Mycolicibacterium komossense

General Information

Mycolicibacterium komossense is a fascinating microorganism belonging to the genus Mycolicibacterium. This genus is known for its complex and unique cell wall structure, which includes mycolic acids, contributing to its resilience and distinctive characteristics. One of the most intriguing aspects of M. komossense is its potential application in bioremediation. This organism has shown the ability to degrade various environmental pollutants, including aromatic hydrocarbons, making it a valuable candidate for cleaning up contaminated sites. Additionally, M. komossense is of interest due to its phylogenetic placement within the Mycobacteriaceae family, which includes notable pathogens like Mycobacterium tuberculosis. However, unlike its pathogenic relatives, M. komossense is generally considered non-pathogenic, which opens up possibilities for its use in industrial and environmental applications without significant health risks. Another key feature of M. komossense is its slow growth rate, which is characteristic of many mycobacteria. This slow growth can be a challenge for laboratory studies but also provides insights into the metabolic and physiological adaptations of slow-growing bacteria. Researchers are particularly interested in understanding the genetic and biochemical pathways that enable M. komossense to survive and thrive in diverse and often harsh environments. In summary, Mycolicibacterium komossense stands out due to its potential in bioremediation, its non-pathogenic nature, and its slow growth rate, making it a valuable subject for research in environmental microbiology and microbial ecology.

Mycolicibacterium komossense is a fascinating species within the genus Mycolicibacterium, which is known for its unique lipid composition and ecological versatility. This organism is particularly interesting due to its ability to produce mycolic acids, which are long-chain fatty acids that play a crucial role in the structural integrity of the cell wall. These mycolic acids contribute to the organism's resistance to environmental stressors, making it a subject of interest in studies related to microbial survival in harsh conditions. One of the unique aspects of M. komossense is its potential for biotechnological applications. The organism has been explored for its ability to degrade complex organic compounds, which could be valuable in bioremediation efforts. This capability positions M. komossense as a potential candidate for use in the treatment of contaminated environments, particularly in the breakdown of pollutants that are resistant to conventional degradation processes. Additionally, M. komossense has been isolated from various environmental sources, indicating its adaptability and ecological significance. Its presence in diverse habitats suggests that it may play a role in nutrient cycling and ecosystem functioning. The study of this microorganism can provide insights into microbial interactions within its environment and contribute to our understanding of microbial ecology. Overall, the unique characteristics of Mycolicibacterium komossense, particularly its lipid composition and potential biotechnological applications, make it a valuable organism for research in microbiology, ecology, and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium komossense

NCBI ID

1779

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/025/822/605/GCF_025822605.1_ASM2582260v1

File for sequence-based predictions:
GCF_025822605.1_ASM2582260v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium komossense is a member of the genus Mycolicibacterium, which is known for its complex lipid composition and potential pathogenicity. While specific clinical implications of M. komossense are not as extensively documented as those of other mycobacteria, it is important to consider its role in human health and disease. This organism has been associated with infections in immunocompromised individuals, particularly in cases where it may act as an opportunistic pathogen. Clinical relevance arises from its potential to cause pulmonary infections and cutaneous lesions, especially in patients with underlying health conditions or weakened immune systems. Furthermore, M. komossense may exhibit antimicrobial resistance, which complicates treatment options. The presence of mycolic acids in its cell wall contributes to its resistance against common antibiotics, making it a concern in clinical settings. Understanding its mechanisms of immune evasion is crucial, as it may employ strategies similar to other mycobacteria, such as inhibiting phagosome-lysosome fusion and modulating host immune responses. While research on M. komossense is still emerging, its identification in clinical samples underscores the need for awareness regarding its potential pathogenicity and the importance of accurate diagnostic methods. Continued investigation into its role in human disease, including any possible outbreaks or associations with specific infections, will be essential for developing effective treatment and prevention strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium komossense is a species of bacterium that is primarily associated with soil environments and marine ecosystems. This microorganism thrives in nutrient-rich substrates, often found in areas with high organic matter content. Its ecological niche is characterized by the ability to degrade complex organic compounds, playing a crucial role in the nutrient cycling process within these biomes. In soil habitats, M. komossense contributes to the breakdown of organic materials, facilitating the release of nutrients back into the ecosystem. This process is vital for maintaining soil health and fertility, supporting plant growth and the overall productivity of terrestrial ecosystems. The bacterium's ability to adapt to varying soil conditions, including moisture levels and pH, allows it to occupy diverse soil types, from sandy soils to clay-rich environments. In marine environments, M. komossense has been identified in sediments and biofilms, where it interacts with other microorganisms. Its presence is significant in the degradation of organic matter in coastal areas, contributing to the detrital food web and influencing the dynamics of microbial communities. The bacterium may also engage in symbiotic relationships with other marine organisms, enhancing nutrient availability and promoting biodiversity. Overall, Mycolicibacterium komossense plays a critical role in both terrestrial and aquatic biomes, facilitating nutrient cycling and supporting the health of ecosystems through its metabolic activities.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium komossense has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in biodegradation processes, which can be harnessed for the breakdown of complex organic materials in waste treatment facilities. Its enzymatic activity allows it to effectively degrade pollutants, making it a candidate for bioremediation efforts aimed at cleaning contaminated environments. In the realm of biofuel production, Mycolicibacterium komossense can be involved in fermentation processes that convert biomass into biofuels. The organism's metabolic pathways may facilitate the conversion of lignocellulosic materials into fermentable sugars, which can then be transformed into ethanol or other biofuels, contributing to sustainable energy solutions. Additionally, the unique biochemical properties of Mycolicibacterium komossense may lead to advancements in pharmaceutical development. Its metabolites could be explored for their potential therapeutic effects, particularly in the development of new antibiotics or other bioactive compounds. The organism's ability to produce specific enzymes can also be leveraged in the production of pharmaceuticals, enhancing the efficiency of drug synthesis. Overall, Mycolicibacterium komossense presents a promising avenue for innovation across multiple industries, particularly through its roles in biodegradation, fermentation, and enzyme production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	google/gemma-7b-it	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain variable ✗	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	false	true	true	false	true	false	false	false	false	false	false	false	true	true	false	false	false	false	true	true	false	false	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	N/A	true	true	true	false	false	false	false	false	false	false	false	false	false	true	true	false	false	true	true	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	false	false	true	true	false	false	false	false	false	true	true	false	false	true	true	false	false	true	true	false	false	true	true
Host association	TRUE	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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