Streptomyces microflavus

General Information

Streptomyces microflavus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. microflavus is its ability to produce a wide array of antibiotics and bioactive compounds. This makes it a valuable organism in the field of biotechnology and pharmaceutical research. Streptomyces species are known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their unique colony morphology. The production of geosmin by S. microflavus is particularly interesting, as this compound is responsible for the earthy smell of soil. This characteristic not only highlights the organism's ecological role but also its potential applications in environmental monitoring and soil health assessment. Moreover, S. microflavus has been studied for its potential in bioremediation due to its ability to degrade various organic pollutants. Its enzymatic repertoire includes a variety of hydrolases, oxidoreductases, and lyases, which enable it to break down complex organic molecules. This makes it a promising candidate for the development of sustainable environmental cleanup strategies. In addition to its environmental and pharmaceutical applications, S. microflavus is also of interest in agricultural research. It has been shown to produce plant growth-promoting substances and can act as a biocontrol agent against plant pathogens. This dual role enhances its value in developing eco-friendly agricultural practices. Overall, Streptomyces microflavus stands out due to its diverse metabolic capabilities, ecological significance, and potential applications in various industries. Its study continues to provide insights into microbial ecology, natural product biosynthesis, and innovative biotechnological applications.

Streptomyces microflavus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, which makes it a significant organism in the field of natural product research. This species is particularly interesting due to its capacity to synthesize antibiotics, including those effective against various pathogenic bacteria, which has implications for developing new therapeutic agents in the fight against antibiotic resistance. One of the unique characteristics of S. microflavus is its ability to produce yellow pigments, which are not only visually striking but also suggest potential applications in biotechnology and pharmaceuticals. These pigments may have antioxidant properties, making them valuable for further exploration in health-related applications. Additionally, S. microflavus is part of a larger group of Streptomyces species that are known for their complex life cycles and ability to thrive in diverse environments, including soil and decaying organic matter. This adaptability contributes to its ecological role in nutrient cycling and soil health, highlighting its importance in environmental microbiology. Research on S. microflavus can also provide insights into the genetic and metabolic pathways involved in secondary metabolite production, which is crucial for biotechnological applications. The organism's genetic makeup can be manipulated to enhance the production of desired compounds, making it a valuable tool for synthetic biology and drug discovery. In summary, Streptomyces microflavus stands out due to its antibiotic production, unique pigmentation, and its role in natural product biosynthesis, making it a subject of interest for researchers aiming to harness its capabilities for medical and environmental applications.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces microflavus

NCBI ID

1919

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/013/364/315/GCA_013364315.1_ASM1336431v1

File for sequence-based predictions:
GCA_013364315.1_ASM1336431v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces microflavus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. This species has been studied for its potential in antimicrobial resistance and its ability to produce various secondary metabolites that may have therapeutic applications. Clinical implications of Streptomyces microflavus include its involvement in the natural microbiota of soil and its potential to influence human health through the production of beneficial compounds. It has been noted for its ability to produce antibiotics such as actinomycin, which can be effective against certain bacterial infections. However, there is limited documentation regarding its direct pathogenicity in humans. While some Streptomyces species are known to cause infections in immunocompromised individuals, Streptomyces microflavus has not been conclusively linked to any specific human disease or outbreak. In terms of immune evasion strategies, Streptomyces microflavus does not exhibit known mechanisms that directly affect human immune responses, but its production of bioactive compounds may influence microbial communities and host interactions. Overall, while Streptomyces microflavus holds promise in the field of therapeutics and probiotics, further research is needed to fully understand its clinical relevance and potential applications in medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces microflavus is a species of actinobacteria commonly found in soil and decaying organic matter. This microorganism thrives in a variety of terrestrial biomes, particularly in nutrient-rich environments where organic decomposition occurs. Its presence is often associated with temperate forests and grasslands, where it plays a crucial role in the breakdown of complex organic materials, contributing to nutrient cycling and soil health. In these environments, Streptomyces microflavus exhibits antibiotic production, which not only helps it compete with other microorganisms but also influences the microbial community structure. This ability to produce bioactive compounds allows it to establish a niche where it can thrive while simultaneously suppressing potential pathogens. Additionally, Streptomyces microflavus is known for its interactions with plant roots, where it can form mutualistic relationships. These interactions can enhance plant growth by improving nutrient availability and providing protection against soil-borne diseases. Such symbiotic relationships are particularly important in agricultural ecosystems, where the use of microbial inoculants can lead to improved crop yields and soil fertility. Overall, Streptomyces microflavus is a vital component of its ecological niche, contributing to the health of soil ecosystems and playing a significant role in the sustainability of agricultural practices.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces microflavus is known for its significant contributions to various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly valuable in the fermentation process, where it can be harnessed to synthesize important pharmaceuticals, such as streptomycin, which is crucial in treating bacterial infections. In the realm of waste management, Streptomyces microflavus has demonstrated potential in biodegradation processes. It can break down complex organic materials, making it useful in the treatment of contaminated soils and wastewater. This capability not only helps in reducing environmental pollutants but also contributes to the recycling of nutrients back into the ecosystem. Furthermore, Streptomyces microflavus plays a role in biofuel production. Its enzymatic activity can facilitate the breakdown of lignocellulosic biomass, which is a critical step in the conversion of plant materials into fermentable sugars for bioethanol production. This process is essential for developing sustainable energy sources. In summary, Streptomyces microflavus is a versatile microorganism with applications spanning pharmaceutical development, biotechnology, waste management, and biofuel production, showcasing its importance in various industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/gemini-pro	meta-llama/llama-3-70b-instruct:nitro	anthropic/claude-3.5-sonnet	mistralai/mistral-7b-instruct	mistralai/mixtral-8x7b-instruct:nitro	anthropic/claude-3-haiku:beta	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/gemma-7b-it	google/gemma-7b-it	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	false	true	true	true	true	true	false	false	false	false	false	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✗	coccus ✗

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