Klebsiella pasteurii

General Information

Klebsiella pasteurii is a fascinating microorganism that has garnered attention due to its unique metabolic capabilities and potential applications in biotechnology. One of the most noteworthy characteristics of K. pasteurii is its ability to precipitate calcium carbonate through a process known as microbial-induced calcite precipitation (MICP). This ability makes it a valuable candidate for applications in biocementation and bioremediation, where it can be used to strengthen soil or repair concrete structures. Another interesting aspect of K. pasteurii is its role in the nitrogen cycle. It is capable of fixing nitrogen, which means it can convert atmospheric nitrogen into a form that is usable by plants. This trait is particularly valuable in agricultural settings, where it can be used to enhance soil fertility and reduce the need for chemical fertilizers. From a research perspective, K. pasteurii is also studied for its potential in the field of synthetic biology. Scientists are exploring ways to harness its metabolic pathways for the production of biofuels and other valuable chemicals. The organism's genetic makeup and regulatory mechanisms are subjects of ongoing research, aiming to understand and manipulate its capabilities for various industrial applications. In summary, Klebsiella pasteurii stands out due to its calcium carbonate precipitation, nitrogen fixation, and potential applications in biocementation, bioremediation, and synthetic biology. These unique traits make it a microorganism of significant interest in both environmental and industrial biotechnology.

Klebsiella pasteurii is a fascinating bacterium known for its unique ability to precipitate calcium carbonate, a process that has garnered significant interest in both environmental and industrial applications. This organism is particularly notable for its role in biogeochemical cycles, where it contributes to the natural formation of limestone and other carbonate minerals. The ability to induce mineralization makes K. pasteurii a valuable organism in the field of bioremediation, where it can be utilized to stabilize soils and reduce heavy metal contamination through the formation of insoluble precipitates. In addition to its environmental significance, K. pasteurii has been studied for its potential in bioengineering applications, particularly in the development of self-healing concrete. The incorporation of this bacterium into concrete mixtures can lead to the precipitation of calcium carbonate within cracks, effectively sealing them and enhancing the durability of structures. This innovative approach not only extends the lifespan of concrete but also reduces maintenance costs and resource consumption. Furthermore, K. pasteurii is of interest in the study of microbial ecology due to its interactions with other microorganisms and its adaptability to various environmental conditions. Its metabolic pathways and genetic makeup are subjects of ongoing research, providing insights into microbial diversity and the evolutionary strategies employed by bacteria in response to environmental stresses. Overall, Klebsiella pasteurii stands out as a remarkable organism with significant implications for environmental science, engineering, and microbial ecology.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Enterobacterales

Family: Enterobacteriaceae

Genus: Klebsiella

Species: Klebsiella pasteurii

NCBI ID

2587529

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/018/139/045/GCA_018139045.1_ASM1813904v1

File for sequence-based predictions:
GCA_018139045.1_ASM1813904v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Klebsiella pasteurii is a member of the Enterobacteriaceae family and is primarily known for its role in the nitrogen cycle, particularly in soil environments. However, its clinical implications are becoming increasingly relevant due to its potential pathogenicity. While K. pasteurii is not as widely recognized as other Klebsiella species, it has been associated with infections in immunocompromised patients, particularly in cases of urinary tract infections and respiratory infections. Pathogenicity may be attributed to its ability to produce biofilms, which can enhance its survival in hostile environments and contribute to chronic infections. In terms of antimicrobial resistance, there is a growing concern regarding the resistance mechanisms exhibited by various Klebsiella species, including the production of extended-spectrum beta-lactamases (ESBLs). Although specific data on K. pasteurii is limited, the potential for resistance to commonly used antibiotics poses a significant challenge in clinical settings. Furthermore, the organism's interaction with the human body may involve immune evasion strategies, such as the production of polysaccharide capsules that can inhibit phagocytosis by immune cells. This characteristic is shared with other pathogenic Klebsiella species, which complicates treatment options and increases the risk of nosocomial infections. While K. pasteurii is not commonly used in medical applications, its relatives in the Klebsiella genus have been explored for their potential as probiotics and in the development of vaccines. Continued research into the clinical relevance of K. pasteurii is necessary to fully understand its implications in human health and disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Klebsiella pasteurii is a notable bacterium primarily associated with soil environments and aquatic habitats. This microorganism thrives in nutrient-rich conditions, often found in agricultural soils where it plays a significant role in the nitrogen cycle. Its ability to fix nitrogen makes it an essential contributor to soil fertility, enhancing plant growth and supporting agricultural productivity. In addition to its presence in soils, Klebsiella pasteurii is also found in freshwater ecosystems, where it can inhabit sediments and interact with various organic materials. Here, it participates in the decomposition of organic matter, contributing to nutrient cycling and energy flow within the ecosystem. Notably, this bacterium exhibits a symbiotic relationship with certain plants, aiding in nutrient uptake and enhancing plant resilience against environmental stressors. Its adaptability to varying environmental conditions, including fluctuations in moisture and nutrient availability, underscores its ecological significance. Overall, Klebsiella pasteurii is a vital microorganism within its biomes, influencing both soil health and aquatic ecosystems through its roles in nutrient cycling and symbiotic interactions.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Klebsiella pasteurii has shown significant potential in various industrial applications, particularly in the fields of biotechnology, waste management, and biofuel production. One of the most notable uses of Klebsiella pasteurii is in the process of biodegradation, where it can effectively break down complex organic materials, making it valuable for waste treatment facilities. This capability allows for the conversion of waste into less harmful substances, thereby contributing to environmental sustainability. In the realm of biofuel production, Klebsiella pasteurii is involved in fermentation processes that can convert biomass into bioethanol. This microorganism can utilize various substrates, including agricultural waste, to produce ethanol, which serves as a renewable energy source. The efficiency of Klebsiella pasteurii in fermentative pathways makes it a candidate for enhancing biofuel yields. Additionally, Klebsiella pasteurii has been studied for its role in pharmaceutical development, particularly in the production of enzymes that can be used in drug synthesis. The enzymatic activity of this organism can facilitate the breakdown of complex compounds, leading to the development of new pharmaceuticals. Overall, the diverse applications of Klebsiella pasteurii in biodegradation, fermentation, and enzyme production highlight its importance in advancing sustainable practices across multiple industries.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	meta-llama/llama-3-70b-instruct:nitro	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	openchat/openchat-7b	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro
Motility	FALSE	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true
Animal pathogenicity	TRUE	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓
Biosafety level	biosafety level 2	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	N/A	false	false	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false	false	false	false	false
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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