Streptomyces cadmiisoli

General Information

Streptomyces cadmiisoli is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites, including antibiotics, antifungals, and antitumor agents. One of the most intriguing aspects of S. cadmiisoli is its ability to thrive in heavy metal-contaminated soils, particularly those with high concentrations of cadmium. This unique adaptation not only makes it a subject of interest for environmental microbiologists but also positions it as a potential candidate for bioremediation efforts aimed at detoxifying polluted environments. In addition to its environmental resilience, S. cadmiisoli is notable for its complex life cycle, which includes the formation of a mycelial network and the production of spores. This life cycle is characteristic of the Streptomyces genus and contributes to its ability to colonize diverse ecological niches. Moreover, the secondary metabolites produced by S. cadmiisoli are of significant interest to pharmaceutical research. The genus Streptomyces is already well-known for its role in the discovery of antibiotics such as streptomycin and tetracycline, and S. cadmiisoli is no exception. The potential for discovering novel bioactive compounds from this species could lead to the development of new therapeutic agents, particularly in an era where antibiotic resistance is a growing concern. In summary, Streptomyces cadmiisoli stands out due to its remarkable ability to survive in heavy metal-laden environments, its complex developmental biology, and its potential to contribute to the discovery of new pharmaceuticals. These characteristics make it a valuable organism for both environmental and medical research.

Streptomyces cadmiisoli is a fascinating actinobacterium that has garnered attention due to its unique ability to thrive in cadmium-contaminated environments. This microorganism is particularly interesting because it exhibits heavy metal resistance, allowing it to survive and proliferate in soils with high levels of cadmium, a toxic heavy metal that poses significant environmental and health risks. Its resilience to such harsh conditions makes it a valuable candidate for bioremediation efforts aimed at detoxifying contaminated soils and water bodies. One of the standout features of S. cadmiisoli is its potential to produce a variety of bioactive compounds, which are of great interest in pharmaceutical research. These compounds can include antibiotics and other secondary metabolites that may have therapeutic applications. The ability to produce such compounds while simultaneously detoxifying heavy metals highlights the organism's dual utility in both environmental and medical fields. Furthermore, the genetic and metabolic pathways that enable S. cadmiisoli to resist cadmium toxicity are subjects of ongoing research. Understanding these mechanisms can provide insights into microbial adaptation to extreme environments and may lead to the development of novel strategies for enhancing heavy metal resistance in other organisms. In summary, Streptomyces cadmiisoli stands out not only for its ecological role in contaminated environments but also for its potential contributions to biotechnology and medicine, making it a significant organism for further study.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces cadmiisoli

NCBI ID

2184053

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/261/055/GCF_003261055.1_ASM326105v1

File for sequence-based predictions:
GCF_003261055.1_ASM326105v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces cadmiisoli is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While specific clinical implications of Streptomyces cadmiisoli are not extensively documented, its relatives have been associated with various beneficial and pathogenic properties. Antimicrobial resistance is a critical concern, as some Streptomyces species can harbor genes that confer resistance to multiple antibiotics, complicating treatment options for infections. In terms of human health, Streptomyces species are often explored for their potential as probiotics, contributing to gut health and modulating the immune response. They may also play a role in bioremediation, particularly in environments contaminated with heavy metals, such as cadmium, which is relevant given the species name. The pathogenicity of Streptomyces cadmiisoli has not been well characterized, but the genus is known to produce various secondary metabolites that can have toxic effects. Understanding the interactions of Streptomyces cadmiisoli with the human body, particularly in terms of immune evasion strategies, is an area that warrants further research. Overall, while Streptomyces cadmiisoli may not have direct clinical implications documented, its relatives provide a framework for understanding its potential roles in health and disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces cadmiisoli is a species of actinobacteria that is primarily associated with contaminated soils and heavy metal-rich environments. This microorganism thrives in areas where cadmium is prevalent, often found in regions affected by industrial activities, mining, or agricultural runoff. Its ability to tolerate and even utilize cadmium as a nutrient source allows it to occupy a unique ecological niche in these polluted habitats. In these environments, Streptomyces cadmiisoli plays a crucial role in bioremediation, helping to detoxify heavy metals and improve soil health. By breaking down toxic compounds and facilitating the uptake of metals, it contributes to the restoration of ecosystem balance in contaminated areas. This process not only aids in the recovery of the soil but also supports the growth of other microorganisms and plants that may be adversely affected by heavy metal toxicity. Additionally, Streptomyces cadmiisoli exhibits notable interactions with its surroundings, including potential symbiotic relationships with plants. It may enhance plant growth by improving nutrient availability and promoting resistance to metal stress, thus playing a beneficial role in agroecosystems where soil contamination is a concern. Overall, the presence of Streptomyces cadmiisoli in cadmium-contaminated soils highlights its importance in both ecological and environmental contexts, showcasing its adaptability and significance in maintaining soil health and ecosystem functionality.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces cadmiisoli has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. These compounds can be harnessed in fermentation processes to create pharmaceuticals and agricultural products. In the realm of waste management, Streptomyces cadmiisoli has demonstrated capabilities in biodegradation, particularly in the breakdown of heavy metals and organic pollutants in contaminated soils. This makes it a valuable organism for bioremediation efforts, helping to restore environments affected by industrial waste. Furthermore, the organism's enzymatic activity is crucial in biofuel production, where it can be involved in the breakdown of lignocellulosic biomass, facilitating the conversion of plant materials into fermentable sugars. This process is essential for the production of second-generation biofuels, contributing to sustainable energy solutions. Overall, Streptomyces cadmiisoli exemplifies the versatility of actinobacteria in various industries, particularly in pharmaceutical development, waste treatment, and renewable energy sectors, showcasing its importance in modern biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	true	true	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	false	false	true	true	false	true	false	true	false	false	false	false	false	false	false	true	true	false	false	true	true	true	true	true	true	true	true
Host association	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus

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