Kribbella capetownensis

General Information

Kribbella capetownensis is a fascinating microorganism belonging to the genus Kribbella. This species was first isolated from soil samples collected in Cape Town, South Africa, which is reflected in its name. One of the most intriguing aspects of K. capetownensis is its ability to thrive in diverse and often extreme environmental conditions, making it a subject of interest for studies on microbial ecology and environmental microbiology. Unique Metabolic Capabilities: K. capetownensis exhibits a broad range of enzymatic activities, which allows it to degrade various complex organic compounds. This metabolic versatility is particularly valuable for bioremediation efforts, where the organism can be employed to break down pollutants in contaminated environments. Secondary Metabolite Production: Another notable feature of K. capetownensis is its potential to produce secondary metabolites with antimicrobial properties. These compounds are of significant interest in the search for new antibiotics, especially given the rising concern over antibiotic resistance. The ability of K. capetownensis to produce such bioactive compounds makes it a promising candidate for pharmaceutical research. Genomic Insights: The genome of K. capetownensis has been sequenced, providing valuable insights into its genetic makeup and the pathways involved in its unique metabolic processes. This genomic information is crucial for biotechnological applications, including the engineering of strains for specific industrial processes. In summary, Kribbella capetownensis stands out due to its environmental resilience, metabolic diversity, and potential for secondary metabolite production. These characteristics not only make it an interesting subject for scientific research but also highlight its potential applications in bioremediation and drug discovery.

Kribbella capetownensis is a fascinating actinobacterium that was first isolated from a soil sample in Cape Town, South Africa. This organism is particularly interesting due to its unique ecological niche and its potential applications in biotechnology and pharmaceuticals. The genus Kribbella is known for its ability to produce a variety of bioactive compounds, which makes K. capetownensis a valuable candidate for research in natural product chemistry. One of the standout features of K. capetownensis is its metabolic versatility, allowing it to thrive in diverse environments. This adaptability is crucial for its survival in nutrient-poor soils, where it can outcompete other microorganisms. The ability to utilize various carbon sources enhances its potential for bioremediation, particularly in contaminated environments. Moreover, K. capetownensis has been studied for its antimicrobial properties, which could lead to the discovery of new antibiotics. The increasing concern over antibiotic resistance makes the search for novel antimicrobial agents more urgent, and actinobacteria like K. capetownensis are at the forefront of this research. In addition to its antimicrobial potential, this species is also of interest for its role in soil health and nutrient cycling. By contributing to the breakdown of organic matter, K. capetownensis plays a significant role in maintaining soil fertility and ecosystem balance. Overall, Kribbella capetownensis exemplifies the rich biodiversity found in soil microorganisms and highlights the importance of studying such organisms for their ecological roles and potential benefits to human health and the environment.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Propionibacteriales

Family: Kribbellaceae

Genus: Kribbella

Species: Kribbella capetownensis

NCBI ID

1572659

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/004/331/485/GCF_004331485.1_ASM433148v1

File for sequence-based predictions:
GCF_004331485.1_ASM433148v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Kribbella capetownensis is a member of the Actinobacteria phylum and has been identified in various environmental samples, including soil and marine environments. Its clinical relevance is still being explored, but it has been associated with certain infections in immunocompromised patients. Notably, it has been isolated from clinical specimens, suggesting a potential role in opportunistic pathogenicity. Clinical implications of Kribbella capetownensis include its potential to cause infections in individuals with weakened immune systems, although specific disease associations are not yet well-documented. The organism's ability to survive in diverse environments may indicate a level of antimicrobial resistance, which is a growing concern in clinical microbiology. Furthermore, the organism's interactions with the human body and its immune evasion strategies are not fully understood, but its presence in clinical settings warrants further investigation. As research progresses, Kribbella capetownensis may reveal more about its role in human health and disease, particularly in the context of opportunistic infections and its potential use in biotechnological applications.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Kribbella capetownensis is a species of actinobacteria that has been primarily isolated from marine environments, particularly from sediments and seawater. This microorganism thrives in coastal ecosystems, where it plays a significant role in nutrient cycling and organic matter decomposition. Its presence in these habitats contributes to the overall health of the marine biome by facilitating the breakdown of complex organic materials, thus releasing essential nutrients back into the ecosystem. In addition to its role in nutrient cycling, Kribbella capetownensis exhibits notable interactions with other microorganisms and marine organisms. It is known to engage in symbiotic relationships with various marine invertebrates, potentially aiding in their growth and health through the production of bioactive compounds. These compounds can have antimicrobial properties, which may help protect host organisms from pathogens. Furthermore, this bacterium demonstrates remarkable environmental adaptability, allowing it to thrive in varying conditions of salinity and temperature typical of coastal waters. Its ability to withstand these fluctuations is crucial for its survival and ecological function in dynamic marine environments. Overall, Kribbella capetownensis is an important player in the marine biome, contributing to both the ecological balance and the health of its surrounding environment.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Kribbella capetownensis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its unique metabolic capabilities. This organism is known for its ability to produce a range of bioactive compounds, which can be harnessed in the development of pharmaceuticals. For instance, the secondary metabolites produced by Kribbella capetownensis have been investigated for their antimicrobial properties, making them valuable in the creation of new antibiotics. In the realm of waste management, Kribbella capetownensis has demonstrated effective biodegradation capabilities. It can break down complex organic materials, which is particularly useful in the treatment of wastewater and the remediation of contaminated environments. This process not only helps in reducing pollution but also contributes to the recycling of nutrients back into the ecosystem. Furthermore, this microorganism has potential applications in biofuel production. Through fermentation processes, Kribbella capetownensis can convert organic substrates into biofuels, providing a sustainable alternative to fossil fuels. The efficiency of its metabolic pathways in converting biomass into energy-rich compounds is an area of ongoing research. Overall, Kribbella capetownensis represents a promising candidate for various industries, particularly in pharmaceutical development, waste treatment, and renewable energy production, showcasing its versatility and importance in modern biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	anthropic/claude-3.5-sonnet	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	google/gemini-pro	google/gemini-pro	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	anaerobic ✗	anaerobic ✗	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	false	true	true	true	true	false	true	true	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true
Animal pathogenicity	N/A	false	false	false	true	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	false	true	true	true	true	false	true	false	false	true	true	false	false	false	false	false	false	false	false	true	true	true	true	true	true
Host association	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	beta	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus

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