Streptomyces hydrogenans

General Information

Streptomyces hydrogenans is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. hydrogenans is its ability to produce a wide array of antibiotics, making it a valuable organism in the field of pharmaceutical research. This species is particularly interesting due to its potential in bioremediation, as it can degrade various environmental pollutants, including complex organic compounds. Another unique aspect of S. hydrogenans is its role in promoting plant growth. It produces plant growth-promoting substances such as indole-3-acetic acid (IAA), which can enhance root development and overall plant health. This makes S. hydrogenans a candidate for use in sustainable agriculture as a biofertilizer. From a genetic perspective, S. hydrogenans has a large and complex genome, which is typical of the Streptomyces genus. This genetic complexity allows for the production of diverse and structurally complex secondary metabolites. The study of its genome can provide insights into the biosynthetic pathways of these compounds, which is crucial for the development of new antibiotics and other bioactive molecules. In summary, Streptomyces hydrogenans is a microorganism of significant interest due to its antibiotic production, bioremediation capabilities, and plant growth-promoting properties. Its genetic and metabolic versatility makes it a valuable subject for ongoing research in multiple scientific fields.

Streptomyces hydrogenans is a fascinating actinobacterium known for its unique metabolic capabilities, particularly its ability to utilize hydrogen as an energy source. This characteristic makes it a subject of interest in bioenergy research, as it could potentially contribute to sustainable hydrogen production processes. The organism is also notable for its role in the degradation of complex organic compounds, which positions it as a valuable player in bioremediation efforts, particularly in environments contaminated with organic pollutants. One of the most intriguing aspects of Streptomyces hydrogenans is its production of various secondary metabolites, including antibiotics and other bioactive compounds. These metabolites have significant implications for pharmaceutical research, as they may lead to the discovery of new drugs or therapeutic agents. The genetic and biochemical pathways involved in the synthesis of these compounds are of particular interest, providing insights into natural product biosynthesis. Furthermore, Streptomyces hydrogenans contributes to soil health and nutrient cycling, showcasing its ecological importance. Its ability to thrive in diverse environments highlights its adaptability and resilience, making it a model organism for studying microbial ecology and evolution. Overall, Streptomyces hydrogenans stands out not only for its unique metabolic traits but also for its potential applications in environmental and pharmaceutical sciences.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces hydrogenans

NCBI ID

1873719

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/014/656/075/GCA_014656075.1_ASM1465607v1

File for sequence-based predictions:
GCA_014656075.1_ASM1465607v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces hydrogenans is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. hydrogenans itself is not commonly associated with human disease, its relatives are crucial in the field of antimicrobial resistance research. The genus is known for its ability to produce a variety of secondary metabolites, including antibiotics such as streptomycin and tetracycline, which have been pivotal in treating bacterial infections. In terms of pathogenicity, Streptomyces species are generally considered non-pathogenic to humans; however, they can occasionally be implicated in opportunistic infections, particularly in immunocompromised individuals. The potential for these organisms to produce virulence factors and their ability to survive in various environments make them of interest in clinical microbiology. Moreover, the study of S. hydrogenans contributes to our understanding of immune evasion strategies employed by soil bacteria, which can inform the development of new therapeutic approaches. The organism's metabolic pathways and interactions with the human microbiome may also have implications for probiotic applications, although specific studies on S. hydrogenans are limited. Overall, while Streptomyces hydrogenans may not have direct clinical implications as a pathogen, its role in antibiotic production and potential contributions to antimicrobial resistance highlight its relevance in medical microbiology and therapeutic development.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces hydrogenans is a species of actinobacteria commonly found in various terrestrial environments, particularly in soil and decaying organic matter. This microorganism thrives in nutrient-rich habitats where it plays a crucial role in the decomposition process, contributing to nutrient cycling and soil health. Its ability to degrade complex organic compounds makes it an essential player in the terrestrial biome, particularly in temperate forests and grasslands where organic material is abundant. In these environments, Streptomyces hydrogenans engages in symbiotic relationships with plants, promoting plant growth through the production of growth-promoting substances. This interaction not only benefits the plants but also enhances the microbial diversity of the soil, creating a more resilient ecosystem. Additionally, Streptomyces hydrogenans is known for its ability to produce various bioactive compounds, which can inhibit the growth of competing microorganisms. This characteristic allows it to establish a niche within the microbial community, where it can thrive and exert its influence on the surrounding environment. Overall, the ecological role of Streptomyces hydrogenans in its native biomes underscores its importance in maintaining the health and balance of soil ecosystems, making it a vital organism in the study of soil microbiology and ecology.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces hydrogenans is known for its significant contributions to various industrial applications. One of the primary areas of interest is in biotechnology, where Streptomyces hydrogenans is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly noted for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces hydrogenans has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and the detoxification of contaminated environments. This property is especially valuable in the bioremediation of polluted sites, where the organism can help in the degradation of hazardous compounds. Moreover, Streptomyces hydrogenans has potential applications in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. The organism's enzymatic activity is crucial in breaking down lignocellulosic materials, making it a candidate for enhancing biofuel yield. In summary, Streptomyces hydrogenans plays a multifaceted role in pharmaceutical development, waste management, and biofuel production, showcasing its versatility and importance in various industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro-1.5	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	openchat/openchat-7b	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	google/gemma-7b-it	google/gemma-7b-it	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	false	true	false	true	false	true	false	false	true	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✗	coccus ✗

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