Bartonella capreoli

General Information

Bartonella capreoli is a fascinating bacterium that belongs to the genus Bartonella, which is known for its ability to infect a wide range of mammalian hosts. This particular species was first isolated from roe deer (Capreolus capreolus), which is reflected in its name. One of the most intriguing aspects of B. capreoli is its zoonotic potential, meaning it can be transmitted from animals to humans, making it a subject of significant interest in the field of infectious diseases and public health. B. capreoli is part of a larger group of Bartonella species that are known to cause chronic infections in their hosts. These infections can lead to a variety of clinical manifestations, ranging from mild symptoms to more severe conditions, depending on the host's immune response and the specific Bartonella species involved. The ability of B. capreoli to persist in the host for extended periods without causing immediate, severe disease is a key characteristic that makes it particularly interesting for researchers studying host-pathogen interactions and chronic bacterial infections. Another noteworthy feature of B. capreoli is its genetic diversity and adaptability. This bacterium has a relatively large genome compared to other Bartonella species, which may contribute to its ability to infect different hosts and adapt to various environmental conditions. The study of B. capreoli's genome can provide valuable insights into the mechanisms of bacterial evolution, host specificity, and pathogenicity. In addition to its medical and scientific importance, B. capreoli also has ecological significance. As a pathogen of wildlife, it plays a role in the health and population dynamics of its animal hosts. Understanding the ecology of B. capreoli can help in the management of wildlife diseases and the conservation of affected species. Overall, Bartonella capreoli is a remarkable organism that offers numerous opportunities for research in microbiology, infectious diseases, genomics, and ecology. Its ability to bridge the gap between wildlife and human health underscores the importance of studying zoonotic pathogens and their impact on global health.

Bartonella capreoli is a fascinating bacterium primarily associated with goats and sheep, making it particularly interesting for veterinary microbiology and zoonotic disease research. This organism is part of the genus Bartonella, which is known for its role in various diseases affecting both animals and humans. One of the most notable aspects of B. capreoli is its potential to cause infections in livestock, which can lead to significant economic losses in the agricultural sector. Understanding the pathogenic mechanisms of B. capreoli is crucial for developing effective control strategies and improving animal health. The bacterium is transmitted through ectoparasites, such as fleas and ticks, which makes it a subject of interest in studies related to vector-borne diseases. This transmission route highlights the importance of understanding the ecology of B. capreoli and its interactions with both hosts and vectors. From a research perspective, B. capreoli serves as a model organism for studying the broader Bartonella genus, which includes several species known to infect humans, such as Bartonella henselae, the causative agent of cat scratch fever. Investigating the genetic and biochemical pathways of B. capreoli can provide insights into the evolution and adaptation of Bartonella species, enhancing our understanding of their pathogenicity and host interactions. Moreover, the study of B. capreoli can contribute to the development of diagnostic tools and vaccines for livestock, which is essential for preventing outbreaks and ensuring food security. The unique ecological niche of B. capreoli in ruminants underscores its significance in both veterinary and public health contexts.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Alphaproteobacteria

Order: Hyphomicrobiales

Family: Bartonellaceae

Genus: Bartonella

Species: Bartonella capreoli

NCBI ID

155192

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/902/813/205/GCA_902813205.1_Bartonella_capreoli_DSM_21569

File for sequence-based predictions:
GCA_902813205.1_Bartonella_capreoli_DSM_21569_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Bartonella capreoli is a member of the genus Bartonella, which is known for its association with various zoonotic diseases. This particular species has been identified in goats and is of interest due to its potential implications in human health and disease associations. While Bartonella capreoli has not been extensively studied in humans, it is hypothesized to be a potential pathogen that could cause infections similar to those caused by other Bartonella species, such as Bartonella henselae, which is known to cause cat scratch fever and Bartonellosis in humans. Pathogenicity is a significant concern, as Bartonella species are known to exhibit immune evasion strategies that allow them to persist in the host. They can evade the immune response by residing within red blood cells and endothelial cells, making them difficult to detect and treat. This characteristic raises concerns about the potential for Bartonella capreoli to cause chronic infections or to be involved in co-infections with other pathogens. Antimicrobial resistance is another area of concern, as some Bartonella species have shown resistance to common antibiotics, complicating treatment options. The potential for Bartonella capreoli to develop similar resistance mechanisms is an important consideration for public health. In terms of medical applications, while there are no specific vaccines or therapeutics currently available for Bartonella capreoli, understanding its role in zoonotic transmission could inform future strategies for prevention and control of Bartonella-related diseases. Further research is needed to clarify its clinical significance and to determine if it poses a direct risk to human health, especially in individuals with compromised immune systems or those in close contact with infected animals.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Bartonella capreoli is a bacterium primarily associated with the wildlife habitats of ruminants, particularly in regions where these animals are prevalent. This microorganism is often found in the blood of its hosts, such as deer and goats, indicating its adaptation to the terrestrial ecosystems where these animals thrive. The bacterium is transmitted through ectoparasites, notably ticks, which play a crucial role in its life cycle and distribution. In these grassland and forest biomes, Bartonella capreoli interacts with its environment by influencing the health of its host species. It can cause various diseases, which may affect the population dynamics of ruminants, thereby impacting the overall biodiversity of these ecosystems. The presence of this bacterium can also have implications for human health, as it can be transmitted to humans through contact with infected animals or their ectoparasites. Furthermore, Bartonella capreoli exhibits a form of symbiosis with its hosts, where it can persist without causing immediate harm, allowing it to maintain a stable presence within the host population. This relationship underscores the importance of understanding the ecological roles of such microorganisms in maintaining the balance of their respective biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Bartonella capreoli has garnered attention for its potential applications in various industrial sectors, particularly in biotechnology and pharmaceutical development. This organism is known to be associated with livestock, particularly goats, and its study has implications for understanding zoonotic diseases. In the realm of pharmaceutical development, Bartonella capreoli is significant due to its role in the study of pathogenic mechanisms and the development of vaccines or treatments for diseases caused by related species. Research into its genetic makeup and virulence factors can lead to advancements in disease management strategies. In terms of biotechnology, Bartonella capreoli can be utilized in the development of diagnostic tools for detecting infections in animals, which is crucial for maintaining livestock health and preventing the spread of zoonotic diseases to humans. The organism's unique metabolic pathways may also be explored for the production of specific biomolecules or enzymes that could have industrial relevance. While Bartonella capreoli is not directly linked to processes like fermentation or biodegradation, its study contributes to a broader understanding of microbial interactions in agricultural settings, which can indirectly influence waste management practices. Understanding how this organism interacts with its environment can lead to improved strategies for managing animal waste and reducing the risk of disease transmission. Overall, while the direct industrial applications of Bartonella capreoli may be limited, its role in biotechnology and pharmaceutical development highlights its importance in advancing health and safety in agricultural practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 11

LLM predicted phenotypes: 2

Phenotype	High-quality annotation	google/gemini-pro	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	anthropic/claude-3-haiku:beta	google/gemma-7b-it	mistralai/mistral-7b-instruct	meta-llama/llama-3-70b-instruct:nitro	openchat/openchat-7b	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain variable ✗	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 3 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	N/A	N/A	N/A	N/A	alpha ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

Back to Search