Actinomadura rubrisoli

General Information

Actinomadura rubrisoli is a fascinating microorganism that belongs to the genus Actinomadura. This species was first isolated from soil, which is reflected in its name, with 'rubrisoli' indicating its origin from red soil. One of the most intriguing aspects of A. rubrisoli is its potential for producing novel bioactive compounds. Members of the genus Actinomadura are well-known for their ability to synthesize a variety of secondary metabolites, including antibiotics, antifungals, and anticancer agents. This makes A. rubrisoli particularly valuable for pharmaceutical research and biotechnology applications. Another unique characteristic of A. rubrisoli is its complex life cycle, which includes the formation of filamentous structures. These structures can differentiate into spores under certain conditions, contributing to the organism's resilience and adaptability in diverse environments. The ability to form such intricate structures is not only interesting from a microbiological perspective but also offers insights into the evolutionary strategies of soil-dwelling bacteria. Furthermore, A. rubrisoli exhibits a distinctive pigmentation, often producing reddish or orange hues, which can be attributed to the production of specific pigments. These pigments may have protective roles against environmental stressors such as UV radiation and oxidative damage, adding another layer of interest to the study of this microorganism. In summary, Actinomadura rubrisoli is a microorganism of significant interest due to its potential for producing novel bioactive compounds, its complex life cycle involving filamentous growth, and its distinctive pigmentation. These characteristics make it a valuable subject for ongoing research in microbiology, biotechnology, and pharmaceutical sciences.

Actinomadura rubrisoli is a fascinating actinobacterium that was first isolated from soil samples in a red soil environment. This organism is particularly interesting due to its ability to produce a variety of bioactive compounds, which have significant implications in the field of natural product research. One of the most notable features of A. rubrisoli is its potential for antibiotic production, making it a valuable candidate for the discovery of new antimicrobial agents. Researchers are particularly keen on exploring its secondary metabolites, which may exhibit unique properties that could lead to the development of novel pharmaceuticals. Additionally, A. rubrisoli has been studied for its role in soil ecology, contributing to nutrient cycling and organic matter decomposition. Its ability to thrive in specific soil conditions highlights its adaptability and ecological significance. The organism's genetic makeup has also been a subject of interest, as it may provide insights into the biosynthetic pathways responsible for its diverse metabolite production. This makes Actinomadura rubrisoli not only a subject of microbiological interest but also a potential resource for biotechnological applications in agriculture and medicine.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Streptosporangiales

Family: Thermomonosporaceae

Genus: Actinomadura

Species: Actinomadura rubrisoli

NCBI ID

2530368

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/004/349/215/GCF_004349215.1_ASM434921v1

File for sequence-based predictions:
GCF_004349215.1_ASM434921v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Actinomadura rubrisoli is a member of the Actinobacteria phylum and has been studied for its potential clinical implications. It is primarily known for its role in the production of antibiotics, particularly in the context of soil microbiology. This organism has been isolated from various soil environments, indicating its ecological significance and potential for biotechnological applications. In terms of human health, Actinomadura rubrisoli has been associated with certain infections, although it is not commonly recognized as a primary pathogen. There have been rare cases of opportunistic infections in immunocompromised individuals, highlighting the need for awareness of this organism in clinical settings. One of the notable aspects of Actinomadura rubrisoli is its potential for antimicrobial resistance. While specific resistance mechanisms have not been extensively documented, the genus Actinomadura is known for producing various bioactive compounds, which may contribute to the development of resistance in other microorganisms. This underscores the importance of monitoring such organisms in the context of antibiotic stewardship. Furthermore, the metabolic products of Actinomadura rubrisoli may have applications in therapeutics, particularly in the development of new antibiotics or as a source of bioactive compounds. Research into its secondary metabolites could lead to novel treatments for bacterial infections, especially in an era of increasing antimicrobial resistance. Overall, while Actinomadura rubrisoli is not a major pathogen, its role in antibiotic production, potential for opportunistic infections, and contributions to antimicrobial resistance make it a relevant organism in the fields of microbiology and clinical medicine.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Actinomadura rubrisoli is a filamentous bacterium commonly found in soil ecosystems, particularly in agricultural soils and forest floors. This microorganism thrives in environments rich in organic matter, where it plays a crucial role in the decomposition of complex organic compounds. Its ability to degrade various substrates makes it an important player in nutrient cycling within these biomes. In agricultural soils, Actinomadura rubrisoli contributes to soil health by promoting the breakdown of organic residues, thus enhancing soil fertility. It is often associated with the rhizosphere of plants, where it can engage in mutualistic relationships with plant roots, aiding in nutrient uptake and promoting plant growth. In forest ecosystems, this bacterium is found in the litter layer and upper soil horizons, where it interacts with other microorganisms, such as fungi, in a complex web of microbial communities. These interactions are vital for maintaining the balance of the ecosystem, as they facilitate the decomposition process and the recycling of nutrients. Furthermore, Actinomadura rubrisoli exhibits remarkable environmental adaptability, allowing it to thrive in varying conditions, including changes in moisture and temperature. Its resilience and functional diversity make it a key organism in maintaining the health and stability of the biomes it inhabits.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Actinomadura rubrisoli has shown significant potential in various industrial applications. One of the primary areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly noted for its role in fermentation, which is a critical process in the production of pharmaceuticals and other bioactive substances. In the realm of waste management, Actinomadura rubrisoli has demonstrated capabilities in biodegradation, effectively breaking down complex organic materials and pollutants in soil and water. This makes it a valuable asset in bioremediation efforts, where it can help restore contaminated environments. Furthermore, the organism is being explored for its potential in biofuel production. Its metabolic pathways can be harnessed to convert biomass into biofuels through fermentation processes, contributing to sustainable energy solutions. In summary, Actinomadura rubrisoli is a versatile microorganism with applications spanning pharmaceutical development, waste treatment, and biofuel production, showcasing its importance in modern industrial biotechnology.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	google/gemma-7b-it	google/gemma-7b-it	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	false	true	true	true	false	true	true	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	false	true	true	true	true	true	true	false	false	false	false	false	false	true	true	false	false	false	false	true	true	false	false	true	true	false	false
Host association	N/A	false	false	false	true	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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