Yersinia hibernica

General Information

Yersinia hibernica is a recently identified species within the Yersinia genus, which is known for containing several pathogenic species, including Yersinia pestis, the causative agent of plague. What makes Yersinia hibernica particularly interesting is its unique genetic and phenotypic characteristics that distinguish it from other members of the genus. This species was first isolated from a variety of environmental sources, indicating its potential ecological versatility and adaptability. One of the most notable features of Yersinia hibernica is its genetic makeup, which includes several genes that are not found in other Yersinia species. These genes may confer unique metabolic capabilities or environmental resilience, making Yersinia hibernica a valuable subject for studies on microbial adaptation and evolution. Additionally, the presence of unique virulence factors in Yersinia hibernica suggests that it could provide new insights into the mechanisms of pathogenicity within the Yersinia genus. From a research perspective, Yersinia hibernica offers a fascinating opportunity to explore the diversity and evolutionary history of the Yersinia genus. Its distinct genetic profile and environmental adaptability make it a prime candidate for studies on microbial ecology, evolution, and the development of novel antimicrobial strategies. Understanding the unique traits of Yersinia hibernica could also have implications for public health, particularly in understanding how new pathogenic species emerge and adapt to different environments.

Yersinia hibernica is a fascinating bacterium that belongs to the genus Yersinia, which is known for its pathogenic members, including the infamous Yersinia pestis, the causative agent of plague. However, Y. hibernica stands out due to its unique ecological niche and its role in the environment. This organism was first isolated from the intestines of wild rodents in Ireland, indicating its adaptation to a specific host and habitat. Its ability to thrive in colder climates makes it particularly interesting, as it has been associated with the gastrointestinal tracts of animals in temperate regions, suggesting a potential role in the ecology of these environments. One of the most valuable aspects of Y. hibernica is its potential for research in understanding the evolution and adaptation of bacteria to different ecological niches. Studying this organism can provide insights into the genetic and metabolic pathways that allow it to survive in colder temperatures, which may have implications for understanding bacterial resilience in changing climates. Additionally, Y. hibernica has been noted for its low pathogenicity compared to other members of the genus, making it a safer subject for laboratory studies. This characteristic allows researchers to explore its biology without the high biosafety concerns associated with more virulent strains. Furthermore, its presence in wildlife can serve as an indicator of environmental health, making it a potential candidate for ecological monitoring. In summary, Yersinia hibernica is not just another bacterium; it is a key player in understanding microbial ecology, evolution, and the impacts of environmental changes on microbial life. Its unique adaptations and ecological significance make it a valuable organism for ongoing research.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Enterobacterales

Family: Yersiniaceae

Genus: Yersinia

Species: Yersinia hibernica

NCBI ID

2339259

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/004/124/235/GCF_004124235.1_ASM412423v1

File for sequence-based predictions:
GCF_004124235.1_ASM412423v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The bacterium Yersinia hibernica is a member of the Yersinia genus, which includes several species known for their clinical significance. While Y. hibernica is less studied compared to its more notorious relatives, such as Yersinia pestis (the causative agent of plague) and Yersinia enterocolitica (associated with gastrointestinal infections), it has been implicated in certain infections and is of interest in the context of zoonotic diseases. Clinical implications of Y. hibernica include its potential role in gastroenteritis and enteric fevers, particularly in regions where it is endemic. The organism is primarily transmitted through contact with infected animals or consumption of contaminated food, highlighting its relevance in food safety and public health. Furthermore, there is a growing concern regarding antimicrobial resistance among Yersinia species, including Y. hibernica. Resistance to commonly used antibiotics can complicate treatment options for infections caused by this organism. Understanding the mechanisms of immune evasion employed by Y. hibernica is crucial, as it may share similar strategies with other pathogenic Yersinia species, such as the ability to evade phagocytosis and manipulate host immune responses. While there are no widely recognized medical applications of Y. hibernica as a probiotic or therapeutic agent, ongoing research may uncover potential benefits or applications in the future. Overall, the clinical relevance of Y. hibernica underscores the importance of monitoring emerging pathogens and understanding their impact on human health.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Yersinia hibernica is a bacterium that is primarily associated with temperate environments and is often found in the gastrointestinal tracts of mammals, particularly in rodents. This organism thrives in habitats where it can exploit the nutrient-rich conditions provided by its hosts. Its ecological niche is closely linked to the microbiomes of these animals, where it plays a role in the complex interactions of gut flora. Notable interactions include its potential as a pathogen, where it can cause disease in its hosts, leading to significant ecological impacts. In this capacity, _Yersinia hibernica can influence host population dynamics and health, thereby affecting the broader ecosystem. Additionally, it may engage in symbiotic relationships with other gut microorganisms, contributing to the overall balance of the gut microbiome. In terms of environmental adaptation, _Yersinia hibernica has developed mechanisms to survive in the host's digestive system, which is characterized by varying pH levels and the presence of competing microbial species. This adaptability allows it to persist in a niche that is both competitive and dynamic, showcasing its resilience in temperate biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Yersinia hibernica has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to survive in cold environments, which can be harnessed for specific biotechnological processes. For instance, its cold-adapted enzymes can be utilized in enzyme production, making it valuable for industrial processes that require lower temperatures, thus saving energy and reducing costs. In the realm of waste management, Yersinia hibernica has been studied for its role in biodegradation of organic waste. Its metabolic pathways can be leveraged to break down complex organic materials, contributing to more efficient waste treatment processes. This capability is particularly useful in composting and bioremediation efforts, where the breakdown of pollutants is essential. Furthermore, there is ongoing research into the potential of Yersinia hibernica in pharmaceutical development. Its unique biochemical properties may lead to the discovery of novel compounds that could be used in drug formulation or as antimicrobial agents. The organism's ability to produce specific metabolites under certain conditions could be explored for the development of new therapeutic agents. Overall, while Yersinia hibernica is primarily known for its pathogenicity, its industrial applications in biotechnology, waste management, and pharmaceutical development highlight its versatility and potential benefits in various sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	openai/gpt-3.5-turbo-0125	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	google/gemini-pro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	openai/gpt-4o	openai/gpt-4o	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	TRUE	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Biosafety level	N/A	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 1	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 2	biosafety level 1	biosafety level 1	biosafety level 2	biosafety level 2
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	TRUE	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	beta	beta	N/A	N/A	beta	beta	beta	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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