Streptomyces cahuitamycinicus

General Information

Streptomyces cahuitamycinicus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most intriguing aspects of S. cahuitamycinicus is its ability to produce cahuitamycins, a novel class of antibiotics. These compounds have shown significant potential in combating biofilm-associated infections, which are notoriously difficult to treat with conventional antibiotics. The discovery of cahuitamycins highlights the importance of S. cahuitamycinicus in the search for new antimicrobial agents, especially in the era of increasing antibiotic resistance. Another unique feature of S. cahuitamycinicus is its complex life cycle, which includes the formation of mycelium and spores. This characteristic is typical of the Streptomyces genus and contributes to its ability to thrive in diverse environments, including soil and marine ecosystems. The organism's ability to produce a wide array of enzymes also makes it valuable for biotechnological applications, such as the degradation of organic matter and the production of bioactive compounds. In summary, Streptomyces cahuitamycinicus is a microorganism of significant interest due to its production of novel antibiotics, its complex developmental biology, and its potential applications in biotechnology. Its study not only advances our understanding of microbial diversity and secondary metabolism but also holds promise for the development of new therapeutic agents.

Streptomyces cahuitamycinicus is a fascinating actinobacterium notable for its ability to produce a variety of bioactive compounds, particularly antibiotics. This species is part of the Streptomyces genus, which is renowned for its prolific secondary metabolite production, making it a significant player in pharmaceutical research and development. One of the most interesting aspects of S. cahuitamycinicus is its potential in the discovery of novel antimicrobial agents, which is crucial in the ongoing battle against antibiotic-resistant pathogens. The organism was first isolated from soil samples in the Cahuita National Park in Costa Rica, highlighting its ecological niche and the importance of biodiversity in drug discovery. Its unique habitat contributes to the distinct metabolic pathways that may lead to the synthesis of compounds not found in other Streptomyces species. Research on S. cahuitamycinicus has revealed its capability to produce cahuitamycin, a compound with promising antibacterial properties. This underscores the organism's potential as a source of new therapeutic agents. Furthermore, the genetic and biochemical pathways involved in the biosynthesis of these compounds are of great interest to researchers, as they can provide insights into the mechanisms of natural product formation. In summary, Streptomyces cahuitamycinicus stands out not only for its ecological significance but also for its potential contributions to medicine, making it a valuable subject for ongoing research in microbiology and pharmacology.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces cahuitamycinicus

NCBI ID

2070367

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/002/891/435/GCF_002891435.1_ASM289143v1

File for sequence-based predictions:
GCF_002891435.1_ASM289143v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces cahuitamycinicus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While specific clinical implications of S. cahuitamycinicus are not extensively documented, its relatives have been associated with various important clinical applications. Antibiotic production is a hallmark of this genus, with many species contributing to the development of drugs used to treat bacterial infections. This highlights the potential of S. cahuitamycinicus in the field of antimicrobial therapy. In terms of pathogenicity, members of the Streptomyces genus are generally considered non-pathogenic to humans; however, they can be opportunistic pathogens in immunocompromised individuals. The ability of some Streptomyces species to produce a wide range of secondary metabolites suggests that S. cahuitamycinicus may also possess similar capabilities, which could be harnessed for therapeutic purposes. Moreover, the organism's role in antimicrobial resistance is an area of interest, as the production of antibiotics by Streptomyces species can lead to the emergence of resistant strains. Understanding the mechanisms of resistance in related species may provide insights into the potential challenges posed by S. cahuitamycinicus in clinical settings. In summary, while direct clinical implications of Streptomyces cahuitamycinicus are not well-established, its potential contributions to antibiotic production, immune response modulation, and the understanding of antimicrobial resistance mechanisms make it a relevant organism in the context of human health and disease management.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces cahuitamycinicus is a species of actinobacteria that is primarily associated with soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its presence is often linked to tropical and subtropical biomes, particularly in regions with high humidity and temperature, which facilitate its growth and metabolic activities. In these soil habitats, S. cahuitamycinicus contributes to nutrient cycling by breaking down complex organic compounds, thus releasing essential nutrients back into the soil. This process not only enriches the soil but also supports the growth of plants and other microorganisms, highlighting its role as a key player in soil health. Additionally, S. cahuitamycinicus is known for its ability to produce various bioactive compounds, including antibiotics, which can inhibit the growth of competing microbial species. This characteristic allows it to establish a competitive advantage in its niche, further influencing the microbial community structure within its habitat. The interactions of S. cahuitamycinicus with its environment exemplify the intricate relationships found in terrestrial ecosystems, where microorganisms contribute to both the stability and diversity of the biome. Its adaptations to specific environmental conditions, such as moisture levels and organic content, underscore its ecological significance and the importance of microbial diversity in maintaining ecosystem functions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces cahuitamycinicus has shown significant potential in various industrial applications. One of the most notable areas is in pharmaceutical development, where it is known for its ability to produce bioactive compounds, including antibiotics and other therapeutic agents. This capability is largely attributed to its unique metabolic pathways and enzyme production, which can lead to the synthesis of complex molecules that are valuable in medicine. In addition to its pharmaceutical uses, Streptomyces cahuitamycinicus plays a role in biotechnology through its involvement in fermentation processes. This organism can be utilized to ferment various substrates, leading to the production of secondary metabolites that have applications in food preservation and flavor enhancement. Moreover, this microorganism is also being explored for its potential in waste management. Its ability to degrade complex organic materials makes it a candidate for biodegradation processes, where it can help in the breakdown of pollutants and contribute to environmental cleanup efforts. Lastly, there is growing interest in the use of Streptomyces cahuitamycinicus in biofuel production. Its metabolic capabilities may allow for the conversion of biomass into biofuels, providing a sustainable alternative to fossil fuels. Overall, the diverse applications of Streptomyces cahuitamycinicus highlight its importance in various industrial sectors, particularly in enhancing sustainability and developing new therapeutic agents.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Animal pathogenicity	N/A	false	false	false	false	false	false	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	false	true	true	true	false	true	false	false	true	true	true	true	true	true	true	true	false	false	true	true	true	true	false	false
Host association	FALSE	true ✗	false ✓	true ✗	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	spirillum ✗	spirillum ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗

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