of novel therapeutics underscores its importance in the field of microbiology and medicine. Overall, while Streptomyces lunaelactis may not be directly linked to specific diseases, its contributions to antibiotic discovery and its ecological significance highlight its relevance in the broader context of human health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces lunaelactis is a species of actinobacteria that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its presence is often noted in tropical and subtropical regions, where the warm and humid conditions favor its growth and metabolic activities. In these soil habitats, S. lunaelactis contributes to nutrient cycling by breaking down complex organic compounds, thus facilitating the availability of nutrients for plants and other organisms. This process is vital for maintaining soil health and fertility, making S. lunaelactis an important player in the terrestrial ecosystem. Additionally, S. lunaelactis is known for its ability to produce various bioactive compounds, which can have significant implications for plant-microbe interactions. These compounds may promote plant growth or provide protection against pathogens, highlighting the potential for symbiotic relationships with plants. Such interactions can enhance the resilience of plant communities in its native habitats. Furthermore, S. lunaelactis exhibits remarkable environmental adaptability, allowing it to survive in varying conditions, including changes in moisture and nutrient availability. This adaptability not only aids in its survival but also enhances its role in bioremediation, where it can help degrade pollutants in contaminated soils. Overall, the ecological niche of Streptomyces lunaelactis is characterized by its essential contributions to soil health, nutrient cycling, and plant interactions, making it a significant organism within its associated biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces lunaelactis is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology and pharmaceutical development. This actinobacterium is recognized for its ability to produce a range of bioactive compounds, including antibiotics and other secondary metabolites, which are crucial in the development of new medications. For instance, the fermentation processes involving Streptomyces lunaelactis can lead to the production of novel antimicrobial agents that are effective against resistant strains of bacteria. In addition to its pharmaceutical potential, Streptomyces lunaelactis plays a role in waste management through its capacity for biodegradation. This organism can break down complex organic materials, making it valuable in the treatment of waste products, particularly in composting and bioremediation efforts. Its enzymatic activity allows it to degrade pollutants, thus contributing to environmental sustainability. Moreover, the metabolic pathways of Streptomyces lunaelactis are being explored for biofuel production. The organism's ability to metabolize various substrates can be harnessed in fermentation processes to produce biofuels, such as ethanol, from agricultural waste. This not only provides a renewable energy source but also aids in reducing waste. Overall, Streptomyces lunaelactis exemplifies the potential of microorganisms in advancing biotechnology, enhancing waste management practices, and contributing to sustainable energy solutions, making it a valuable organism in multiple industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro	google/gemini-pro	google/gemma-7b-it	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	true	true	true	false	false	false	true	true	false	false	false	false	false	false	false	false	true	true	false	false	true	true	true	true	true	true
Biofilm formation	N/A	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	false	true	false	true	true	false	true	false	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true
Host association	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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