Streptomyces apricus

General Information

Streptomyces apricus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most intriguing aspects of S. apricus is its potential in the field of natural product discovery. Members of the Streptomyces genus are well-known for their ability to produce a wide array of antibiotics, antifungals, and other bioactive compounds, and S. apricus is no exception. This species has been isolated from soil environments, which are rich in microbial diversity and competition, driving the evolution of unique metabolic pathways. The ability of S. apricus to synthesize novel compounds makes it a valuable subject for research in drug discovery and biotechnology. Researchers are particularly interested in its genome, which may harbor genes responsible for the biosynthesis of new and potentially therapeutic molecules. Another notable feature of S. apricus is its complex life cycle, which includes the formation of a mycelium and the production of spores. This life cycle is not only interesting from a biological standpoint but also has practical implications for its cultivation and use in industrial applications. The mycelial form allows for efficient colonization of substrates, which is advantageous for large-scale fermentation processes. In summary, Streptomyces apricus stands out due to its potential for producing novel bioactive compounds, its complex and adaptable life cycle, and its importance in natural product research. These characteristics make it a valuable organism for scientific study and biotechnological exploitation.

Streptomyces apricus is a fascinating actinobacterium known for its remarkable ability to produce a diverse array of bioactive compounds, including antibiotics and antifungal agents. This organism is part of the larger genus Streptomyces, which is renowned for its role in natural product biosynthesis. What makes S. apricus particularly interesting is its potential in pharmaceutical applications, as it has been shown to produce compounds that exhibit significant antimicrobial activity. One of the unique aspects of S. apricus is its ability to thrive in arid environments, which may contribute to its distinct metabolic pathways and the production of specialized metabolites that are not commonly found in other species. This adaptability to harsh conditions can lead to the discovery of novel compounds that could be harnessed for drug development. Additionally, S. apricus has been studied for its role in soil health and nutrient cycling, making it valuable not only in medicine but also in agriculture. Its interactions with plants and other soil microorganisms can enhance soil fertility and promote plant growth, highlighting its ecological importance. In summary, Streptomyces apricus stands out due to its antimicrobial properties, adaptation to extreme environments, and contribution to soil health, making it a significant organism for both research and practical applications in various fields.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces apricus

NCBI ID

1828112

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/008/369/065/GCF_008369065.1_ASM836906v1

File for sequence-based predictions:
GCF_008369065.1_ASM836906v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces apricus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. apricus itself is not commonly associated with human disease, its relatives are well-documented for their antimicrobial properties. This organism has been studied for its potential in producing novel antibiotics, which could be crucial in the fight against antimicrobial resistance (AMR). In terms of pathogenicity, S. apricus is generally considered non-pathogenic; however, the genus Streptomyces can occasionally be implicated in opportunistic infections, particularly in immunocompromised individuals. The ability of some Streptomyces species to evade the immune response through the production of various secondary metabolites may provide insights into their pathogenic potential. Moreover, the exploration of S. apricus in the context of probiotics and therapeutics is an area of interest, as certain strains within the genus have shown beneficial effects on human health, including modulation of the gut microbiota. The potential for developing vaccines or therapeutic agents from the metabolites of S. apricus is an exciting avenue for future research, particularly in the context of emerging infectious diseases and the need for new treatment options. Overall, while S. apricus may not have direct clinical implications as a pathogen, its contributions to antibiotic production and potential therapeutic applications underscore its relevance in the field of microbiology and medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces apricus is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to degrade complex organic compounds makes it an essential contributor to nutrient cycling within these biomes. Soil Biomes: In terrestrial ecosystems, Streptomyces apricus is often associated with nutrient-rich soils, particularly in agricultural settings. Here, it interacts with plant roots, promoting plant health through the production of various bioactive compounds. This relationship exemplifies a form of mutualism, where the bacteria benefit from the organic exudates of the plants while enhancing plant growth and resistance to pathogens. Decaying Organic Matter: This microorganism is also prevalent in compost heaps and forest floors, where it aids in the breakdown of leaf litter and other organic debris. By decomposing these materials, Streptomyces apricus contributes to the formation of humus, enriching the soil and supporting a diverse array of plant and microbial life. In addition to its role in decomposition, Streptomyces apricus is known for its ability to produce a variety of antibiotics and other bioactive compounds, which can inhibit the growth of competing microorganisms. This competitive advantage allows it to thrive in its ecological niche while also influencing the microbial community structure in its environment. Overall, Streptomyces apricus exemplifies the intricate relationships within soil ecosystems and highlights the importance of microbial diversity in maintaining ecological balance.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces apricus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Streptomyces apricus is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces apricus has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and reducing environmental pollution. Its enzymatic activity allows it to degrade various pollutants, making it a valuable asset in bioremediation efforts. Furthermore, Streptomyces apricus has potential applications in biofuel production. The organism can be involved in the conversion of biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. Overall, Streptomyces apricus stands out as a versatile microorganism with applications spanning pharmaceutical development, waste management, and biofuel production, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro	google/gemma-7b-it	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro-1.5	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	true	false	true	false	true	true	false	true	false	false	false	false	true	true	false	false	false	false	true	true	false	false	false	false
Host association	FALSE	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	N/A	N/A

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