Streptomyces albiflavescens

General Information

Streptomyces albiflavescens is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. albiflavescens is its ability to produce a wide array of antibiotics, making it a valuable subject of study in pharmaceutical research. This species is part of the Actinobacteria phylum, which is known for its high G+C content in DNA, contributing to its complex and diverse metabolic capabilities. Streptomyces albiflavescens forms branching filaments that resemble fungal mycelia, a trait common to the genus, which allows it to efficiently colonize and decompose organic matter in soil environments. This decomposition ability is crucial for nutrient cycling in ecosystems, highlighting its ecological importance. The production of bioactive compounds by S. albiflavescens includes not only antibiotics but also antifungal agents, antitumor agents, and immunosuppressants. These compounds have significant therapeutic potential and are the subject of extensive research for drug development. The genetic and enzymatic pathways involved in the biosynthesis of these compounds are of particular interest, as understanding them can lead to the discovery of new drugs and the improvement of existing ones. Additionally, S. albiflavescens exhibits a unique pigmentation, often producing yellowish to white colonies, which can be a useful phenotypic marker in laboratory identification and differentiation from other Streptomyces species. The organism's ability to thrive in diverse environmental conditions and its resilience to various stress factors make it a robust model for studying microbial adaptation and survival mechanisms. In summary, Streptomyces albiflavescens is a microorganism of significant interest due to its extensive secondary metabolite production, ecological role in soil health, and potential applications in biotechnology and medicine. Its study not only advances our understanding of microbial ecology and evolution but also holds promise for the development of novel therapeutic agents.

Streptomyces albiflavescens is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is part of the larger genus Streptomyces, which is renowned for its prolific secondary metabolite production, including antibiotics, antifungals, and immunosuppressants. What sets S. albiflavescens apart is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic applications. One of the most interesting aspects of S. albiflavescens is its ability to thrive in diverse environments, which contributes to its genetic diversity and the potential for discovering novel bioactive substances. Researchers have isolated various metabolites from this species, some of which exhibit significant antimicrobial activity against a range of pathogens, including resistant strains. This characteristic makes S. albiflavescens a prime candidate for bioprospecting in the search for new antibiotics, especially in the face of rising antibiotic resistance. Additionally, S. albiflavescens has been studied for its role in soil health and plant growth promotion, as it can produce enzymes that degrade complex organic materials, thus contributing to nutrient cycling in ecosystems. Its ecological significance and potential applications in agriculture further enhance its value in research. Overall, Streptomyces albiflavescens stands out as a promising organism for both pharmaceutical and environmental studies, highlighting the importance of actinobacteria in biotechnology and natural product discovery.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces albiflavescens

NCBI ID

1623582

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/645/835/GCA_014645835.1_ASM1464583v1

File for sequence-based predictions:
GCA_014645835.1_ASM1464583v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces albiflavescens is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. albiflavescens itself is not commonly associated with human disease, its relatives have been implicated in various infections and have demonstrated notable pathogenicity in certain contexts. Clinical relevance arises primarily from its potential applications in medicine rather than direct pathogenic effects on humans. One of the most important aspects of S. albiflavescens is its ability to produce a variety of secondary metabolites, including antibiotics such as streptomycin and other compounds that may have therapeutic potential. This makes it a valuable organism in the field of pharmaceutical development and biotechnology. In terms of immune evasion, while specific mechanisms for S. albiflavescens are not well-documented, many Streptomyces species have developed strategies to survive in competitive environments, which may include the production of antimicrobial compounds that inhibit the growth of competing microorganisms. Furthermore, the organism's role in soil ecosystems contributes to its relevance in environmental health, as it helps in the degradation of organic materials and the cycling of nutrients. This ecological function can indirectly influence human health by maintaining soil quality and promoting agricultural productivity. Overall, while Streptomyces albiflavescens is not a primary pathogen, its contributions to antibiotic production and potential therapeutic applications underscore its importance in clinical microbiology and pharmacology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces albiflavescens is a species of actinobacteria commonly found in various terrestrial environments, particularly in soil and decaying organic matter. This microorganism thrives in nutrient-rich environments where it plays a crucial role in the decomposition of organic materials, contributing to nutrient cycling within the ecosystem. Its ability to produce a wide range of bioactive compounds makes it significant in the soil microbiome, where it interacts with other microorganisms and plants, often promoting plant health through antibiotic production and nutrient solubilization. In addition to its role in decomposition, Streptomyces albiflavescens is known for its symbiotic relationships with plants. It can enhance plant growth by providing essential nutrients and protecting against pathogens, showcasing its importance in agricultural ecosystems. The organism's adaptability to various pH levels and moisture conditions allows it to thrive in diverse habitats, from arid soils to humid forest floors. Overall, Streptomyces albiflavescens exemplifies the intricate relationships within its biomes, contributing to both ecological balance and agricultural productivity.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces albiflavescens has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces albiflavescens has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and reducing environmental pollution. Its enzymatic activity allows it to degrade various pollutants, making it a valuable asset in bioremediation efforts. Furthermore, this microorganism has potential applications in biofuel production. By participating in fermentation processes, it can convert biomass into biofuels, contributing to sustainable energy solutions. The enzymes produced by Streptomyces albiflavescens can also enhance the efficiency of biomass conversion, making it a promising candidate for future biofuel technologies. Overall, Streptomyces albiflavescens stands out as a versatile microorganism with applications spanning pharmaceutical development, waste treatment, and bioenergy, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	N/A	false	false	false	true	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	false	false	true	true	true	true	true	false	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	N/A	true	false	true	false	true	true	true	false	false	false	false	false	false	false	false	true	true	false	false	false	false	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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