Mycolicibacter virginiensis

General Information

Mycolicibacter virginiensis is a fascinating microorganism belonging to the genus Mycolicibacter. This genus is known for its members' complex cell wall structures, which include mycolic acids, contributing to their resilience and unique staining properties. One of the most intriguing aspects of M. virginiensis is its potential role in bioremediation. This organism has shown promise in breaking down environmental pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, M. virginiensis is of interest due to its phylogenetic placement within the Mycobacteriaceae family, which includes notable pathogens like Mycobacterium tuberculosis. However, unlike its pathogenic relatives, M. virginiensis is not typically associated with disease, making it a safer model for studying the biology and genetics of mycolic acid-containing bacteria. Another key characteristic of M. virginiensis is its ability to produce secondary metabolites with potential pharmaceutical applications. These compounds can have antimicrobial, antifungal, or anticancer properties, highlighting the organism's potential in drug discovery and development. In summary, Mycolicibacter virginiensis stands out due to its environmental applications, non-pathogenic nature, and potential in pharmaceutical research, making it a valuable subject for scientific study.

Mycolicibacter virginiensis is a species of actinobacteria that has garnered interest due to its unique biochemical properties and ecological significance. This microorganism is notable for its ability to produce mycolic acids, which are long-chain fatty acids that contribute to the complex cell wall structure typical of the genus Mycolicibacter. These mycolic acids play a crucial role in the organism's resistance to environmental stresses, making it a fascinating subject for studies on microbial survival mechanisms. One of the most intriguing aspects of Mycolicibacter virginiensis is its potential in biotechnological applications. The organism has been explored for its ability to degrade various environmental pollutants, including hydrocarbons, which positions it as a candidate for bioremediation efforts. This capability not only highlights its ecological importance but also opens avenues for research into sustainable environmental management practices. Furthermore, Mycolicibacter virginiensis has been studied for its antimicrobial properties, which may lead to the discovery of novel compounds with therapeutic potential. The exploration of its secondary metabolites could yield new insights into drug development, particularly in the context of antibiotic resistance, a growing concern in modern medicine. In summary, Mycolicibacter virginiensis stands out due to its unique biochemical characteristics, ecological roles, and potential applications in biotechnology and medicine, making it a valuable organism for ongoing research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacter

Species: Mycolicibacter virginiensis

NCBI ID

1795032

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/022/374/935/GCA_022374935.2_ASM2237493v2

File for sequence-based predictions:
GCA_022374935.2_ASM2237493v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacter virginiensis is a member of the genus Mycolicibacter, which is known for its association with various clinical implications. This microorganism has been implicated in infections primarily in immunocompromised individuals, particularly those with underlying conditions such as HIV/AIDS or diabetes. It is recognized for its potential to cause pulmonary infections, which can mimic those caused by more common pathogens like Mycobacterium tuberculosis. One of the significant concerns regarding Mycolicibacter virginiensis is its antimicrobial resistance. Strains of this organism have shown resistance to multiple classes of antibiotics, complicating treatment options and leading to prolonged infections that can be difficult to manage. This resistance is often attributed to the organism's ability to form biofilms and its inherent mechanisms for evading the host's immune response. In terms of its role in human health, while Mycolicibacter virginiensis is not typically considered a part of the normal human microbiota, its presence in clinical specimens raises concerns about its pathogenic potential. The organism has been associated with rare cases of cutaneous infections and has been isolated from various clinical samples, indicating its opportunistic nature. Currently, there are no widely recognized medical applications such as probiotics or vaccines specifically targeting Mycolicibacter virginiensis. However, understanding its pathogenic mechanisms and resistance profiles is crucial for developing effective therapeutic strategies. Continued surveillance and research are necessary to better understand the clinical significance of this organism and its impact on public health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacter virginiensis is a species of actinobacteria that is primarily associated with soil and aquatic environments. This microorganism thrives in a variety of ecological niches, particularly in areas rich in organic matter and nutrients. It is commonly found in freshwater ecosystems, where it plays a significant role in the decomposition of organic materials, contributing to nutrient cycling within the habitat. In addition to its presence in soil, Mycolicibacter virginiensis has been documented in marine environments, where it can be isolated from sediments and biofilms. Its ability to adapt to different salinities and nutrient availabilities allows it to occupy diverse habitats, making it a versatile organism in various ecosystems. Notably, Mycolicibacter virginiensis is involved in symbiotic relationships with plants and other microorganisms. It can enhance soil fertility and plant growth by facilitating nutrient uptake, particularly in nutrient-poor soils. This interaction underscores its importance in maintaining the health of terrestrial ecosystems. Furthermore, this microorganism exhibits environmental adaptability, allowing it to survive in fluctuating conditions, such as changes in temperature and moisture levels. Its resilience contributes to its role in bioremediation, where it can help degrade pollutants in contaminated environments, thus playing a crucial part in ecosystem restoration efforts. Overall, Mycolicibacter virginiensis is a key player in both terrestrial and aquatic biomes, contributing to ecological balance and sustainability through its various interactions and roles within these environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacter virginiensis has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Mycolicibacter virginiensis is utilized for its ability to produce unique lipids and mycolic acids, which can be harnessed for the development of novel biomaterials and pharmaceuticals. These compounds are particularly valuable in the formulation of drug delivery systems and as potential anti-tuberculosis agents due to their antimicrobial properties. In the realm of waste management, Mycolicibacter virginiensis has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic pollutants. This makes it a candidate for bioremediation processes aimed at cleaning up contaminated environments, such as oil spills or heavy metal-laden sites, where its metabolic pathways can be exploited to detoxify harmful substances. Furthermore, the organism has been investigated for its role in biofuel production. Through fermentation processes, Mycolicibacter virginiensis can convert organic materials into biofuels, contributing to sustainable energy solutions. Its metabolic versatility allows it to utilize various substrates, enhancing the efficiency of biofuel generation. In pharmaceutical development, the unique biochemical pathways of Mycolicibacter virginiensis are being explored for the production of novel antibiotics and other therapeutic agents. The organism's ability to synthesize complex molecules can lead to the discovery of new drugs that target resistant strains of bacteria. Overall, Mycolicibacter virginiensis represents a promising candidate for multiple industries, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its versatility and importance in modern industrial applications.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3-haiku:beta	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemma-7b-it	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	false	false	false	true	true	true	false	false	false	false	false	false	true	true	true	true	false	false	false	false	false	false	false	false
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	TRUE	false ✗	true ✓	true ✓	false ✗	true ✓	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	true	false	true	true	true	false	false	true	true	true	true	false	false	false	false	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	false	true	false	true	true	true	false	false	false	false	true	true	false	false	false	false	true	true	true	true	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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