Acinetobacter chinensis

General Information

Acinetobacter chinensis is a fascinating microorganism that belongs to the genus Acinetobacter, which is known for its remarkable adaptability and resilience in various environments. One of the most intriguing aspects of A. chinensis is its ability to thrive in diverse ecological niches, ranging from soil and water to hospital settings. This adaptability makes it a subject of significant interest in both environmental and clinical microbiology. One of the key characteristics of A. chinensis is its potential for bioremediation. It has been studied for its ability to degrade various pollutants, including hydrocarbons and heavy metals, making it a valuable candidate for cleaning up contaminated environments. This capability is particularly important in the context of increasing industrial pollution and the need for sustainable environmental management practices. Another notable feature of A. chinensis is its role in antibiotic resistance research. Like many members of the Acinetobacter genus, A. chinensis has been found to possess multiple antibiotic resistance genes. This makes it a critical organism for studying the mechanisms of resistance and for developing new strategies to combat antibiotic-resistant infections. The presence of these resistance genes also highlights the importance of monitoring and controlling the spread of such organisms in healthcare settings. In addition to its environmental and clinical significance, A. chinensis is also of interest due to its metabolic versatility. It can utilize a wide range of substrates for growth, which is indicative of its robust metabolic pathways. This versatility not only underscores its adaptability but also opens up possibilities for its use in various biotechnological applications, such as the production of biofuels and bioplastics. Overall, Acinetobacter chinensis is a microorganism that stands out due to its environmental resilience, bioremediation potential, antibiotic resistance, and metabolic versatility. These characteristics make it a valuable subject for ongoing research in multiple scientific disciplines.

Acinetobacter chinensis is a notable member of the Acinetobacter genus, which is known for its environmental versatility and ability to thrive in diverse habitats. This species has garnered attention due to its emerging role in clinical settings, particularly as an opportunistic pathogen in immunocompromised individuals. Its resilience to various antibiotics makes it a subject of interest in antimicrobial resistance research, highlighting the need for ongoing studies to understand its resistance mechanisms and potential treatment options. One of the unique aspects of A. chinensis is its genetic adaptability, which allows it to acquire resistance genes from other bacteria. This characteristic not only complicates treatment strategies but also raises concerns about its potential to spread resistance traits within microbial communities. Furthermore, A. chinensis has been isolated from various environments, including soil and water, indicating its ecological significance and potential role in biogeochemical cycles. Research into A. chinensis can provide valuable insights into the evolution of resistance in bacteria, as well as the dynamics of microbial populations in both clinical and environmental contexts. Its ability to survive in harsh conditions and its interactions with other microorganisms make it a fascinating subject for studies in microbial ecology and pathogenesis. Overall, Acinetobacter chinensis represents a critical area of study for understanding the complexities of bacterial resistance and the implications for public health.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter chinensis

NCBI ID

2004650

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/002/165/375/GCF_002165375.2_ASM216537v2

File for sequence-based predictions:
GCF_002165375.2_ASM216537v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Acinetobacter chinensis is a member of the Acinetobacter genus, which is known for its clinical significance, particularly in hospital settings. This bacterium is associated with various infections, including pneumonia, bloodstream infections, and wound infections, especially in immunocompromised patients. Its role in human health is complex, as it can be part of the normal skin flora but also has the potential to become pathogenic under certain conditions. One of the major concerns regarding Acinetobacter chinensis is its antimicrobial resistance. This organism has shown resistance to multiple classes of antibiotics, including beta-lactams and aminoglycosides, which complicates treatment options. The mechanisms of resistance often involve the production of beta-lactamases and efflux pumps, making it a significant challenge in clinical settings. In terms of immune evasion, Acinetobacter chinensis can alter its surface structures to avoid detection by the host's immune system, contributing to its pathogenicity. This ability to evade the immune response is critical in its role as a nosocomial pathogen, where it can persist in the hospital environment and infect vulnerable patients. While Acinetobacter chinensis is primarily recognized for its pathogenic potential, there is ongoing research into its potential applications in biotechnology and medicine. Some strains of Acinetobacter species are being explored for their ability to produce useful metabolites or for their role in bioremediation. However, the clinical implications of Acinetobacter chinensis remain a significant concern, particularly in the context of increasing antibiotic resistance and the need for effective infection control measures in healthcare settings.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter chinensis is a versatile bacterium commonly found in various habitat types across different biomes. This microorganism is particularly associated with urban environments, where it thrives in soil and water contaminated with organic matter and nutrients. Its ability to adapt to diverse conditions allows it to inhabit hospital settings, where it can be found on surfaces and in medical equipment, contributing to its role as an opportunistic pathogen in human health contexts. In natural ecosystems, Acinetobacter chinensis plays a significant role in nutrient cycling, particularly in the degradation of organic compounds. This bacterium is known for its ability to metabolize a wide range of substrates, which aids in the breakdown of pollutants and contributes to bioremediation efforts in contaminated environments. Its presence in aquatic ecosystems highlights its adaptability, as it can survive in both freshwater and marine environments, often found in biofilms on submerged surfaces. Furthermore, Acinetobacter chinensis exhibits notable interactions with its surroundings, including symbiotic relationships with other microorganisms. These interactions can enhance nutrient availability and promote microbial diversity within the ecosystem. Its resilience to environmental stressors, such as antibiotic pressure and nutrient limitation, underscores its ecological significance and adaptability in various biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter chinensis has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Acinetobacter chinensis is utilized for its ability to produce enzymes that can be harnessed in biocatalysis processes. These enzymes are valuable in the synthesis of pharmaceuticals and other chemical compounds, enhancing the efficiency and specificity of reactions. In the realm of waste management, Acinetobacter chinensis has demonstrated capabilities in biodegradation, particularly in the breakdown of pollutants such as hydrocarbons and heavy metals. This makes it a candidate for use in bioremediation strategies aimed at cleaning contaminated environments, such as oil spills or industrial waste sites. Furthermore, the organism has been explored for its role in biofuel production. Through fermentation processes, Acinetobacter chinensis can convert organic substrates into biofuels, contributing to sustainable energy solutions. Its metabolic pathways allow for the efficient conversion of waste materials into usable energy, thus supporting circular economy initiatives. In pharmaceutical development, the unique metabolic properties of Acinetobacter chinensis can be leveraged for the production of bioactive compounds. These compounds may have therapeutic potential, making the organism a subject of interest in drug discovery and development. Overall, Acinetobacter chinensis presents a versatile platform for various industrial applications, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its importance in advancing sustainable practices and innovative solutions in these fields.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	google/gemma-7b-it	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	google/gemini-flash-1.5	google/gemini-flash-1.5	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	false	true	true	false	true	true	false	true	true	false	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Biosafety level	N/A	biosafety level 2	biosafety level 1	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 1	biosafety level 1	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2
Health association	N/A	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	false	true	true	true	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma ✓	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha ✗	alpha ✗	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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