Streptomyces albidoflavus

General Information

Streptomyces albidoflavus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. albidoflavus is its ability to produce a wide array of antibiotics, making it a valuable organism in pharmaceutical research and biotechnology. This species is particularly interesting due to its production of compounds such as albidoflavin and other bioactive molecules that have potential therapeutic applications. Another unique feature of S. albidoflavus is its complex life cycle, which includes the formation of a mycelium and the production of spores. This life cycle is not only intriguing from a biological standpoint but also important for the industrial production of antibiotics, as the conditions that favor sporulation can influence metabolite production. In addition to its antibiotic production, S. albidoflavus has been studied for its role in soil health and plant growth promotion. It can act as a biocontrol agent against plant pathogens, thereby contributing to sustainable agriculture practices. The organism's ability to degrade complex organic materials also makes it a key player in nutrient cycling within soil ecosystems. From a genetic perspective, S. albidoflavus has a large and complex genome that encodes numerous biosynthetic gene clusters. These clusters are responsible for the synthesis of its diverse secondary metabolites. Advances in genomic and bioinformatic tools have allowed researchers to explore these gene clusters in detail, leading to the discovery of novel compounds and pathways. Overall, Streptomyces albidoflavus is a microorganism of significant interest due to its diverse metabolic capabilities, its role in natural and agricultural ecosystems, and its potential for biotechnological applications. Its study continues to provide insights into microbial ecology, genetics, and the development of new antibiotics and other bioactive compounds.

Streptomyces albidoflavus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its capacity to synthesize antibiotics, which are crucial in the fight against bacterial infections. The metabolites produced by S. albidoflavus have been shown to exhibit significant antimicrobial activity, highlighting its potential as a source for new therapeutic agents. One of the unique aspects of S. albidoflavus is its ability to thrive in diverse environments, including soil and decaying organic matter, which contributes to its role in nutrient cycling and soil health. This adaptability not only underscores its ecological importance but also enhances its potential for biotechnological applications. Additionally, S. albidoflavus has been studied for its antifungal properties, which further broadens its applicability in agriculture and medicine. The organism's genetic and metabolic pathways are of great interest to researchers aiming to understand the mechanisms behind its secondary metabolite production. This knowledge can lead to the development of novel compounds with therapeutic potential. In summary, Streptomyces albidoflavus stands out due to its antibiotic and antifungal production, ecological significance, and the potential for biotechnological advancements, making it a key player in both environmental and medical research.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces albidoflavus

NCBI ID

1886

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/359/525/GCA_000359525.1_ASM35952v1

File for sequence-based predictions:
GCA_000359525.1_ASM35952v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces albidoflavus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This microorganism has been studied for its potential in antimicrobial resistance due to its ability to produce various secondary metabolites that can inhibit the growth of pathogenic bacteria. Notably, it has been associated with the production of compounds such as antibiotics that can be effective against a range of bacterial infections, making it a valuable resource in the field of pharmaceutical development. In terms of human health, Streptomyces albidoflavus has been investigated for its potential use in probiotics and as a biocontrol agent in agriculture, which indirectly supports human health by reducing the reliance on chemical pesticides. However, its role in disease associations is less clear, as it is not typically recognized as a human pathogen. There have been rare instances where it has been isolated from clinical specimens, but these cases are not well-documented and do not indicate a direct pathogenicity. The organism's interaction with the human body is primarily through its metabolites rather than direct infection. Its immune evasion strategies are not well characterized, as it is not a common pathogen; however, its ability to produce a variety of bioactive compounds suggests a complex interaction with microbial communities. Overall, while Streptomyces albidoflavus is not primarily associated with infections in humans, its contributions to antibiotic production and potential applications in therapeutics highlight its importance in medical microbiology and public health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces albidoflavus is a filamentous bacterium commonly found in soil and decaying organic matter. This microorganism thrives in a variety of terrestrial ecosystems, particularly in nutrient-rich environments where organic decomposition occurs. Its presence is often associated with agricultural soils, where it plays a crucial role in the breakdown of complex organic materials, contributing to nutrient cycling and soil health. In these soil ecosystems, S. albidoflavus engages in antibiotic production, which helps it compete with other microorganisms for resources. This ability not only aids in its survival but also influences the microbial community structure, promoting a diverse ecosystem. The production of antibiotics can inhibit the growth of pathogenic bacteria, thus playing a significant role in biocontrol and plant health. Additionally, S. albidoflavus is known for its symbiotic relationships with various plants. It can enhance plant growth by improving nutrient availability through its metabolic activities. This interaction exemplifies the importance of this microorganism in agricultural biomes, where it contributes to sustainable farming practices by reducing the need for chemical fertilizers and pesticides. Overall, Streptomyces albidoflavus is a vital component of soil biomes, influencing both the physical and biological properties of its environment, and showcasing the intricate relationships that exist within terrestrial ecosystems.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces albidoflavus is known for its significant contributions to various industrial applications. One of the primary areas is in biotechnology, where it is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly noted for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces albidoflavus has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and the detoxification of contaminated environments. This property is especially valuable in the remediation of polluted sites, where the organism can help in the degradation of hazardous compounds. Moreover, Streptomyces albidoflavus is also explored for its potential in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. In pharmaceutical development, the secondary metabolites produced by Streptomyces albidoflavus have been investigated for their therapeutic properties, leading to the discovery of new drugs and treatments. The organism's ability to produce unique compounds makes it a valuable resource in the pharmaceutical industry. Overall, Streptomyces albidoflavus exemplifies the versatility of microbial applications across various industries, showcasing its importance in biotechnology, waste management, biofuel production, and pharmaceutical development.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/gemini-flash-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	google/gemma-7b-it	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	google/gemini-pro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	true	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	false	false	true	true	true	false	true	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	false	false	true	true
Host association	FALSE	true ✗	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Plant pathogenicity	FALSE	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

Back to Search