Mycolicibacterium nivoides

General Information

Mycolicibacterium nivoides is a fascinating microorganism belonging to the genus Mycolicibacterium, which is known for its complex and diverse lipid profiles. One of the most intriguing aspects of M. nivoides is its production of mycolic acids, which are long-chain fatty acids that contribute to the unique properties of the cell wall. These mycolic acids are not only crucial for the organism's survival in harsh environments but also make it a subject of interest in the study of bacterial resistance mechanisms. What makes Mycolicibacterium nivoides particularly valuable from a research perspective is its potential role in biodegradation and bioremediation. This organism has shown the ability to degrade various environmental pollutants, including aromatic hydrocarbons, which are common contaminants in soil and water. This capability positions M. nivoides as a promising candidate for use in cleaning up polluted environments, making it a key player in environmental microbiology. Another unique feature of M. nivoides is its slow growth rate, which is characteristic of many mycobacteria. This slow growth can be a double-edged sword; while it poses challenges for laboratory cultivation and study, it also suggests a highly specialized metabolism that could be harnessed for industrial applications, such as the production of bioactive compounds. In addition to its environmental applications, Mycolicibacterium nivoides is of interest in the field of medical microbiology. The genus Mycolicibacterium includes several species that are pathogenic to humans and animals, and studying M. nivoides can provide insights into the pathogenic mechanisms and potential treatments for related diseases. Overall, Mycolicibacterium nivoides stands out due to its unique lipid composition, environmental resilience, and potential applications in bioremediation and medicine. Its study not only enhances our understanding of mycobacterial biology but also opens up new avenues for practical applications in various fields.

Mycolicibacterium nivoides is a fascinating species within the genus Mycolicibacterium, notable for its unique biochemical and ecological characteristics. This organism is particularly interesting due to its ability to thrive in cold environments, which has implications for understanding microbial life in extreme conditions. Its isolation from Arctic and Antarctic regions highlights its potential role in biogeochemical cycles in polar ecosystems. One of the most remarkable features of M. nivoides is its production of mycolic acids, which are long-chain fatty acids that contribute to the organism's cell wall structure. This characteristic is significant as it provides insights into the evolutionary adaptations of bacteria to harsh environments. The presence of mycolic acids also makes M. nivoides a subject of interest in studies related to antibiotic resistance and the development of novel antimicrobial agents. Furthermore, Mycolicibacterium nivoides has been studied for its potential applications in biotechnology, particularly in bioremediation processes. Its ability to degrade complex organic compounds can be harnessed for environmental cleanup efforts, making it a valuable organism in the field of environmental microbiology. Research into this species may lead to advancements in our understanding of microbial ecology and the development of sustainable practices for managing contaminated environments. Overall, M. nivoides stands out not only for its ecological significance but also for its potential contributions to medical and environmental research, making it a compelling subject for further study.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium nivoides

NCBI ID

2487344

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/855/255/GCF_003855255.1_ASM385525v1

File for sequence-based predictions:
GCF_003855255.1_ASM385525v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium nivoides is a member of the genus Mycolicibacterium, which has been associated with various clinical implications, particularly in the context of infections and pathogenicity. This microorganism is known to be a potential opportunistic pathogen, especially in immunocompromised individuals. It has been linked to pulmonary infections and can cause cutaneous infections in some cases. The clinical relevance of M. nivoides is underscored by its ability to evade the immune response, which may involve mechanisms such as the modulation of host cell signaling pathways and the production of biofilms that protect it from phagocytosis. Furthermore, there is growing concern regarding its antimicrobial resistance, as some strains have shown resistance to common antibiotics, complicating treatment options. This resistance is particularly alarming in the context of increasing rates of multidrug-resistant infections globally. In terms of medical applications, while M. nivoides is not widely recognized for therapeutic use like some probiotics, its study contributes to the understanding of mycobacterial infections and the development of potential vaccines or therapeutics targeting similar organisms. Overall, the clinical implications of Mycolicibacterium nivoides highlight the need for continued research into its pathogenic mechanisms and the development of effective treatment strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium nivoides is a species of actinobacteria that is primarily associated with cold environments and polar biomes. This microorganism thrives in glacial habitats and is often found in permafrost regions, where it plays a significant role in the microbial community. Its ability to withstand extreme cold temperatures allows it to occupy ecological niches that are inhospitable to many other organisms. In these polar ecosystems, Mycolicibacterium nivoides contributes to the breakdown of organic matter, facilitating nutrient cycling in the soil. This process is crucial for maintaining the health of the ecosystem, as it helps to release nutrients that are otherwise locked in organic materials. The presence of this bacterium can also influence the biogeochemical cycles of carbon and nitrogen in these cold environments. Additionally, Mycolicibacterium nivoides exhibits notable interactions with other microorganisms, often engaging in symbiotic relationships that enhance its survival and metabolic capabilities. For instance, it may form partnerships with fungi or other bacteria, which can aid in nutrient acquisition or provide protection against environmental stressors. Overall, the ecological role of Mycolicibacterium nivoides in glacial and polar biomes underscores its importance in understanding microbial diversity and ecosystem functioning in extreme environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium nivoides has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where this organism is utilized for its unique metabolic capabilities. It is known to participate in fermentation processes, which can be harnessed for the production of valuable metabolites, including organic acids and alcohols. This makes it a candidate for applications in the food and beverage industry, particularly in the development of fermented products. In the realm of waste management, Mycolicibacterium nivoides has demonstrated the ability to degrade complex organic compounds, making it useful in biodegradation processes. This characteristic is particularly beneficial in the treatment of contaminated environments, such as soil and water, where it can help in the breakdown of pollutants and contribute to bioremediation efforts. Furthermore, the organism's enzymatic activity is of interest in pharmaceutical development. It has been studied for its potential to produce enzymes that can be used in drug synthesis or as biocatalysts in various chemical reactions. This could lead to more sustainable and efficient methods of producing pharmaceuticals. Additionally, there is growing interest in the use of Mycolicibacterium nivoides in biofuel production. Its metabolic pathways may be exploited to convert biomass into biofuels, providing an alternative energy source that is more environmentally friendly compared to fossil fuels. The organism's ability to ferment different substrates could enhance the efficiency of biofuel production processes. Overall, Mycolicibacterium nivoides presents a versatile platform for various industrial applications, particularly in biotechnology, waste management, pharmaceutical development, and biofuel production, showcasing its potential to contribute to sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	google/gemini-pro-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	true	false	false	true	false	true	true	false	false	true	true	true	true	true	true	false	false	false	false	false	false	false	false	true	true	true	true
Biofilm formation	N/A	false	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	true	true	true	true	true	false	true	false	false	false	false	false	false	false	true	true	true	true	false	false	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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