Acinetobacter proteolyticus

General Information

Acinetobacter proteolyticus is a fascinating microorganism that belongs to the genus Acinetobacter, which is known for its remarkable adaptability and resilience in various environments. One of the most intriguing aspects of A. proteolyticus is its proteolytic activity, which means it has the ability to break down proteins into smaller peptides or amino acids. This characteristic makes it particularly interesting for research in the fields of biotechnology and industrial applications, where proteases are valuable for processes such as waste treatment, leather processing, and the production of detergents. Another notable feature of A. proteolyticus is its environmental versatility. It can be found in diverse habitats, ranging from soil and water to hospital settings, where it can survive under various conditions. This adaptability is partly due to its robust metabolic capabilities, allowing it to utilize a wide range of organic compounds as sources of carbon and energy. From a clinical perspective, A. proteolyticus is of interest due to its potential role in nosocomial infections. While not as notorious as some other Acinetobacter species, it still poses a risk in healthcare environments, particularly for immunocompromised patients. Understanding its mechanisms of pathogenicity and resistance can provide insights into better management and treatment strategies for infections caused by this organism. In summary, Acinetobacter proteolyticus stands out due to its proteolytic capabilities, environmental adaptability, and clinical significance. These characteristics make it a valuable subject for ongoing research in microbiology, biotechnology, and medical science.

Acinetobacter proteolyticus is a fascinating bacterium known for its proteolytic capabilities, which allow it to break down proteins into smaller peptides and amino acids. This characteristic makes it particularly interesting in the context of biotechnology and environmental microbiology. The ability to degrade complex organic materials positions A. proteolyticus as a potential candidate for applications in waste treatment and bioremediation, where it could help in the breakdown of pollutants and organic waste in various environments. One of the unique aspects of A. proteolyticus is its adaptability to diverse environments, including soil and water, which suggests a robust metabolic versatility. This adaptability is crucial for survival in fluctuating conditions, making it a valuable organism for studying microbial ecology and the dynamics of microbial communities. Furthermore, research into A. proteolyticus can provide insights into protein metabolism and the mechanisms of proteolysis, which are essential for understanding nutrient cycling in ecosystems. The study of its proteolytic enzymes may also have implications for industrial processes, such as the development of new enzymes for use in food processing or pharmaceuticals. Overall, Acinetobacter proteolyticus stands out not only for its biochemical capabilities but also for its potential applications in environmental sustainability and industrial biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter proteolyticus

NCBI ID

1776741

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/029/168/555/GCF_029168555.1_ASM2916855v1

File for sequence-based predictions:
GCF_029168555.1_ASM2916855v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Acinetobacter proteolyticus is a member of the Acinetobacter genus, which is known for its clinical significance, particularly in hospital settings. This organism has been associated with various infections, including pneumonia, wound infections, and bacteremia. Its role in human health is complex, as it can be both a commensal organism and a potential pathogen, especially in immunocompromised patients. One of the critical aspects of Acinetobacter proteolyticus is its pathogenicity. It possesses several virulence factors that enable it to adhere to host tissues and evade the immune response. This includes the production of biofilms, which can protect the bacteria from phagocytosis and antibiotic treatment. In terms of antimicrobial resistance, Acinetobacter proteolyticus is part of a broader group of Acinetobacter species that are notorious for their ability to develop resistance to multiple classes of antibiotics, including beta-lactams, aminoglycosides, and fluoroquinolones. This resistance poses significant challenges in clinical management, leading to increased morbidity and mortality rates associated with infections caused by this organism. While Acinetobacter proteolyticus is not commonly highlighted in the context of outbreaks, its presence in healthcare-associated infections underscores the importance of infection control measures. Understanding its mechanisms of resistance and pathogenicity is crucial for developing effective treatment strategies and improving patient outcomes. Overall, the clinical implications of Acinetobacter proteolyticus are significant, particularly in the context of nosocomial infections and the ongoing challenge of antimicrobial resistance.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter proteolyticus is a bacterium commonly found in various habitat types that are rich in organic matter. This microorganism thrives in environments such as soil, freshwater, and marine ecosystems, where it plays a significant role in the decomposition of organic materials. Its ability to degrade proteins makes it an important player in nutrient cycling, particularly in the breakdown of complex organic compounds into simpler forms that can be utilized by other organisms. In soil ecosystems, A. proteolyticus contributes to the microbial community by participating in the degradation of organic matter, thus enhancing soil fertility and structure. It often exists in symbiotic relationships with plants, aiding in nutrient availability, which can promote plant growth and health. In freshwater environments, this bacterium can be found in sediments and water columns, where it interacts with other microbial communities. Its presence can indicate the health of the ecosystem, as it is involved in the breakdown of pollutants and organic waste, thereby contributing to bioremediation efforts. In marine habitats, A. proteolyticus has been isolated from various sources, including sediments and seawater, where it plays a role in the degradation of organic materials, thus influencing the marine nutrient cycle. Its adaptability to different salinities and temperatures allows it to thrive in diverse marine environments, showcasing its ecological versatility. Overall, Acinetobacter proteolyticus is a vital microorganism in various biomes, contributing to nutrient cycling, decomposition processes, and ecosystem health.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter proteolyticus has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Acinetobacter proteolyticus is utilized for its ability to produce enzymes that can break down complex proteins. This enzymatic activity is particularly valuable in the food industry for fermentation processes, where it can enhance the flavor and texture of fermented products. In the realm of waste management, Acinetobacter proteolyticus has been documented for its role in biodegradation of organic pollutants. This capability allows it to be employed in the treatment of wastewater, where it helps in the breakdown of harmful substances, thus contributing to environmental sustainability. Furthermore, the organism has potential applications in biofuel production. Its metabolic pathways can be harnessed to convert organic waste into biofuels through fermentation, making it a candidate for sustainable energy solutions. In pharmaceutical development, Acinetobacter proteolyticus is being explored for its ability to produce bioactive compounds that may have therapeutic properties. This includes the potential for developing new antibiotics or other medicinal compounds, leveraging its unique metabolic capabilities. Overall, Acinetobacter proteolyticus demonstrates versatility across multiple industries, particularly in enzyme production, biodegradation, and fermentation, making it a valuable microorganism for future industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	anthropic/claude-3-haiku:beta	google/gemma-7b-it	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemini-pro	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4o	openai/gpt-4o
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain negative	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true	false	false	true	true	true	true	false	false	false	false	true	true
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true	false	false	true	true	true	true
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	gamma ✓	gamma ✓	gamma ✓	alpha ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

Back to Search