Mycolicibacterium fallax

General Information

Source: gpt-4o-2024-05-13

Mycolicibacterium fallax is a fascinating microorganism belonging to the genus Mycolicibacterium, which is known for its complex and unique cell wall structure rich in mycolic acids. One of the most intriguing aspects of M. fallax is its potential role in biodegradation and bioremediation. This species has been studied for its ability to degrade various environmental pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, M. fallax exhibits a remarkable resistance to desiccation and other environmental stresses, which is attributed to its robust cell wall. This resilience makes it an interesting subject for research into microbial survival mechanisms under extreme conditions. From a clinical perspective, while M. fallax is not typically associated with human disease, its close relatives within the Mycolicibacterium genus include pathogens of significant medical importance. This relationship provides a comparative framework for understanding pathogenicity and developing new therapeutic strategies. In summary, Mycolicibacterium fallax stands out due to its environmental resilience, potential applications in bioremediation, and its relevance to broader microbiological and medical research.**

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium fallax

NCBI ID

1793

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/010/726/955/GCA_010726955.1_ASM1072695v1

File for sequence-based predictions:
GCA_010726955.1_ASM1072695v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium fallax is a member of the genus Mycolicibacterium, which has been associated with various clinical implications, particularly in the context of infections and pathogenicity. This microorganism is known to be a potential opportunistic pathogen, especially in immunocompromised individuals. It has been linked to pulmonary infections and can cause cutaneous infections in patients with underlying health conditions. The clinical relevance of Mycolicibacterium fallax is underscored by its ability to evade the immune response, which may involve mechanisms such as altering its surface antigens and producing biofilms that protect it from host defenses and antimicrobial agents. In terms of antimicrobial resistance, Mycolicibacterium fallax has shown resistance to several common antibiotics, which complicates treatment options for infections caused by this organism. This resistance is particularly concerning in the context of treatment failures and the need for alternative therapeutic strategies. While research on Mycolicibacterium fallax is still emerging, its role in outbreaks and its potential as a pathogen in specific populations highlight the need for increased awareness and further studies to understand its clinical implications fully. Overall, the organism's interactions with the human body and its pathogenic potential warrant attention in clinical microbiology and infectious disease management.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium fallax is a species of bacteria that is primarily associated with soil environments and decaying organic matter. This microorganism thrives in nutrient-rich substrates, where it plays a crucial role in the decomposition process. Its presence is often linked to the breakdown of complex organic compounds, contributing to nutrient cycling within the ecosystem. In particular, Mycolicibacterium fallax is known to inhabit temperate forests and grasslands, where it can be found in the rhizosphere of plants. Here, it engages in symbiotic relationships with plant roots, aiding in nutrient uptake and enhancing soil health. This interaction not only benefits the plants but also promotes a diverse microbial community in the soil. Additionally, Mycolicibacterium fallax has been observed in wetlands, where it contributes to the degradation of organic materials in anaerobic conditions. Its ability to adapt to varying moisture levels and nutrient availability makes it a resilient organism in these dynamic environments. Overall, Mycolicibacterium fallax plays a significant role in maintaining the health of its associated biomes, facilitating nutrient cycling, supporting plant growth, and contributing to the overall biodiversity of the ecosystem.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium fallax has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in biodegradation processes, which can be harnessed for the breakdown of complex organic materials in waste treatment facilities. Its enzymatic activity allows it to effectively degrade pollutants, making it a candidate for bioremediation efforts aimed at cleaning contaminated environments. In the realm of biofuel production, Mycolicibacterium fallax can be involved in fermentation processes that convert biomass into biofuels. The organism's metabolic pathways may facilitate the conversion of lignocellulosic materials into fermentable sugars, which can then be transformed into ethanol or other biofuels, contributing to sustainable energy solutions. Additionally, the unique biochemical properties of Mycolicibacterium fallax may be explored in pharmaceutical development. Its ability to produce specific metabolites could lead to the discovery of novel compounds with therapeutic potential. Research into its secondary metabolites may yield new antibiotics or other bioactive substances that can be utilized in medicine. Overall, Mycolicibacterium fallax presents a promising avenue for innovation across multiple industries, particularly through its roles in biodegradation, fermentation, and the production of valuable biochemical compounds.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	google/gemma-7b-it	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	anthropic/claude-3-haiku:beta	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain variable ✗	gram stain negative ✗	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	true	true	true	false	true	true	false	false	false	false	false	false	false	false	true	true	true	true	false	false	false	false	false	false
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	false	false
Animal pathogenicity	TRUE	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	false ✗	true ✓	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	false	false	true	true	false	false
Host association	TRUE	true ✓	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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