Pseudomonas pharmacofabricae

General Information

Pseudomonas pharmacofabricae is a fascinating microorganism that has garnered significant interest in the scientific community due to its unique metabolic capabilities and potential applications in biotechnology. This bacterium is part of the Pseudomonas genus, which is well-known for its diverse metabolic pathways and ability to thrive in various environments, including soil, water, and plant surfaces. One of the most intriguing aspects of Pseudomonas pharmacofabricae is its ability to produce a wide range of bioactive compounds. These compounds have shown potential in pharmaceutical applications, particularly as antibiotics, antifungals, and anticancer agents. The production of these bioactive molecules is often regulated by complex genetic networks, making this bacterium a valuable model for studying gene regulation and secondary metabolite biosynthesis. Additionally, Pseudomonas pharmacofabricae exhibits a remarkable capacity for bioremediation. It can degrade various environmental pollutants, including hydrocarbons and heavy metals, making it a promising candidate for cleaning up contaminated sites. This ability is attributed to its versatile enzymatic machinery, which can break down complex organic compounds into less harmful substances. From a research perspective, Pseudomonas pharmacofabricae is also notable for its genetic plasticity. It can acquire and exchange genetic material through horizontal gene transfer, which contributes to its adaptability and resilience in changing environments. This characteristic makes it an excellent subject for studying microbial evolution and the mechanisms of genetic exchange. In summary, Pseudomonas pharmacofabricae stands out due to its bioactive compound production, bioremediation potential, and genetic adaptability. These features not only make it a valuable organism for scientific research but also highlight its potential applications in medicine and environmental management.

Pseudomonas pharmacofabricae is a fascinating bacterium known for its remarkable ability to produce a variety of bioactive compounds, making it a valuable organism in pharmaceutical research. This species is particularly interesting due to its potential in the bioproduction of antibiotics and other therapeutic agents. Its metabolic versatility allows it to thrive in diverse environments, including soil and water, where it can utilize a wide range of organic compounds as carbon sources. One of the standout features of Pseudomonas pharmacofabricae is its capacity for bioremediation. This organism can degrade various environmental pollutants, including hydrocarbons and heavy metals, which positions it as a key player in environmental cleanup efforts. Researchers are actively exploring its genetic and enzymatic pathways to enhance its efficiency in bioremediation applications. Additionally, Pseudomonas pharmacofabricae has garnered attention for its role in plant health. It has been shown to promote plant growth and enhance resistance to pathogens, making it a candidate for use in sustainable agriculture. The mechanisms behind its plant growth-promoting properties are an area of active investigation, with implications for developing eco-friendly agricultural practices. Overall, Pseudomonas pharmacofabricae stands out not only for its biotechnological applications but also for its ecological significance, making it a subject of interest for microbiologists, ecologists, and biotechnologists alike.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Pseudomonadales

Family: Pseudomonadaceae

Genus: Pseudomonas

Species: Pseudomonas pharmacofabricae

NCBI ID

1905276

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/002/835/605/GCF_002835605.1_ASM283560v1

File for sequence-based predictions:
GCF_002835605.1_ASM283560v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Pseudomonas pharmacofabricae is a member of the Pseudomonas genus, which is known for its environmental versatility and clinical significance. This bacterium has been associated with various clinical implications, particularly in the context of infections and antimicrobial resistance. It is recognized for its ability to cause opportunistic infections, especially in immunocompromised patients, leading to conditions such as pneumonia, sepsis, and wound infections. The pathogenicity of Pseudomonas pharmacofabricae is attributed to its production of virulence factors, including exotoxins and biofilm formation, which facilitate its adherence to surfaces and evasion of the host's immune response. Moreover, this organism exhibits significant antimicrobial resistance mechanisms, making infections difficult to treat. It often harbors genes that confer resistance to multiple classes of antibiotics, including beta-lactams and aminoglycosides, which complicates therapeutic options. The presence of such resistance genes is a growing concern in clinical settings, as it can lead to treatment failures and increased morbidity. In terms of medical applications, while Pseudomonas pharmacofabricae is not typically used as a probiotic or therapeutic agent, understanding its mechanisms of pathogenicity and resistance can inform the development of new treatment strategies and infection control measures. Its role in outbreaks, particularly in healthcare settings, underscores the need for vigilant monitoring and effective infection prevention protocols to mitigate its impact on patient health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Pseudomonas pharmacofabricae is a bacterium commonly associated with various soil environments and plant-associated habitats. This microorganism thrives in nutrient-rich soils, particularly those that are disturbed or have been subjected to agricultural practices. Its ability to degrade organic compounds makes it a vital player in the soil ecosystem, contributing to nutrient cycling and organic matter decomposition. In these soil environments, Pseudomonas pharmacofabricae often engages in symbiotic relationships with plant roots, promoting plant health through mechanisms such as nutrient solubilization and pathogen suppression. This interaction not only enhances plant growth but also improves soil structure and fertility, making it an important organism in sustainable agriculture. Additionally, Pseudomonas pharmacofabricae is known for its adaptability to various environmental conditions, including the presence of pollutants. It can metabolize a wide range of organic compounds, which allows it to thrive in contaminated soils and contribute to bioremediation efforts. This capability underscores its role in maintaining ecological balance and promoting the health of terrestrial ecosystems. Overall, Pseudomonas pharmacofabricae plays a crucial role in soil health, plant growth promotion, and environmental remediation, making it a significant microorganism in both natural and agricultural biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Pseudomonas pharmacofabricae has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where this organism is utilized for its ability to produce a range of valuable metabolites through fermentation. This process can lead to the development of bioactive compounds that have pharmaceutical relevance, including antibiotics and other therapeutic agents. In the realm of waste management, Pseudomonas pharmacofabricae is recognized for its capacity to degrade environmental pollutants. This includes the breakdown of complex organic compounds, making it a candidate for bioremediation efforts aimed at cleaning contaminated sites. Its enzymatic activity allows it to metabolize harmful substances, thus contributing to more sustainable waste treatment solutions. Furthermore, this microorganism has been explored for its role in biofuel production. Through fermentation processes, Pseudomonas pharmacofabricae can convert biomass into biofuels, providing an alternative energy source that is more environmentally friendly compared to fossil fuels. In pharmaceutical development, the unique metabolic pathways of Pseudomonas pharmacofabricae can be harnessed to synthesize complex molecules that are difficult to produce chemically. This includes the production of enzymes that can be used in drug formulation and development, enhancing the efficacy and delivery of therapeutic agents. Overall, Pseudomonas pharmacofabricae demonstrates a versatile profile that supports its use across multiple industries, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its importance in advancing sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	anthropic/claude-3-haiku:beta	google/gemini-pro	mistralai/mistral-7b-instruct	google/palm-2-chat-bison-32k	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	google/gemma-7b-it	google/gemma-7b-it	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/gemini-flash-1.5	google/gemini-flash-1.5	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	true	false	false	false	false	true	true	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	false	false	true	true	true	false	true	true	false	false	false	false	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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