Bacteroides zhangwenhongii

General Information

Bacteroides zhangwenhongii is a recently identified species within the genus Bacteroides, which is known for its significant role in the human gut microbiome. This microorganism is particularly interesting due to its potential implications in human health and disease. One of the most notable characteristics of Bacteroides zhangwenhongii is its ability to break down complex carbohydrates, which is crucial for maintaining gut health and providing energy to the host. The species was named in honor of Dr. Zhang Wenhong, a prominent Chinese infectious disease expert, highlighting its importance in the scientific community. Bacteroides zhangwenhongii contributes to the balance of the gut microbiota and has been studied for its interactions with other microbial species in the gut. Research into Bacteroides zhangwenhongii has shown that it may play a role in modulating the immune system, potentially influencing inflammatory responses and protecting against certain gastrointestinal diseases. This makes it a valuable subject for further studies aimed at understanding the complex dynamics of the gut ecosystem and its impact on overall health. Additionally, the genome of Bacteroides zhangwenhongii has been sequenced, providing insights into its metabolic pathways and potential for biotechnological applications. The genetic information reveals a variety of enzymes and metabolic capabilities that could be harnessed for industrial processes, such as the production of biofuels or bioremediation. In summary, Bacteroides zhangwenhongii is a fascinating microorganism with significant implications for human health, scientific research, and potential biotechnological applications. Its ability to interact with the human host and other microbes in the gut makes it a key player in the study of the microbiome and its effects on health and disease.

Bacteroides zhangwenhongii is a fascinating species of bacteria that belongs to the genus Bacteroides, which is known for its significant role in the human gut microbiome. This organism is particularly interesting due to its ability to degrade complex polysaccharides, which contributes to the fermentation processes in the intestines. This capability not only aids in nutrient absorption but also plays a crucial role in maintaining gut health. One of the unique aspects of Bacteroides zhangwenhongii is its potential to produce short-chain fatty acids (SCFAs) during fermentation. SCFAs, such as butyrate, are vital for colon health and have been linked to anti-inflammatory effects and the regulation of immune responses. The production of SCFAs by this species highlights its importance in metabolic health and its potential therapeutic applications in conditions like obesity and inflammatory bowel disease. Additionally, Bacteroides zhangwenhongii has been studied for its interactions with other gut microbiota, which can influence the overall microbial community structure. Understanding these interactions is essential for developing probiotics and prebiotics aimed at enhancing gut health. Furthermore, this species has garnered attention in research related to antibiotic resistance, as many members of the Bacteroides genus are known to harbor resistance genes. Investigating Bacteroides zhangwenhongii can provide insights into the mechanisms of resistance and the implications for clinical treatments. Overall, Bacteroides zhangwenhongii represents a valuable subject for research in microbiology, nutrition, and health sciences.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacteroidota

Class: Bacteroidia

Order: Bacteroidales

Family: Bacteroidaceae

Genus: Bacteroides

Species: Bacteroides zhangwenhongii

NCBI ID

2650157

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/009/193/325/GCF_009193325.2_ASM919332v2

File for sequence-based predictions:
GCF_009193325.2_ASM919332v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Bacteroides zhangwenhongii is a member of the Bacteroides genus, which is known for its role in the human gut microbiome. This species has been associated with various clinical implications, particularly in the context of infections and immune response modulation. Bacteroides species, including B. zhangwenhongii, are typically commensal organisms that contribute to gut health by aiding in the digestion of complex carbohydrates and maintaining a balanced microbiota. However, they can also become opportunistic pathogens, especially in immunocompromised individuals or those with disrupted gut flora. Infections caused by B. zhangwenhongii may include abscesses, peritonitis, and other intra-abdominal infections, often following surgical procedures or trauma. The pathogenicity of B. zhangwenhongii is linked to its ability to evade the immune response through various mechanisms, such as the production of polysaccharide capsules that inhibit phagocytosis and the secretion of enzymes that degrade host tissues. Furthermore, this organism is known to exhibit antimicrobial resistance, particularly to beta-lactam antibiotics, which poses challenges in treatment options for infections. In terms of medical applications, while Bacteroides zhangwenhongii itself has not been specifically highlighted for therapeutic use, its relatives in the Bacteroides genus are being studied for potential use as probiotics to restore gut health and prevent dysbiosis. Overall, understanding the clinical implications of Bacteroides zhangwenhongii is crucial for managing its role in human health and disease.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Bacteroides zhangwenhongii is a species of bacteria that primarily inhabits the human gastrointestinal tract. This organism plays a crucial role in the complex microbial ecosystem of the gut, contributing to the breakdown of complex carbohydrates and the fermentation of dietary fibers. Its presence is essential for maintaining a balanced gut microbiome, which is vital for overall health and digestion. Ecological Niches: Within the gut, Bacteroides zhangwenhongii occupies a specific niche where it interacts with other microbial species. It is known to engage in mutualistic relationships with the host, aiding in nutrient absorption and the synthesis of essential vitamins. This bacterium can also influence the immune system, helping to modulate inflammatory responses and protect against pathogenic bacteria. Habitats: The primary habitat for Bacteroides zhangwenhongii is the large intestine, where it thrives in an anaerobic environment. This bacterium is adapted to the low-oxygen conditions of the gut, utilizing fermentation pathways to metabolize substrates that are otherwise indigestible by human enzymes. Environmental Adaptation: Bacteroides zhangwenhongii exhibits remarkable adaptability to varying dietary conditions, which allows it to flourish in diverse dietary environments. Its ability to degrade polysaccharides from plant materials makes it particularly important in diets rich in fiber. Additionally, it can respond to changes in the gut environment, such as pH fluctuations and the presence of other microbial species, ensuring its survival and functionality within the gut ecosystem. In summary, Bacteroides zhangwenhongii is a vital component of the gut microbiome, playing significant roles in digestion, nutrient absorption, and immune modulation, while thriving in the unique anaerobic conditions of the large intestine.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Bacteroides zhangwenhongii has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its role in biodegradation, where it can effectively break down complex organic materials, making it valuable in the treatment of organic waste. Its enzymatic activity allows it to degrade polysaccharides and other macromolecules, which can be harnessed in waste treatment processes to enhance the efficiency of waste decomposition and reduce environmental impact. In the realm of biofuel production, Bacteroides zhangwenhongii may contribute to the conversion of biomass into fermentable sugars, which can subsequently be fermented into biofuels. This process involves fermentation, where the organism can utilize various substrates, potentially leading to the production of ethanol or other biofuels, thus supporting sustainable energy initiatives. Additionally, there is growing interest in the pharmaceutical development sector, where Bacteroides zhangwenhongii could be explored for its ability to produce bioactive compounds. These compounds may have therapeutic properties, making the organism a candidate for further research in drug discovery and development. Overall, the applications of Bacteroides zhangwenhongii in biodegradation, biofuel production, and pharmaceutical development highlight its significance in advancing industrial processes and promoting environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	anthropic/claude-3.5-sonnet	anthropic/claude-3.5-sonnet	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	perplexity/llama-3-sonar-small-32k-chat	perplexity/llama-3-sonar-small-32k-chat
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	anaerobic	anaerobic ✓	anaerobic ✓	N/A	anaerobic ✓	anaerobic ✓	N/A	N/A	N/A	N/A	N/A	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	anaerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	true	true	false	true	true	false	false	true	false	false	false	false	false	false	true	true	true	true	true	true	false	false	true	true
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Host association	N/A	false	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

Back to Search