Mycolicibacterium flavescens

General Information

Mycolicibacterium flavescens is a fascinating microorganism belonging to the genus Mycolicibacterium. This genus is known for its complex cell wall structure, which includes mycolic acids, contributing to its resilience and unique staining properties. One of the most intriguing aspects of M. flavescens is its potential role in bioremediation. This species has shown promise in degrading environmental pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, M. flavescens has been studied for its interactions with other microorganisms and its ability to survive in diverse environments, from soil to water systems. Its adaptability and metabolic versatility make it a subject of interest for researchers exploring microbial ecology and environmental microbiology. Furthermore, the study of M. flavescens can provide insights into the broader characteristics of the Mycolicibacterium genus, which includes several species of medical and industrial importance. Overall, Mycolicibacterium flavescens stands out due to its environmental applications and its role in advancing our understanding of microbial diversity and function.

Mycolicibacterium flavescens is a fascinating species within the genus Mycolicibacterium, which is known for its unique lipid composition and ecological versatility. This organism is particularly interesting due to its ability to produce mycolic acids, which are long-chain fatty acids that contribute to the robustness of its cell wall. This characteristic not only provides structural integrity but also plays a significant role in the organism's resistance to environmental stressors, making it a subject of interest in studies related to microbial survival in harsh conditions. One of the unique aspects of M. flavescens is its potential biotechnological applications. The mycolic acids produced by this species can be utilized in the development of novel antimicrobial agents, as they exhibit properties that can inhibit the growth of various pathogens. This makes M. flavescens a valuable organism in the search for new antibiotics, especially in an era where antibiotic resistance is a growing concern. Additionally, M. flavescens has been isolated from diverse environments, including soil and water, indicating its ecological adaptability. This adaptability allows researchers to explore its role in biogeochemical cycles and its interactions with other microorganisms in various ecosystems. The organism's ability to thrive in different habitats makes it a model for studying microbial ecology and evolution. Furthermore, the genomic and metabolic pathways of M. flavescens are of significant interest, as they may provide insights into the mechanisms of lipid biosynthesis and the evolutionary adaptations of mycolic acid-producing bacteria. Understanding these pathways can enhance our knowledge of microbial physiology and lead to advancements in synthetic biology. In summary, Mycolicibacterium flavescens stands out due to its unique lipid composition, potential for biotechnological applications, ecological versatility, and the insights it offers into microbial metabolism and evolution. Its study could pave the way for innovative solutions in medicine and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium flavescens

NCBI ID

1776

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/001/722/335/GCF_001722335.1_ASM172233v1

File for sequence-based predictions:
GCF_001722335.1_ASM172233v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium flavescens is a member of the genus Mycolicibacterium, which is known for its complex lipid composition and unique cell wall structure. This microorganism has been associated with various clinical implications, particularly in the context of infections and its role in human health. Clinical relevance includes its potential to cause opportunistic infections, especially in immunocompromised individuals. It has been isolated from clinical specimens, indicating its pathogenic potential, although it is not as widely recognized as other mycobacterial species such as Mycobacterium tuberculosis. One of the significant concerns regarding Mycolicibacterium flavescens is its antimicrobial resistance. Like many mycobacteria, it may exhibit resistance to common antibiotics, complicating treatment options for infections. This resistance is often attributed to its unique cell wall structure, which can impede the penetration of antimicrobial agents. In terms of immune evasion, Mycolicibacterium flavescens may employ strategies similar to other mycobacteria, such as modulating the host's immune response to avoid detection and destruction by immune cells. This ability to evade the immune system can lead to chronic infections, particularly in patients with weakened immune systems. While there is limited information on specific outbreaks associated with Mycolicibacterium flavescens, its presence in clinical settings raises concerns about its role in nosocomial infections. Further research is needed to fully understand its pathogenic mechanisms and potential as a target for therapeutic interventions. Overall, Mycolicibacterium flavescens represents a noteworthy organism in the context of emerging mycobacterial pathogens, warranting attention for its clinical implications and the need for effective management strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium flavescens is a species of actinobacteria that is primarily associated with various terrestrial environments and soil ecosystems. This microorganism thrives in nutrient-rich soils and is often found in areas with high organic matter content, such as decaying plant material and compost. Its ability to degrade complex organic compounds makes it an important player in the nutrient cycling process within these habitats. In addition to its role in decomposition, Mycolicibacterium flavescens is known for its symbiotic relationships with plants. It can enhance soil fertility by promoting the availability of essential nutrients, thereby supporting plant growth. This interaction is particularly significant in agricultural ecosystems, where it can contribute to sustainable farming practices by improving soil health. Furthermore, Mycolicibacterium flavescens exhibits remarkable environmental adaptability, allowing it to survive in a range of conditions, including varying pH levels and moisture content. This adaptability enables it to colonize diverse habitats, from arid soils to wetlands, making it a versatile organism within its ecological niche. Overall, Mycolicibacterium flavescens plays a crucial role in maintaining the health of soil ecosystems, contributing to biodiversity and the overall functioning of terrestrial biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium flavescens has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Mycolicibacterium flavescens is utilized for its ability to produce specific enzymes that can be harnessed in biocatalysis processes. These enzymes can facilitate chemical reactions in a more environmentally friendly manner compared to traditional chemical methods. In the realm of waste management, Mycolicibacterium flavescens has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic compounds. This property is particularly valuable in the treatment of contaminated environments, where the microorganism can help in the remediation of pollutants, thus contributing to cleaner ecosystems. Furthermore, the organism has been explored for its role in biofuel production. Through fermentation processes, Mycolicibacterium flavescens can convert biomass into biofuels, providing a sustainable alternative to fossil fuels. This application is crucial in the ongoing search for renewable energy sources. In pharmaceutical development, the unique metabolic pathways of Mycolicibacterium flavescens are being studied for the production of bioactive compounds that may have therapeutic effects. The potential for these compounds to serve as new drugs or as precursors in drug synthesis is an exciting area of research. Overall, Mycolicibacterium flavescens represents a versatile microorganism with promising applications across multiple industries, particularly in enzyme production, biodegradation, and fermentation processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemma-7b-it	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemini-pro	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	false	false	false	true	false	true	false	true	false	true	true	false	false	false	false	false	false	true	true	false	false	false	false
Biofilm formation	N/A	true	true	true	true	true	false	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	true	true	true	true	false	true	true	true	false	false	false	false	true	true	true	true	true	true	false	false
Host association	TRUE	false ✗	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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