Micromonospora craterilacus

General Information

Micromonospora craterilacus is a fascinating microorganism belonging to the genus Micromonospora, which is well-known for its prolific production of bioactive compounds. This particular species was isolated from a unique and extreme environment, specifically a volcanic crater lake, which contributes to its intriguing characteristics and potential applications. One of the most notable features of Micromonospora craterilacus is its ability to produce a wide array of secondary metabolites. These compounds often have significant antibiotic, antifungal, and anticancer properties, making this species a valuable subject for pharmaceutical research. The unique environmental conditions of its habitat may have driven the evolution of novel metabolic pathways, leading to the synthesis of these bioactive molecules. Additionally, Micromonospora craterilacus exhibits a remarkable adaptability to extreme conditions, such as high temperatures and varying pH levels, which are typical of volcanic crater lakes. This adaptability not only highlights the organism's resilience but also suggests potential applications in biotechnology, particularly in processes that require robust microbial agents capable of withstanding harsh industrial conditions. The genetic makeup of Micromonospora craterilacus is another area of interest. Genomic studies have revealed a wealth of genes associated with the biosynthesis of complex natural products. These genes can be harnessed through genetic engineering to produce novel compounds or enhance the yield of existing ones, further underscoring the species' biotechnological potential. In summary, Micromonospora craterilacus is a microorganism of significant interest due to its production of bioactive compounds, adaptability to extreme environments, and genetic potential for biotechnological applications. Its unique origin and capabilities make it a valuable subject for ongoing and future research in various scientific fields.

Micromonospora craterilacus is a fascinating actinobacterium that has garnered attention due to its unique ecological niche and potential biotechnological applications. This microorganism is primarily isolated from soil environments, particularly in areas with volcanic activity, which contributes to its distinctive metabolic capabilities. Its ability to thrive in extreme conditions makes it a subject of interest for researchers studying extremophiles and their adaptations. One of the most notable characteristics of Micromonospora craterilacus is its production of bioactive compounds, including antibiotics and other secondary metabolites. These compounds have significant implications for pharmaceutical research, particularly in the search for new antimicrobial agents. The genus Micromonospora is known for its rich history of antibiotic discovery, and M. craterilacus adds to this legacy with its potential to yield novel compounds that could combat resistant strains of bacteria. Additionally, this organism exhibits a unique morphological structure, characterized by filamentous growth patterns that are typical of actinobacteria. Such structures are not only interesting from a taxonomic perspective but also play a role in its ecological interactions and nutrient cycling within its habitat. In summary, Micromonospora craterilacus stands out due to its extreme habitat, potential for antibiotic production, and unique morphological features, making it a valuable organism for both ecological studies and biotechnological applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micromonosporales

Family: Micromonosporaceae

Genus: Micromonospora

Species: Micromonospora craterilacus

NCBI ID

1655439

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/236/315/GCF_003236315.1_ASM323631v1

File for sequence-based predictions:
GCF_003236315.1_ASM323631v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Micromonospora craterilacus is a member of the genus Micromonospora, which is known for its role in the production of various bioactive compounds, including antibiotics. This microorganism has been studied for its potential in antimicrobial therapy, particularly due to its ability to produce substances that can inhibit the growth of pathogenic bacteria. Clinical implications of Micromonospora craterilacus include its potential use in treating infections caused by antibiotic-resistant strains of bacteria, making it a candidate for the development of new therapeutics. In terms of pathogenicity, while Micromonospora craterilacus is not typically associated with human disease, its relatives have been implicated in opportunistic infections, particularly in immunocompromised individuals. This highlights the importance of understanding the ecological role of such microorganisms in human health and disease. Furthermore, the organism's ability to produce secondary metabolites may have implications for probiotic applications, as some Micromonospora species have shown beneficial effects on gut health. However, more research is needed to fully elucidate the specific mechanisms of action and potential health benefits of Micromonospora craterilacus. Overall, while Micromonospora craterilacus is not directly linked to any known outbreaks or severe infections, its role in antimicrobial resistance and potential therapeutic applications make it a significant organism for further study in the context of human health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Micromonospora craterilacus is a species of actinobacteria that is primarily associated with alkaline lake environments and sedimentary soils. This microorganism thrives in conditions characterized by high pH levels, often found in regions where mineral-rich waters contribute to the alkalinity of the habitat. The ecological niche of Micromonospora craterilacus is significant due to its ability to adapt to extreme conditions, which allows it to play a crucial role in nutrient cycling within these unique biomes. In these alkaline lakes, Micromonospora craterilacus contributes to the breakdown of organic matter, facilitating the release of nutrients that are essential for other organisms in the ecosystem. Its metabolic processes can influence the chemical composition of the water, impacting the overall health of the aquatic environment. Furthermore, this microorganism often engages in symbiotic relationships with other microbial communities, enhancing the biodiversity and stability of the ecosystem. Additionally, Micromonospora craterilacus is known for its potential in bioremediation, as it can degrade various pollutants found in its habitat. This ability not only aids in maintaining the ecological balance but also highlights the importance of this microorganism in environmental management practices. Overall, the presence of Micromonospora craterilacus in alkaline lake environments underscores its role as a vital component of the microbial community, contributing to both ecological function and environmental health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Micromonospora craterilacus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly valuable in the fermentation process, where it can be employed to synthesize secondary metabolites that have pharmaceutical relevance. In the realm of waste management, Micromonospora craterilacus has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This makes it a candidate for use in bioremediation efforts, where it can help in the detoxification of contaminated environments, such as soil and water, by degrading pollutants. Furthermore, the organism's enzymatic activity is of interest in biofuel production. It can be involved in the conversion of biomass into fermentable sugars, which can then be transformed into biofuels. This process is crucial for developing sustainable energy sources and reducing reliance on fossil fuels. Overall, Micromonospora craterilacus presents a multifaceted potential in pharmaceutical development, waste treatment, and renewable energy, making it a valuable microorganism in various industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	anthropic/claude-3-haiku:beta	google/gemini-pro	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemma-7b-it	google/gemma-7b-it	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	false	false	false	false	true	true	true	true	false	false	true	true	false	false	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	true	false	true	true	false	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true	false	false	true	true	false	false
Host association	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus

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