Microbacterium algeriense

General Information

Microbacterium algeriense is a fascinating microorganism that has garnered attention due to its unique characteristics and potential applications. This bacterium was first isolated from an Algerian soil sample, which highlights its adaptability to diverse environmental conditions. One of the most intriguing aspects of M. algeriense is its ability to produce a variety of bioactive compounds, making it a subject of interest for pharmaceutical and biotechnological research. Notably, Microbacterium algeriense has shown potential in the biodegradation of pollutants, which underscores its value in environmental bioremediation efforts. Its enzymatic repertoire includes enzymes capable of breaking down complex organic compounds, suggesting that it could play a significant role in the detoxification of contaminated environments. Additionally, the genomic analysis of M. algeriense has revealed a wealth of genetic information that could be harnessed for the development of novel antibiotics and other therapeutic agents. The bacterium's ability to thrive in nutrient-poor conditions also makes it an excellent model organism for studying microbial survival strategies and metabolic versatility. In summary, Microbacterium algeriense stands out due to its bioactive compound production, biodegradation capabilities, and genomic potential, making it a valuable organism for both environmental and medical research.

Microbacterium algeriense is a fascinating species of bacteria that belongs to the genus Microbacterium, which is known for its diverse ecological roles and adaptability. This organism was first isolated from a soil sample in Algeria, highlighting its potential significance in understanding microbial diversity in arid environments. One of the most interesting aspects of M. algeriense is its ability to thrive in extreme conditions, which makes it a valuable subject for research in extremophiles and their applications in biotechnology. The metabolic versatility of M. algeriense allows it to utilize a variety of organic compounds, which is particularly intriguing for studies focused on bioremediation. This capability suggests that M. algeriense could play a role in the degradation of pollutants, making it a candidate for environmental cleanup efforts. Furthermore, its unique enzymatic pathways may provide insights into novel biocatalysts that can be harnessed for industrial processes. In addition to its ecological importance, M. algeriense has been studied for its potential in producing bioactive compounds. Research has indicated that this species may synthesize antimicrobial substances, which could lead to the development of new antibiotics in an era where antibiotic resistance is a growing concern. The exploration of its genomic and metabolic pathways could unveil further applications in medicine and agriculture. Overall, Microbacterium algeriense stands out not only for its resilience in harsh environments but also for its promising applications in bioremediation and biotechnology, making it a valuable organism for ongoing research and exploration.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micrococcales

Family: Microbacteriaceae

Genus: Microbacterium

Species: Microbacterium algeriense

NCBI ID

2615184

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/027/678/825/GCF_027678825.1_ASM2767882v1

File for sequence-based predictions:
GCF_027678825.1_ASM2767882v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Microbacterium algeriense is a member of the genus Microbacterium, which is known for its environmental presence and potential clinical significance. While M. algeriense is not as widely studied as some other pathogens, it has been isolated from various clinical specimens, indicating its potential role in infections in humans. Clinical implications of M. algeriense include its association with opportunistic infections, particularly in immunocompromised patients. The organism has been reported in cases of bacteremia and wound infections, highlighting its pathogenic potential in vulnerable populations. In terms of antimicrobial resistance, there is limited data available, but like many members of the Microbacterium genus, M. algeriense may exhibit resistance to certain antibiotics, which complicates treatment options. This underscores the importance of susceptibility testing in clinical settings. Furthermore, the organism's ability to evade the immune response is an area of interest, as it may possess mechanisms that allow it to persist in the host despite an active immune system. Understanding these mechanisms is crucial for developing effective therapeutic strategies. While Microbacterium algeriense is not commonly associated with outbreaks, its presence in clinical samples suggests that it should be considered in differential diagnoses, especially in cases of unexplained infections in patients with underlying health conditions. Overall, further research is needed to fully elucidate the clinical relevance and pathogenicity of M. algeriense.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Microbacterium algeriense is a species of bacteria that is primarily associated with soil environments and plant-associated habitats. This microorganism thrives in arid and semi-arid regions, where it plays a crucial role in nutrient cycling and soil health. Its ability to degrade organic matter contributes to the soil organic carbon pool, enhancing soil fertility and structure. In these terrestrial biomes, M. algeriense often interacts with various plant species, establishing a symbiotic relationship that can promote plant growth. This interaction is particularly significant in desert ecosystems, where water availability is limited, and nutrient uptake is critical for plant survival. Furthermore, Microbacterium algeriense has been documented in rhizosphere environments, where it can influence plant health by suppressing pathogenic organisms and enhancing nutrient availability. Its presence in these habitats underscores its role as a beneficial microorganism in promoting plant resilience against environmental stressors. Overall, M. algeriense exemplifies the intricate relationships within soil ecosystems, highlighting its importance in maintaining ecological balance and supporting plant life in challenging environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Microbacterium algeriense has shown potential in various industrial applications, particularly in the fields of biotechnology, waste management, and pharmaceutical development. This organism is known for its ability to thrive in extreme environments, which makes it a candidate for biodegradation processes, particularly in the breakdown of complex organic compounds found in waste materials. In the realm of biotechnology, Microbacterium algeriense can be utilized in fermentation processes to produce valuable metabolites. Its enzymatic activity is noteworthy, as it can produce enzymes that facilitate the degradation of pollutants, thus playing a crucial role in bioremediation efforts. This is particularly relevant in the treatment of contaminated soils and water, where the organism can help in the detoxification of hazardous substances. Moreover, in pharmaceutical development, the unique metabolic pathways of Microbacterium algeriense may lead to the discovery of novel compounds with antimicrobial properties. The organism's ability to synthesize bioactive molecules can be harnessed for the development of new drugs, contributing to the pharmaceutical industry. Overall, Microbacterium algeriense presents a promising avenue for innovation in waste management, biofuel production, and pharmaceutical research, making it a valuable microorganism in various industrial sectors.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	google/gemini-pro-1.5	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	anthropic/claude-3-haiku:beta	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct
Motility	FALSE	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain positive ✓	gram stain variable ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	N/A	aerobic ✓	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	false	false	false	false	false	true	false	false	false	false	true	true	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false
Biofilm formation	N/A	false	true	true	true	true	true	true	false	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	false	false	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	false	false	false	false	false	false	false	false	false	true	true	true	true	true	true	true	true	false	false	false	false
Host association	FALSE	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	coccus ✗	coccus ✗

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