Microbacterium hominis

General Information

Microbacterium hominis is a fascinating microorganism belonging to the genus Microbacterium. This genus is known for its diverse metabolic capabilities and environmental adaptability. One of the most intriguing aspects of Microbacterium hominis is its potential role in human health and disease. Although it is not a common pathogen, it has been isolated from clinical samples, suggesting it may have opportunistic pathogenic potential under certain conditions. Another noteworthy characteristic of Microbacterium hominis is its ability to degrade complex organic compounds. This makes it a subject of interest in bioremediation research, where it could be utilized to break down pollutants in contaminated environments. Additionally, the metabolic versatility of this microorganism allows it to thrive in a variety of ecological niches, from soil to water systems, further underscoring its environmental significance. From a biotechnological perspective, Microbacterium hominis holds promise due to its production of unique enzymes and secondary metabolites. These biochemical products could have applications in industrial processes, pharmaceuticals, and agriculture. The study of these compounds is ongoing, and they may lead to the development of new antibiotics or other therapeutic agents. In summary, Microbacterium hominis is a microorganism of considerable interest due to its potential clinical relevance, environmental adaptability, and biotechnological applications. Its diverse metabolic capabilities and ability to produce unique biochemical compounds make it a valuable subject for further research.

Microbacterium hominis is a member of the genus Microbacterium, which is known for its diverse metabolic capabilities and ecological versatility. This organism is particularly interesting due to its ability to degrade a variety of complex organic compounds, making it valuable in bioremediation efforts. Its enzymatic pathways allow it to break down pollutants, which can be crucial in environmental cleanup processes. One of the unique aspects of M. hominis is its association with human skin and mucosal surfaces, suggesting a potential role in the human microbiome. This relationship raises questions about its impact on human health and disease, particularly in understanding how skin-associated microbes contribute to skin conditions or overall health. Additionally, Microbacterium species, including M. hominis, are known for their antimicrobial properties, which have garnered interest in pharmaceutical research. The potential for discovering novel compounds that can be used in antibiotic development is a significant area of study, especially in the context of rising antibiotic resistance. Overall, Microbacterium hominis stands out not only for its ecological roles but also for its implications in human health and its potential applications in biotechnology and medicine.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micrococcales

Family: Microbacteriaceae

Genus: Microbacterium

Species: Microbacterium hominis

NCBI ID

162426

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/725/695/GCA_014725695.1_ASM1472569v1

File for sequence-based predictions:
GCA_014725695.1_ASM1472569v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Microbacterium hominis is a member of the genus Microbacterium, which is known for its environmental presence and potential clinical significance. While M. hominis is not commonly associated with severe infections, it has been implicated in certain infections in immunocompromised patients, particularly those with underlying health conditions. Clinical relevance includes its role as an opportunistic pathogen, where it can cause soft tissue infections, bacteremia, and endocarditis in susceptible individuals. One of the notable aspects of M. hominis is its antimicrobial resistance profile. It has shown resistance to multiple antibiotics, which complicates treatment options for infections it may cause. This resistance is particularly concerning in hospital settings where patients may be more vulnerable to opportunistic infections. In terms of immune evasion, M. hominis may employ strategies that allow it to persist in the human body, although specific mechanisms are not as well-documented as those of more pathogenic bacteria. Its presence in clinical specimens often raises questions about its role as a contaminant versus a true pathogen, necessitating careful interpretation of laboratory results. Currently, there are no widely recognized medical applications of M. hominis such as probiotics or vaccines, but its study contributes to the broader understanding of the Microbacterium genus and its interactions with human health. Overall, while M. hominis is not a primary pathogen, its potential to cause disease in vulnerable populations and its resistance patterns warrant attention in clinical microbiology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Microbacterium hominis is a species of bacteria that is primarily associated with human environments, particularly within the human microbiome. This organism is commonly found on the skin and in various mucosal surfaces, playing a significant role in maintaining the balance of microbial communities in these areas. Its presence is often linked to the epidermal layer of the skin, where it contributes to the overall health of the skin microbiota by competing with pathogenic organisms and producing antimicrobial substances. In addition to its role on the skin, Microbacterium hominis can also be found in soil and water environments, where it participates in the degradation of organic matter. This ability to break down complex compounds highlights its importance in nutrient cycling within these ecosystems. The organism exhibits a remarkable capacity for environmental adaptation, allowing it to thrive in varying conditions, including different pH levels and temperatures. Notably, Microbacterium hominis has been observed to engage in symbiotic relationships with other microorganisms, enhancing the resilience of microbial communities in its habitats. Its interactions with other bacteria can lead to the production of beneficial metabolites, which further supports the health of the surrounding ecosystem. Overall, Microbacterium hominis plays a crucial role in both human-associated environments and broader ecological contexts, contributing to the stability and functionality of microbial communities.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Microbacterium hominis has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to thrive in diverse environments, which makes it a candidate for several biotechnological processes. In biotechnology, Microbacterium hominis is involved in fermentation processes, where it can be utilized to produce valuable metabolites. These metabolites can serve as precursors for pharmaceuticals or as bioactive compounds in food and cosmetic industries. In the realm of waste management, Microbacterium hominis has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This property is beneficial for the treatment of wastewater and the remediation of contaminated environments, as it can help in the degradation of pollutants and the recycling of nutrients. Furthermore, in pharmaceutical development, the enzymatic activities of Microbacterium hominis can be harnessed for the production of specific enzymes that are crucial in drug synthesis and formulation. The organism's ability to produce enzymes that catalyze various biochemical reactions can lead to more efficient and sustainable methods of drug production. Overall, Microbacterium hominis presents a versatile profile for industrial applications, particularly in processes such as fermentation, biodegradation, and enzyme production, making it a valuable organism in modern biotechnology and environmental management.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	mistralai/mistral-7b-instruct	meta-llama/llama-3-70b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	google/gemma-7b-it	google/gemma-7b-it	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openchat/openchat-7b	openchat/openchat-7b	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus	bacillus	bacillus

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