Williamsia herbipolensis

General Information

Williamsia herbipolensis is a fascinating microorganism belonging to the genus Williamsia. This genus is part of the family Nocardiaceae, which includes several species known for their complex and diverse metabolic capabilities. One of the most intriguing aspects of W. herbipolensis is its ability to degrade a wide range of organic compounds, making it a subject of interest in environmental microbiology and bioremediation research. Key Characteristics: Williamsia herbipolensis is notable for its metabolic versatility. It can utilize various hydrocarbons and other complex organic molecules as carbon sources, which is particularly valuable for the breakdown of environmental pollutants. This capability positions W. herbipolensis as a potential candidate for bioremediation efforts, especially in contaminated soil and water environments. Another interesting feature of W. herbipolensis is its production of secondary metabolites. These compounds can have antimicrobial properties, which opens up possibilities for discovering new antibiotics or other bioactive molecules. The study of these secondary metabolites can provide insights into novel chemical structures and mechanisms of action, contributing to the field of natural product chemistry. From a taxonomic perspective, W. herbipolensis adds to the diversity of the Nocardiaceae family, which is known for its members' complex life cycles and morphological diversity. The genus Williamsia itself is relatively less studied compared to other genera in the family, making W. herbipolensis an exciting subject for further taxonomic and phylogenetic studies. In summary, Williamsia herbipolensis is a microorganism of significant interest due to its environmental adaptability, bioremediation potential, and secondary metabolite production. These characteristics not only make it valuable for practical applications but also for advancing our understanding of microbial diversity and metabolic capabilities.

Williamsia herbipolensis is a fascinating bacterium that belongs to the family of Microbacteriaceae. This organism is particularly interesting due to its unique ecological niche and its ability to thrive in extreme environments, specifically in herbaceous plant habitats. Its isolation from soil samples in the Antarctic region highlights its resilience and adaptability to harsh conditions, making it a valuable subject for studies on extremophiles and microbial ecology. One of the most notable characteristics of Williamsia herbipolensis is its potential for biotechnological applications. Research has indicated that this bacterium possesses enzymes that can degrade complex organic compounds, which could be harnessed for bioremediation efforts, particularly in the breakdown of pollutants in soil and water. This capability positions W. herbipolensis as a promising candidate for environmental cleanup strategies. Additionally, the genomic analysis of Williamsia herbipolensis has revealed a rich repertoire of genes that may contribute to its survival in nutrient-poor environments. The study of its metabolic pathways can provide insights into microbial adaptation and evolution, offering a window into how life can persist in extreme conditions. This makes W. herbipolensis not only a subject of interest for microbiologists but also for researchers focused on climate change and environmental sustainability. In summary, Williamsia herbipolensis stands out due to its ecological significance, potential biotechnological applications, and its role in understanding microbial life in extreme environments. Its study could lead to advancements in both environmental science and biotechnology, making it a valuable organism in contemporary research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Nocardiaceae

Genus: Williamsia

Species: Williamsia herbipolensis

NCBI ID

1603258

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/036/153/515/GCF_036153515.1_ASM3615351v1

File for sequence-based predictions:
GCF_036153515.1_ASM3615351v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Williamsia herbipolensis is a Gram-positive bacterium that has been isolated from various environmental sources, including soil and plant material. While it is not commonly associated with human disease, its clinical relevance has been noted in specific contexts. Infections caused by Williamsia herbipolensis are rare but can occur, particularly in immunocompromised individuals. The organism has been identified in cases of opportunistic infections, highlighting the importance of understanding its pathogenic potential in vulnerable populations. One of the notable aspects of Williamsia herbipolensis is its potential for antimicrobial resistance. Studies have indicated that this organism may possess resistance mechanisms that could complicate treatment options, particularly in cases where it is involved in polymicrobial infections. This underscores the need for ongoing surveillance and research to better understand its resistance profiles and implications for therapy. In terms of immune evasion strategies, Williamsia herbipolensis may utilize various mechanisms to avoid detection and clearance by the host immune system, although specific details on these strategies remain limited. Its environmental origins suggest that it may have adaptations that allow it to survive in diverse conditions, which could translate to its ability to persist in human hosts under certain circumstances. Overall, while Williamsia herbipolensis is not a primary pathogen, its role in opportunistic infections, potential for antimicrobial resistance, and interactions with the human immune system warrant further investigation to fully elucidate its clinical implications.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Williamsia herbipolensis has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its unique metabolic capabilities. This organism is known for its ability to thrive in extreme environments, which can be harnessed for biodegradation processes, particularly in the breakdown of complex organic compounds in contaminated sites. In the realm of waste management, Williamsia herbipolensis can be employed in bioremediation efforts, where it aids in the detoxification of hazardous waste by metabolizing pollutants. Its enzymatic activity is particularly valuable in this context, as it can produce specific enzymes that facilitate the degradation of toxic substances, making it a key player in environmental cleanup initiatives. Moreover, Williamsia herbipolensis has potential applications in biofuel production. Its metabolic pathways can be exploited in fermentation processes to convert biomass into biofuels, such as ethanol. This capability not only contributes to sustainable energy solutions but also aligns with the growing demand for renewable energy sources. In the pharmaceutical development sector, the organism's unique biochemical properties may lead to the discovery of novel compounds with therapeutic potential. Research into its secondary metabolites could yield new drugs or enhance existing treatments, showcasing its versatility in the pharmaceutical industry. Overall, Williamsia herbipolensis represents a promising candidate for various industrial applications, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development, due to its robust metabolic capabilities and adaptability to extreme conditions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	mistralai/mistral-7b-instruct	google/gemini-flash-1.5	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemini-pro	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain variable ✗	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerotolerant ✗	N/A	aerotolerant ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	false	true	true	false	true	false	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	false	true	false	true	true	false	true	false	false	false	false	false	false	false	false	true	true	true	true	true	true	false	false	false	false
Host association	N/A	true	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	true	true	false	false	true	true	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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