Mycobacterium cookii

General Information

Mycobacterium cookii is a fascinating microorganism within the genus Mycobacterium. This species is particularly interesting due to its unique metabolic capabilities and its potential applications in biotechnology and environmental science. One of the most notable characteristics of M. cookii is its ability to degrade complex hydrocarbons, making it a valuable candidate for bioremediation efforts, especially in environments contaminated with petroleum products. Additionally, Mycobacterium cookii has been studied for its role in the natural environment, where it contributes to the breakdown of organic matter. This species is also of interest due to its relatively slow growth rate compared to other bacteria, which can be a challenge in laboratory settings but also provides insights into the diverse life strategies of mycobacteria. From a research perspective, M. cookii offers a window into the broader ecological roles of mycobacteria and their interactions with other microorganisms and the environment. Its ability to survive in harsh conditions and its metabolic versatility make it a subject of ongoing scientific investigation, particularly in the fields of environmental microbiology and industrial applications. Overall, Mycobacterium cookii stands out due to its biodegradation potential, ecological significance, and the insights it provides into mycobacterial diversity and adaptation.

Mycobacterium cookii is a species of the genus Mycobacterium that has garnered interest due to its unique ecological niche and potential applications in biotechnology. This organism is notable for its ability to thrive in extreme environments, particularly in soil and water contaminated with hydrocarbons, which makes it a candidate for bioremediation efforts. Its capacity to degrade complex organic compounds is particularly valuable in the context of environmental cleanup, as it can help in the breakdown of pollutants such as petroleum products. Another interesting aspect of M. cookii is its genetic diversity, which can provide insights into the evolutionary adaptations of mycobacteria to various environmental stresses. Researchers are particularly keen on studying its metabolic pathways, which may reveal novel enzymes that could be harnessed for industrial applications. Furthermore, M. cookii has been studied for its potential role in the microbiome of certain ecosystems, contributing to nutrient cycling and soil health. Its interactions with other microorganisms can shed light on the complex relationships within microbial communities. Overall, Mycobacterium cookii represents a fascinating subject for research, with implications for environmental science, biotechnology, and microbial ecology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycobacterium

Species: Mycobacterium cookii

NCBI ID

1775

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/010/727/945/GCA_010727945.1_ASM1072794v1

File for sequence-based predictions:
GCA_010727945.1_ASM1072794v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycobacterium cookii is a member of the Mycobacterium genus, which is known for its clinical significance primarily in relation to infections and disease associations. While M. cookii is less studied compared to other mycobacteria, it has been isolated from clinical specimens, indicating its potential role in human health and disease. Pathogenicity is a key concern, as some mycobacteria are known to cause serious diseases such as tuberculosis and leprosy. Although M. cookii has not been definitively linked to specific outbreaks, its presence in clinical settings suggests it may contribute to opportunistic infections, particularly in immunocompromised individuals. In terms of antimicrobial resistance, mycobacteria are notorious for their ability to develop resistance to multiple drugs, complicating treatment options. This resistance can be attributed to various mechanisms, including the formation of biofilms and the presence of efflux pumps that expel antibiotics from the bacterial cell. Understanding the resistance patterns of M. cookii is crucial for effective management of infections it may cause. Furthermore, the interaction of M. cookii with the human immune system is an area of interest, particularly regarding its immune evasion strategies. Mycobacteria can manipulate host immune responses, allowing them to survive within macrophages and evade detection by the immune system. This ability to persist in the host can lead to chronic infections, which are difficult to treat. While there are no specific medical applications currently documented for M. cookii, the broader implications of mycobacterial research may inform future developments in therapeutics and vaccines targeting mycobacterial diseases. Overall, the clinical relevance of Mycobacterium cookii underscores the importance of continued research into its pathogenic potential and interactions with human health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycobacterium cookii has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to degrade complex organic compounds, making it a candidate for biodegradation processes in contaminated environments. Its enzymatic activity can facilitate the breakdown of pollutants, thus contributing to effective waste treatment solutions. In the realm of biofuel production, Mycobacterium cookii may play a role in the conversion of biomass into biofuels through fermentation processes. By utilizing its metabolic pathways, this microorganism can potentially enhance the efficiency of biofuel generation from organic waste materials. Furthermore, there is interest in the pharmaceutical development sector, where Mycobacterium cookii could be explored for its unique metabolic products. These metabolites may have therapeutic properties, leading to the discovery of new drugs or treatments. Overall, the versatility of Mycobacterium cookii in biodegradation, fermentation, and potential pharmaceutical applications highlights its significance in advancing sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemma-7b-it	perplexity/llama-3-sonar-small-32k-chat	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	true	true	true	false	true	true	true	false	false	false	false	true	false	false	false	false	true	true	true	true	true	true	false	false	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	TRUE	true ✓	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	false	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗

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