Streptomyces aquilus

General Information

Streptomyces aquilus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most intriguing aspects of S. aquilus is its potential for producing novel antibiotics and other bioactive compounds. This makes it a valuable subject for pharmaceutical research and biotechnology. Streptomyces species are well-known for their complex life cycle, which includes the formation of a mycelium and spore chains, contributing to their ability to thrive in diverse environments. The genus Streptomyces is responsible for the production of over two-thirds of the clinically useful antibiotics of natural origin, including well-known drugs like streptomycin, neomycin, and chloramphenicol. Streptomyces aquilus specifically has been isolated from unique environments, which often harbor microorganisms with distinctive metabolic capabilities. This species' ability to produce a wide array of enzymes and secondary metabolites makes it a subject of interest for biotechnological applications, including the degradation of complex organic materials and the synthesis of industrially relevant compounds. In addition to its biotechnological potential, S. aquilus contributes to our understanding of microbial ecology and the evolutionary pathways that lead to the diversification of metabolic functions in bacteria. Its genetic and metabolic versatility underscores the importance of Streptomyces species in natural product discovery and environmental sustainability. Overall, Streptomyces aquilus represents a promising avenue for future research aimed at discovering new drugs, understanding microbial interactions, and harnessing microbial processes for industrial applications.

Streptomyces aquilus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, which makes it a subject of interest in pharmaceutical research. This species is part of the larger genus Streptomyces, which is renowned for its prolific secondary metabolite production, including antibiotics, antifungals, and anticancer agents. What sets S. aquilus apart is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic applications. One of the most intriguing aspects of S. aquilus is its ecological role in soil environments, where it contributes to the degradation of complex organic materials. This ability not only aids in nutrient cycling but also highlights its potential in bioremediation efforts, particularly in the breakdown of pollutants. The organism's capacity to thrive in diverse environmental conditions further enhances its value for biotechnological applications. Additionally, research into S. aquilus has revealed insights into its genetic makeup, which can provide a better understanding of the biosynthetic gene clusters responsible for its secondary metabolite production. This knowledge is crucial for the development of novel drugs and can lead to the discovery of new compounds that may not be produced under standard laboratory conditions. Overall, Streptomyces aquilus represents a promising avenue for exploration in the fields of microbiology, pharmacology, and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces aquilus

NCBI ID

2548456

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/003/955/715/GCF_003955715.1_ASM395571v1

File for sequence-based predictions:
GCF_003955715.1_ASM395571v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces aquilus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. aquilus itself is not commonly associated with human disease, its relatives have been implicated in various infections and have notable clinical relevance due to their antibiotic-producing capabilities. Antimicrobial resistance is a critical concern in the context of Streptomyces species, as they can harbor genes that confer resistance to multiple classes of antibiotics, complicating treatment options for bacterial infections. In terms of immune evasion, S. aquilus and related species may produce secondary metabolites that can modulate host immune responses, although specific mechanisms for S. aquilus are not well-documented. The potential for this organism to be involved in opportunistic infections in immunocompromised patients has been suggested, but further research is needed to clarify its pathogenic potential. Additionally, the use of Streptomyces species in biotechnology for the development of therapeutics and probiotics highlights their importance in medical applications. The ability of S. aquilus to produce various bioactive compounds may offer avenues for novel drug development, particularly in the fight against antibiotic-resistant pathogens. Overall, while S. aquilus may not be a primary pathogen, its role in antibiotic production and potential implications in infections and resistance mechanisms make it a noteworthy organism in clinical microbiology.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces aquilus is a species of actinobacteria commonly found in soil and freshwater environments. This microorganism thrives in nutrient-rich substrates, often associated with decaying organic matter, which provides an ideal habitat for its growth and metabolic activities. The ecological niche of S. aquilus is characterized by its ability to decompose complex organic compounds, playing a crucial role in nutrient cycling within the ecosystem. Soil Biomes: In terrestrial ecosystems, S. aquilus contributes significantly to the soil microbiome, where it engages in the breakdown of organic materials, thus enhancing soil fertility. Its presence is vital for the formation of humus and the release of essential nutrients, which supports plant growth. Additionally, S. aquilus can exhibit antibiotic production, which helps in suppressing pathogenic microorganisms, thereby promoting a healthier soil environment. Freshwater Biomes: In freshwater habitats, S. aquilus can be found in sediments and biofilms, where it interacts with other microbial communities. This organism is known for its ability to degrade pollutants, including various organic compounds, making it an important player in bioremediation processes. Its metabolic versatility allows it to adapt to varying environmental conditions, such as changes in nutrient availability and pH levels. Overall, Streptomyces aquilus exemplifies the intricate relationships within its biomes, showcasing its role in decomposition, nutrient cycling, and bioremediation, while also highlighting its potential for symbiotic interactions with plants and other microorganisms in its environment.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces aquilus has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where Streptomyces aquilus is utilized for its ability to produce a range of bioactive compounds, including antibiotics and enzymes. This organism is particularly known for its role in fermentation, which is a critical process in the production of these valuable metabolites. In the realm of waste management, Streptomyces aquilus has demonstrated capabilities in biodegradation, particularly in the breakdown of complex organic materials. This makes it a candidate for use in bioremediation efforts, where it can help in the detoxification of contaminated environments, such as soil and water. Furthermore, the enzymatic activity of Streptomyces aquilus is of great interest in pharmaceutical development. The enzymes produced by this microorganism can be harnessed for various applications, including the synthesis of pharmaceutical intermediates and the enhancement of drug formulations. Overall, Streptomyces aquilus represents a versatile organism with applications spanning biofuel production, where its metabolic pathways can be exploited for the conversion of biomass into renewable energy sources, and agriculture, where its antimicrobial properties can be used to develop natural pesticides. The diverse capabilities of Streptomyces aquilus make it a valuable asset in multiple industries, particularly in processes involving fermentation, biodegradation, and enzyme production.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-flash-1.5	anthropic/claude-3.5-sonnet	meta-llama/llama-3-8b-instruct:nitro	google/gemini-pro	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerotolerant ✗	aerobic ✓	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	false	false	true	true	true	false	false	false	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Host association	FALSE	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Plant pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	spirillum ✗	spirillum ✗	bacillus ✗	bacillus ✗

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