Pandoraea capi

General Information

Pandoraea capi is a fascinating microorganism belonging to the genus Pandoraea. This genus is known for its diverse metabolic capabilities and environmental adaptability. One of the most intriguing aspects of Pandoraea capi is its potential role in bioremediation. Members of the Pandoraea genus have been studied for their ability to degrade a variety of pollutants, including aromatic hydrocarbons and other complex organic compounds. This makes Pandoraea capi particularly valuable for environmental cleanup efforts, especially in contaminated soil and water environments. Another notable feature of Pandoraea capi is its resistance to multiple antibiotics. This characteristic is of significant interest in medical research, as it provides insights into mechanisms of antibiotic resistance and potential strategies for combating multi-drug resistant infections. The genetic basis for this resistance is a subject of ongoing study, with the aim of understanding how these bacteria can survive in the presence of various antimicrobial agents. In addition to its environmental and medical significance, Pandoraea capi also exhibits a unique metabolic versatility. It can utilize a wide range of substrates for growth, which underscores its adaptability to different ecological niches. This metabolic flexibility is not only interesting from a microbiological perspective but also holds potential for industrial applications, such as the production of biofuels and bioplastics. Overall, Pandoraea capi is a microorganism of considerable interest due to its bioremediation potential, antibiotic resistance, and metabolic versatility. These characteristics make it a valuable subject for research in environmental science, medicine, and industrial biotechnology.

Pandoraea capi is a fascinating bacterium that belongs to the genus Pandoraea, which is known for its unique ecological niches and metabolic capabilities. This organism was first isolated from a patient with cystic fibrosis, highlighting its potential role in human health and disease. What makes Pandoraea capi particularly interesting is its ability to degrade complex organic compounds, which positions it as a valuable candidate for bioremediation efforts. Its metabolic versatility allows it to thrive in diverse environments, including soil and aquatic systems, where it can contribute to nutrient cycling and organic matter decomposition. In addition to its ecological significance, Pandoraea capi has garnered attention in the field of microbiology due to its resistance to multiple antibiotics, which raises important questions about treatment options for infections in immunocompromised individuals. This characteristic makes it a subject of study for researchers investigating antibiotic resistance mechanisms and the development of new therapeutic strategies. Furthermore, the genomic analysis of Pandoraea capi has revealed insights into its evolutionary adaptations and potential for horizontal gene transfer, which are critical factors in understanding microbial evolution and ecology. Overall, Pandoraea capi stands out as a unique organism with implications for both environmental science and medical research, making it a valuable focus for ongoing studies.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Betaproteobacteria

Order: Burkholderiales

Family: Burkholderiaceae

Genus: Pandoraea

Species: Pandoraea capi

NCBI ID

2508286

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/902/459/735/GCA_902459735.1_LMG_20602

File for sequence-based predictions:
GCA_902459735.1_LMG_20602_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Pandoraea capi is a gram-negative bacterium that has been increasingly recognized in clinical settings, particularly in patients with cystic fibrosis and other chronic lung diseases. It is known to be associated with pulmonary infections, which can complicate the management of these patients. The presence of Pandoraea capi in respiratory cultures often indicates a more complex microbial community, which can lead to disease exacerbations and increased morbidity. One of the significant clinical implications of Pandoraea capi is its antimicrobial resistance. This organism has shown resistance to multiple classes of antibiotics, making treatment challenging. The mechanisms of resistance include the production of beta-lactamases and other efflux pumps, which can render standard therapies ineffective. This resistance profile necessitates careful selection of antibiotics and may require the use of combination therapies to achieve effective treatment outcomes. In terms of immune evasion, Pandoraea capi can alter its surface structures and produce biofilms, which protect it from both the host immune response and antibiotic treatment. This ability to form biofilms is particularly concerning in the context of chronic infections, as it contributes to persistent infections that are difficult to eradicate. While Pandoraea capi is primarily recognized for its role in pathogenicity, there is ongoing research into its potential applications in biotechnology and probiotics, although these are not yet well-established. Understanding the full clinical implications of Pandoraea capi is crucial for improving patient outcomes, especially in vulnerable populations such as those with compromised respiratory function.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Pandoraea capi is a species of bacteria that is primarily associated with soil environments and plant rhizospheres. This microorganism thrives in nutrient-rich conditions, often found in areas with high organic matter content. Its ecological niche is significant as it plays a role in the decomposition process, contributing to nutrient cycling within the soil ecosystem. In particular, Pandoraea capi has been documented in association with various plants, indicating its potential role in plant-microbe interactions. It may enhance nutrient availability for plants through processes such as nitrogen fixation or phosphate solubilization, thereby promoting plant growth and health. This symbiotic relationship is crucial in agricultural ecosystems, where the presence of beneficial microorganisms can lead to improved crop yields and soil fertility. Additionally, Pandoraea capi has been isolated from contaminated environments, suggesting its adaptability to polluted soils. This adaptability may allow it to contribute to bioremediation efforts, where microorganisms are utilized to degrade environmental pollutants, thus playing a vital role in ecosystem restoration. Overall, Pandoraea capi exemplifies the intricate relationships within terrestrial biomes, highlighting its importance in nutrient cycling, plant health, and environmental remediation.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Pandoraea capi has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its ability to degrade a range of organic compounds, making it a candidate for biodegradation processes in contaminated environments. Its enzymatic activity allows it to break down complex pollutants, which can be harnessed in waste treatment facilities to improve the efficiency of waste processing and reduce environmental impact. In the realm of biofuel production, Pandoraea capi may contribute to the conversion of biomass into biofuels through fermentation processes. By utilizing its metabolic pathways, this microorganism can potentially enhance the yield of bioethanol or biogas from organic materials, thus supporting the shift towards renewable energy sources. Furthermore, there is emerging interest in the pharmaceutical development sector, where Pandoraea capi could be explored for its unique metabolic products. These metabolites may have applications in drug formulation or as bioactive compounds, although more research is needed to fully understand its capabilities in this area. Overall, the versatility of Pandoraea capi in biodegradation, fermentation, and potential pharmaceutical applications highlights its significance in addressing environmental challenges and contributing to sustainable industrial practices.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	anthropic/claude-3-haiku:beta	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	openchat/openchat-7b	mistralai/mistral-7b-instruct	google/gemini-pro	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat
Motility	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain positive ✗	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	N/A	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	true	true	true	false	true	true	false	false	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Biosafety level	biosafety level 1	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Host association	N/A	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	beta	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

Back to Search