Mycolicibacterium aichiense

General Information

Mycolicibacterium aichiense is a fascinating microorganism belonging to the genus Mycolicibacterium, which is known for its complex and unique cell wall structure rich in mycolic acids. One of the most intriguing aspects of M. aichiense is its potential for bioremediation. This organism has shown the ability to degrade various environmental pollutants, including aromatic hydrocarbons, making it a valuable candidate for cleaning up contaminated sites. Another notable feature of Mycolicibacterium aichiense is its slow growth rate, which is characteristic of many mycobacteria. This slow growth can be a double-edged sword; while it poses challenges for laboratory cultivation and study, it also means that the organism can survive in harsh environmental conditions for extended periods. From a research perspective, M. aichiense is particularly interesting due to its genetic and metabolic pathways. Studies have shown that it possesses unique enzymes and metabolic capabilities that are not found in other bacteria, which could have applications in biotechnology and industrial microbiology. Additionally, the organism's resistance to certain antibiotics and its ability to form biofilms make it a subject of interest in medical microbiology, particularly in understanding how mycobacteria evade the immune system and persist in host organisms. In summary, Mycolicibacterium aichiense is a microorganism of significant interest due to its potential applications in bioremediation, its unique metabolic pathways, and its relevance to medical research. Its ability to degrade pollutants and survive in extreme conditions highlights its ecological importance and potential utility in various biotechnological applications.

Mycolicibacterium aichiense is a fascinating species within the genus Mycolicibacterium, which is known for its unique lipid composition and ecological versatility. This organism is particularly interesting due to its ability to produce mycolic acids, which are long-chain fatty acids that play a crucial role in the structural integrity of the cell wall. These mycolic acids contribute to the organism's resilience against environmental stresses, making it a subject of interest in studies related to microbial survival and adaptation. One of the notable aspects of M. aichiense is its potential biotechnological applications. The unique lipid profile of this species can be harnessed for the development of novel antimicrobial agents or as a model for studying lipid metabolism in bacteria. Researchers are particularly keen on exploring how the metabolic pathways of M. aichiense can be manipulated for industrial purposes, such as the production of biofuels or bioplastics. Additionally, M. aichiense has been isolated from various environmental sources, indicating its ecological significance. Its presence in diverse habitats suggests that it may play a role in nutrient cycling and the degradation of complex organic materials. This adaptability makes it a valuable organism for studying microbial ecology and the interactions within microbial communities. In summary, Mycolicibacterium aichiense stands out due to its unique biochemical properties, potential for biotechnological innovation, and ecological importance, making it a compelling subject for further research in microbiology and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium aichiense

NCBI ID

1799

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/010/726/245/GCA_010726245.1_ASM1072624v1

File for sequence-based predictions:
GCA_010726245.1_ASM1072624v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium aichiense is a member of the genus Mycolicibacterium, which is known for its association with various clinical implications. This microorganism has been implicated in infections primarily in immunocompromised individuals, where it can lead to serious health complications. Pulmonary infections are among the most notable disease associations, particularly in patients with underlying lung conditions or weakened immune systems. The pathogenicity of Mycolicibacterium aichiense is attributed to its ability to evade the immune response, which may involve mechanisms such as the modulation of host cell signaling pathways and the production of biofilms that protect it from phagocytosis. Furthermore, there is growing concern regarding antimicrobial resistance in Mycolicibacterium aichiense, as it has shown resistance to multiple classes of antibiotics, complicating treatment options for affected patients. This resistance is particularly alarming in the context of increasing rates of nosocomial infections, where the organism may be transmitted in healthcare settings. In terms of medical applications, while Mycolicibacterium aichiense itself is not used therapeutically, understanding its biology and interactions with the human host can inform the development of new strategies for managing infections caused by related mycobacterial species. Continued research into the epidemiology and clinical outcomes associated with Mycolicibacterium aichiense is essential for improving patient care and developing effective treatment protocols.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium aichiense is a species of bacteria that is primarily associated with soil environments and aquatic habitats. This microorganism thrives in nutrient-rich soils and is often found in areas with high organic matter content, such as decaying plant material and wetlands. Its ability to degrade complex organic compounds makes it an important player in the nutrient cycling processes within these ecosystems. In terms of ecological interactions, Mycolicibacterium aichiense is known to engage in symbiotic relationships with various plants, aiding in the breakdown of organic matter and enhancing soil fertility. This bacterium can also be found in association with other microorganisms, contributing to the overall microbial diversity and functionality of the soil microbiome. Additionally, Mycolicibacterium aichiense exhibits remarkable environmental adaptability, allowing it to survive in varying conditions, including fluctuations in moisture and temperature. Its presence in aquatic environments indicates its role in the degradation of organic pollutants, thus contributing to bioremediation efforts in contaminated water bodies. Overall, Mycolicibacterium aichiense plays a crucial role in maintaining the health and balance of its associated biomes, making it a significant organism in both terrestrial and aquatic ecosystems.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium aichiense has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to participate in biodegradation processes, making it valuable in the treatment of contaminated environments. For instance, Mycolicibacterium aichiense can effectively degrade complex organic compounds, which is crucial in waste treatment facilities aimed at reducing environmental pollutants. In the realm of biofuel production, Mycolicibacterium aichiense has been studied for its capacity to convert biomass into biofuels through fermentation processes. This capability allows for the transformation of agricultural waste into renewable energy sources, contributing to sustainable energy solutions. Moreover, the organism's unique metabolic pathways are being explored for pharmaceutical development, particularly in the synthesis of bioactive compounds. The enzymatic activities of Mycolicibacterium aichiense can lead to the production of novel antibiotics or other therapeutic agents, showcasing its potential in the pharmaceutical industry. Overall, Mycolicibacterium aichiense represents a promising candidate for various industrial applications, particularly in biodegradation, biofuel production, and pharmaceutical synthesis, highlighting its versatility and importance in modern biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	mistralai/mistral-7b-instruct	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	anthropic/claude-3-haiku:beta	google/gemini-pro	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	true	false	true	true	false	true	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true	false	false
Biofilm formation	N/A	true	true	true	false	true	true	false	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	false	false	true	false	false	true	false	true	true	true	true	false	false	false	false	false	false	true	true	false	false	false	false	true	true	false	false
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	false	true	false	true	true	true	true	true	true	true	false	false	true	true	false	false	true	true	false	false	false	false	true	true	false	false
Host association	TRUE	true ✓	false ✗	false ✗	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	spirillum ✗	spirillum ✗

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