Mycolicibacterium senegalense

General Information

Mycolicibacterium senegalense is a fascinating microorganism belonging to the genus Mycolicibacterium. This genus is known for its complex cell wall structure, which includes mycolic acids, contributing to its resilience and unique properties. One of the most intriguing aspects of M. senegalense is its ability to degrade complex hydrocarbons, making it a valuable candidate for bioremediation efforts, particularly in environments contaminated with petroleum products. Additionally, M. senegalense has been studied for its potential in biotechnological applications due to its enzymatic capabilities. The organism produces a variety of enzymes that can break down organic materials, which could be harnessed for industrial processes such as waste treatment and the production of biofuels. From a medical perspective, M. senegalense is noteworthy because it is part of the non-tuberculous mycobacteria (NTM) group, which can cause infections in humans, particularly in immunocompromised individuals. Understanding its pathogenic mechanisms and resistance profiles is crucial for developing effective treatments. Overall, Mycolicibacterium senegalense stands out due to its environmental resilience, bioremediation potential, and biotechnological applications, making it a subject of significant interest in both environmental and medical microbiology research.

Mycolicibacterium senegalense is a fascinating species within the genus Mycolicibacterium, which is known for its unique lipid composition and ecological versatility. This organism is particularly interesting due to its ability to thrive in diverse environments, including soil and aquatic habitats, which highlights its adaptability and potential role in biogeochemical cycles. One of the most notable characteristics of M. senegalense is its production of mycolic acids, which are long-chain fatty acids that contribute to the organism's cell wall structure. These mycolic acids not only provide structural integrity but also play a crucial role in the organism's resistance to environmental stressors, making it a subject of interest in studies related to microbial survival and resilience. Furthermore, M. senegalense has been identified as a potential source of bioactive compounds. Research into its metabolic pathways may reveal novel substances with antimicrobial or antifungal properties, which could have significant implications for pharmaceutical development. The exploration of its secondary metabolites is an exciting avenue for discovering new drugs, especially in the context of rising antibiotic resistance. Additionally, the ecological role of M. senegalense in nutrient cycling and its interactions with other microorganisms in its environment make it a valuable organism for studies in microbial ecology. Understanding how this species interacts with its surroundings can provide insights into ecosystem dynamics and the importance of microbial communities in maintaining environmental health. In summary, Mycolicibacterium senegalense stands out due to its unique lipid composition, potential for producing bioactive compounds, and its ecological significance, making it a promising candidate for further research in microbiology and biotechnology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium senegalense

NCBI ID

1796

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/019/645/875/GCA_019645875.1_ASM1964587v1

File for sequence-based predictions:
GCA_019645875.1_ASM1964587v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium senegalense is a member of the genus Mycolicibacterium, which is known for its complex lipid composition and unique cell wall structure. This microorganism has been associated with various clinical implications, particularly in the context of infections and pathogenicity. It has been identified as a potential pathogen in immunocompromised individuals, leading to pulmonary infections and cutaneous lesions. The clinical relevance of M. senegalense is underscored by its ability to evade the immune response, which may involve mechanisms such as the modulation of host cell signaling pathways and the production of immunosuppressive factors. Furthermore, there is growing concern regarding antimicrobial resistance among mycobacterial species, including M. senegalense. Reports suggest that this organism may exhibit resistance to common antibiotics, complicating treatment options for affected patients. The presence of such resistance mechanisms highlights the need for ongoing surveillance and research to better understand the epidemiology and treatment of infections caused by this organism. In terms of medical applications, while M. senegalense is not widely recognized for therapeutic use, its relatives in the Mycobacterium genus have been explored for potential probiotic applications and as candidates for vaccines against other mycobacterial diseases. However, the specific role of M. senegalense in these areas remains to be fully elucidated. Overall, the clinical implications of Mycolicibacterium senegalense warrant further investigation to clarify its pathogenic potential and to develop effective management strategies for infections associated with this organism.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium senegalense is a species of bacteria that is primarily associated with soil environments and aquatic habitats. This microorganism thrives in tropical and subtropical regions, where it can be found in nutrient-rich soils and freshwater systems. Its ecological niche is often linked to the decomposition of organic matter, playing a crucial role in nutrient cycling within these ecosystems. In soil biomes, Mycolicibacterium senegalense contributes to the breakdown of complex organic compounds, aiding in the release of essential nutrients back into the soil. This process not only supports plant growth but also enhances soil health and fertility. The bacterium's ability to degrade various substrates makes it an important player in soil microbiomes, where it interacts with other microorganisms, forming complex networks that facilitate nutrient exchange and enhance soil structure. In aquatic environments, particularly in freshwater systems, Mycolicibacterium senegalense can be found in sediments and water columns, where it participates in the degradation of organic materials. Its presence in these habitats indicates a healthy ecosystem, as it helps maintain the balance of microbial communities and contributes to the overall productivity of the aquatic biome. Furthermore, this bacterium exhibits notable symbiotic relationships with plants and other microorganisms, enhancing their growth and resilience. Its adaptability to varying environmental conditions, such as changes in moisture and nutrient availability, underscores its ecological significance in both terrestrial and aquatic biomes. Overall, Mycolicibacterium senegalense plays a vital role in maintaining the health and functionality of the ecosystems it inhabits.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium senegalense has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in biodegradation processes, which can be harnessed for the breakdown of complex organic materials in waste treatment facilities. By utilizing the enzymatic activity of Mycolicibacterium senegalense, industries can improve the efficiency of waste treatment systems, leading to reduced environmental impact and enhanced resource recovery. In the realm of biofuel production, Mycolicibacterium senegalense may play a role in the fermentation of biomass, converting organic substrates into biofuels. This process not only contributes to sustainable energy solutions but also aids in the reduction of greenhouse gas emissions. Furthermore, the unique metabolic pathways of Mycolicibacterium senegalense can be explored for pharmaceutical development, particularly in the production of bioactive compounds. These compounds may have therapeutic properties, making the organism a candidate for further research in drug discovery and development. Overall, the applications of Mycolicibacterium senegalense in fermentation, biodegradation, and enzyme production highlight its significance in advancing industrial processes and promoting environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	anthropic/claude-3-haiku:beta	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemma-7b-it	google/gemma-7b-it	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	false	true	true	true	true	false	false	false	false	false	false	false	true	true	false	false	true	true	true	true	false	false	false	false
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗
Health association	N/A	true	true	true	true	false	true	true	false	true	false	false	false	false	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Host association	TRUE	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗

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