Mycobacterium grossiae

General Information

Mycobacterium grossiae is a species of bacteria within the genus Mycobacterium, which is renowned for its complex and lipid-rich cell wall. This characteristic cell wall structure contributes to its resilience and ability to survive in harsh environments. One of the most intriguing aspects of M. grossiae is its potential role in environmental bioremediation. The species has shown promise in breaking down complex organic pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, M. grossiae is of interest due to its unique metabolic pathways, which differ significantly from those of other bacteria. These pathways allow it to utilize a wide range of substrates, including some that are typically resistant to microbial degradation. This metabolic versatility not only underscores its ecological importance but also opens up possibilities for industrial applications, such as the production of biofuels and bioplastics. Furthermore, the study of M. grossiae can provide insights into the evolution and adaptation mechanisms of mycobacteria, contributing to our broader understanding of microbial diversity and resilience. Overall, the unique characteristics of Mycobacterium grossiae make it a fascinating subject for scientific research, with potential applications in environmental science, industry, and evolutionary biology.

Mycobacterium grossiae is a fascinating species within the genus Mycobacterium, known for its unique ecological niche and potential applications in biotechnology and medicine. This organism is primarily isolated from soil and has been studied for its ability to degrade complex organic compounds, making it a valuable player in bioremediation efforts. Its metabolic versatility allows it to thrive in diverse environments, which is particularly interesting for researchers focused on environmental microbiology. One of the standout features of M. grossiae is its production of bioactive compounds, which have shown promise in pharmaceutical applications. These compounds may possess antimicrobial properties, providing a potential avenue for the development of new antibiotics in an era of increasing antibiotic resistance. Additionally, M. grossiae has been noted for its unique lipid composition, which is characteristic of the Mycobacterium genus. This lipid profile not only contributes to its survival in harsh conditions but also makes it a subject of interest in studies related to cell membrane biology and the development of novel drug delivery systems. Overall, Mycobacterium grossiae represents a significant area of research due to its ecological importance, potential biotechnological applications, and contributions to our understanding of microbial metabolism and antibiotic development.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium grossiae

NCBI ID

1552759

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/008/329/645/GCF_008329645.1_ASM832964v1

File for sequence-based predictions:
GCF_008329645.1_ASM832964v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycobacterium grossiae is a less commonly discussed member of the Mycobacterium genus, which is primarily known for its pathogenic species such as Mycobacterium tuberculosis. While M. grossiae has not been extensively studied, it is important to consider its potential clinical implications. This organism has been associated with infections in immunocompromised individuals, particularly those with underlying health conditions that may predispose them to opportunistic infections. Pathogenicity may arise from its ability to evade the immune response, although specific mechanisms remain to be fully elucidated. Furthermore, there is a growing concern regarding antimicrobial resistance among mycobacterial species, and while specific resistance patterns for M. grossiae are not well-documented, the general trend of increasing resistance in the Mycobacterium genus raises alarms for potential treatment challenges. As research continues, it is crucial to monitor the clinical relevance of M. grossiae in the context of emerging infections and its role in the broader spectrum of mycobacterial diseases.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycobacterium grossiae is primarily associated with soil environments and decaying organic matter. This microorganism thrives in nutrient-rich substrates, often found in areas with high levels of organic decomposition. Its ecological niche is characterized by the ability to degrade complex organic compounds, contributing to nutrient cycling within the ecosystem. In these soil habitats, Mycobacterium grossiae plays a crucial role in the breakdown of organic materials, which enhances soil fertility and promotes plant growth. The organism is known for its ability to form symbiotic relationships with various soil-dwelling organisms, including fungi and other bacteria, facilitating a network of nutrient exchange and enhancing the overall health of the soil microbiome. Additionally, Mycobacterium grossiae exhibits remarkable environmental adaptability, allowing it to survive in varying conditions, including fluctuations in moisture and temperature. This adaptability enables it to colonize diverse habitats, from temperate forests to grasslands, where it contributes to the ecological balance by participating in the decomposition process and influencing soil structure. Overall, Mycobacterium grossiae is an essential component of its biome, demonstrating the interconnectedness of microbial life and its impact on ecosystem dynamics.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycobacterium grossiae has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. One notable application is its role in biodegradation, where Mycobacterium grossiae can break down complex organic compounds, making it valuable for the treatment of contaminated environments. This capability is particularly useful in the remediation of sites polluted with hydrocarbons and other toxic substances, contributing to more sustainable waste management practices. In the realm of biofuel production, Mycobacterium grossiae has been studied for its ability to metabolize certain substrates that can be converted into biofuels. The organism's enzymatic activity can facilitate the breakdown of lignocellulosic biomass, which is a critical step in the production of second-generation biofuels. This process often involves fermentation, where the microorganism converts sugars derived from biomass into ethanol or other biofuels, thus supporting renewable energy initiatives. Furthermore, Mycobacterium grossiae has potential in pharmaceutical development due to its unique metabolic pathways. Research has indicated that it may produce bioactive compounds that could be harnessed for drug development, particularly in the search for new antibiotics or therapeutic agents. The organism's ability to synthesize complex molecules through enzyme production is of particular interest in this context, as it may lead to the discovery of novel pharmaceuticals. Overall, Mycobacterium grossiae represents a promising candidate for various industrial applications, leveraging its natural capabilities in biodegradation, fermentation, and enzyme production to address environmental challenges and contribute to advancements in biotechnology and medicine.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-pro	mistralai/mistral-7b-instruct	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	openai/gpt-4	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openchat/openchat-7b	openchat/openchat-7b	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	true	true	false	false	true	true	true	false	false	false	false	true	false	false	true	true	false	false	true	true	true	true	false	false	true	true
Biofilm formation	N/A	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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