Streptomyces geranii

General Information

Streptomyces geranii is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. geranii is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable subject of study in pharmaceutical research and biotechnology. The genus Streptomyces is well-known for its complex life cycle and filamentous growth, which resembles that of fungi. S. geranii forms a dense, branched mycelium that can differentiate into spores, contributing to its resilience and adaptability in various environments. Another intriguing aspect of S. geranii is its ecological role. It is commonly found in soil, where it plays a crucial part in the decomposition of organic matter, thereby contributing to nutrient cycling and soil health. The ability of S. geranii to degrade complex organic compounds makes it an important organism for environmental sustainability and bioremediation efforts. From a genetic perspective, S. geranii possesses a large and complex genome, which encodes for numerous biosynthetic gene clusters. These clusters are responsible for the synthesis of its diverse secondary metabolites. The study of these gene clusters not only helps in understanding the biosynthetic pathways but also opens up possibilities for genetic engineering to enhance the production of valuable compounds. In summary, Streptomyces geranii is a microorganism of significant interest due to its prolific production of bioactive compounds, its role in environmental sustainability, and its genetic potential for biotechnological applications. Its unique characteristics make it a valuable model organism for research in various scientific fields.

Streptomyces geranii is a fascinating actinobacterium known for its unique ecological role and potential applications in biotechnology. This microorganism is primarily isolated from soil and is part of the diverse genus Streptomyces, which is renowned for its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and immunosuppressants. What makes S. geranii particularly interesting is its ability to synthesize novel secondary metabolites that may have therapeutic potential. One of the standout features of S. geranii is its capacity to degrade complex organic materials, which plays a crucial role in nutrient cycling within its natural habitat. This ability not only contributes to soil health but also positions S. geranii as a potential candidate for bioremediation efforts, particularly in environments contaminated with organic pollutants. Additionally, research into S. geranii has revealed its potential in agricultural applications, particularly in the development of biopesticides. The compounds produced by this organism can inhibit the growth of plant pathogens, offering a sustainable alternative to chemical pesticides. This characteristic underscores the importance of S. geranii in promoting sustainable agricultural practices. Furthermore, the genetic and metabolic pathways of S. geranii are of significant interest to researchers studying microbial diversity and the evolution of secondary metabolite production. Understanding these pathways can lead to the discovery of new compounds with pharmaceutical applications, making S. geranii a valuable organism in the field of natural product research. Overall, Streptomyces geranii exemplifies the intricate relationship between microorganisms and their environments, highlighting their potential contributions to health, agriculture, and environmental sustainability.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces geranii

NCBI ID

2058923

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/002/954/775/GCF_002954775.1_ASM295477v1

File for sequence-based predictions:
GCF_002954775.1_ASM295477v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces geranii is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. geranii itself is not commonly associated with human disease, its relatives have been implicated in various clinical contexts. Antimicrobial resistance is a notable concern, as some Streptomyces species can harbor genes that confer resistance to multiple classes of antibiotics, complicating treatment options for infections caused by other pathogens. In terms of human health, Streptomyces species, including S. geranii, are often studied for their potential as probiotics and their role in maintaining a balanced microbiome. They can produce metabolites that may have beneficial effects on human health, such as immunomodulatory properties. Furthermore, the ability of Streptomyces to produce a wide array of secondary metabolites makes it a valuable organism in the field of pharmaceutical development. Research into S. geranii may lead to the discovery of novel compounds that could be used in therapeutics or as alternatives to traditional antibiotics. Overall, while Streptomyces geranii may not be directly linked to specific outbreaks or infections, its broader implications in antimicrobial resistance, pharmaceutical applications, and potential health benefits underscore its relevance in clinical microbiology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces geranii is a species of actinobacteria that is primarily associated with soil ecosystems and plant rhizospheres. This microorganism thrives in nutrient-rich environments, often found in areas with abundant organic matter, such as decaying plant material and compost. Its presence is particularly notable in agricultural soils, where it plays a crucial role in nutrient cycling and soil health. Ecological Niches: - Streptomyces geranii is known for its ability to decompose complex organic compounds, contributing to the breakdown of organic matter and the release of essential nutrients back into the soil. This process enhances soil fertility and supports plant growth. - The organism is also involved in the production of various secondary metabolites, including antibiotics, which can inhibit the growth of pathogenic microorganisms, thus promoting a healthier soil microbiome. Habitat Features: - This bacterium is commonly found in temperate and tropical regions, where the soil is rich in organic content. It prefers well-drained soils that are not overly saturated with water, as excessive moisture can hinder its growth. - Streptomyces geranii can also be isolated from plant roots, where it forms beneficial relationships with plants. This symbiotic interaction can enhance plant resistance to diseases and improve nutrient uptake, showcasing its role in plant-microbe interactions. Environmental Adaptations: - The ability of Streptomyces geranii to produce spores allows it to survive in harsh environmental conditions, including periods of drought or nutrient scarcity. This adaptation is vital for its persistence in fluctuating soil environments. - Furthermore, its metabolic versatility enables it to utilize a wide range of organic substrates, making it well-suited for diverse ecological niches within the soil biome. In summary, Streptomyces geranii is a vital component of soil ecosystems, contributing to nutrient cycling, plant health, and overall soil quality through its ecological roles and interactions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces geranii has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Streptomyces geranii is utilized for its ability to produce a wide range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Streptomyces geranii has demonstrated capabilities in biodegradation, where it can break down complex organic materials, thus aiding in the treatment of waste and reducing environmental pollution. This property is especially valuable in the degradation of pollutants and in the bioremediation of contaminated sites. Furthermore, Streptomyces geranii is being explored for its potential in biofuel production. The organism's metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. In summary, Streptomyces geranii is a versatile microorganism with applications spanning pharmaceutical development, waste management, and biofuel production, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4	openai/gpt-4	openchat/openchat-7b	openchat/openchat-7b	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerotolerant ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	false	false
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	true	true	true	true	false	true	false	false	true	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	TRUE	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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