Streptomyces phaeolivaceus

General Information

Streptomyces phaeolivaceus is a fascinating microorganism belonging to the genus Streptomyces, which is renowned for its prolific production of secondary metabolites. One of the most notable characteristics of S. phaeolivaceus is its ability to produce a wide array of bioactive compounds, including antibiotics, antifungals, and antitumor agents. This makes it a valuable organism in pharmaceutical research and biotechnology. The genus Streptomyces is well-known for its complex life cycle and filamentous growth, which resembles that of fungi. S. phaeolivaceus forms branching mycelia and produces spores, contributing to its resilience and adaptability in various environments. Another intriguing aspect of S. phaeolivaceus is its pigmentation. The species name 'phaeolivaceus' hints at its characteristic brownish-olive coloration, which is due to the production of specific pigments. These pigments not only serve as a distinguishing feature but may also have potential applications in dye and pigment industries. From a genetic perspective, S. phaeolivaceus possesses a large and complex genome, typical of the Streptomyces genus. This genetic richness underpins its ability to synthesize diverse secondary metabolites and adapt to different ecological niches. Researchers are particularly interested in the genetic pathways and regulatory mechanisms that control the production of these bioactive compounds, as understanding these processes can lead to the discovery of new drugs and therapeutic agents. In summary, Streptomyces phaeolivaceus is a microorganism of significant interest due to its prolific production of bioactive compounds, unique pigmentation, and complex genetic makeup. Its contributions to natural product discovery and potential industrial applications make it a valuable subject of study in microbiology and biotechnology.

Streptomyces phaeolivaceus is a fascinating actinobacterium known for its remarkable ability to produce a variety of bioactive compounds, including antibiotics and antifungal agents. This organism is part of the larger genus Streptomyces, which is renowned for its prolific secondary metabolite production, making it a valuable resource in pharmaceutical research and development. One of the most interesting aspects of S. phaeolivaceus is its unique metabolic pathways that allow it to synthesize compounds with potential therapeutic applications. For instance, it has been studied for its ability to produce phaeolivacin, a compound that exhibits significant antimicrobial activity against various pathogens. This characteristic not only highlights its potential in drug discovery but also underscores the ecological role it plays in its natural habitat, where it competes with other microorganisms. Additionally, S. phaeolivaceus is notable for its adaptability to different environmental conditions, which can influence its metabolic output. This adaptability makes it an intriguing subject for studies on microbial ecology and evolution, as researchers seek to understand how environmental factors can shape the biosynthetic capabilities of such organisms. Furthermore, the genomic analysis of S. phaeolivaceus has revealed insights into its genetic makeup, providing a deeper understanding of the biosynthetic gene clusters responsible for its secondary metabolite production. This information is invaluable for biotechnological applications, where scientists aim to harness these pathways for the production of novel compounds. In summary, Streptomyces phaeolivaceus stands out due to its antibiotic-producing capabilities, genetic diversity, and ecological significance, making it a key player in the ongoing search for new antimicrobial agents and a model organism for studying microbial metabolism and genetics.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Kitasatosporales

Family: Streptomycetaceae

Genus: Streptomyces

Species: Streptomyces phaeolivaceus

NCBI ID

2653200

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCF/009/184/865/GCF_009184865.1_ASM918486v1

File for sequence-based predictions:
GCF_009184865.1_ASM918486v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Streptomyces phaeolivaceus is a member of the genus Streptomyces, which is known for its significant role in the production of antibiotics and other bioactive compounds. While S. phaeolivaceus itself is not commonly associated with human infections, its relatives have been implicated in various infections and can exhibit pathogenicity under certain conditions. This organism is primarily recognized for its ability to produce antimicrobial agents, which have potential applications in treating bacterial infections. In terms of immune response, S. phaeolivaceus may interact with the human microbiome, contributing to a balanced microbial community that can enhance host defenses against pathogens. However, the specific mechanisms of immune evasion or modulation by this species are not well-documented. Moreover, the potential for antimicrobial resistance is a concern, as some Streptomyces species have been found to harbor resistance genes that could be transferred to pathogenic bacteria. This highlights the importance of monitoring such organisms in clinical and environmental settings. In summary, while Streptomyces phaeolivaceus is not directly linked to specific diseases, its role in antibiotic production and its interactions within the human microbiome underscore its relevance in the context of human health and disease management.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Streptomyces phaeolivaceus is a species of actinobacteria commonly found in soil ecosystems and decaying organic matter. This microorganism thrives in environments rich in organic material, where it plays a crucial role in the decomposition process. Its ability to break down complex organic compounds contributes to nutrient cycling within the ecosystem, making it an essential player in maintaining soil health and fertility. In particular, S. phaeolivaceus is often associated with forest biomes, where it can be found in the litter layer and rhizosphere of plants. Here, it engages in symbiotic relationships with various plant species, promoting plant growth by enhancing nutrient availability through its metabolic activities. This interaction not only benefits the plants but also supports the overall biodiversity of the forest ecosystem. Additionally, S. phaeolivaceus is known for its production of bioactive compounds, which can have antimicrobial properties. This characteristic allows it to compete effectively with other microorganisms in its habitat, thus influencing the microbial community structure. Its presence can also help suppress plant pathogens, further highlighting its role in ecosystem resilience. Overall, the ecological niche of Streptomyces phaeolivaceus is characterized by its adaptability to various terrestrial environments, its involvement in nutrient cycling, and its significant interactions with both plants and other microorganisms, making it a vital component of the biomes it inhabits.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Streptomyces phaeolivaceus is known for its significant contributions to various industrial applications, particularly in the fields of biotechnology, pharmaceutical development, and waste management. This actinobacterium is renowned for its ability to produce a wide range of bioactive compounds, including antibiotics, which are crucial in the development of new medications. For instance, it has been documented to produce compounds that exhibit antimicrobial properties, making it a valuable resource in the pharmaceutical industry for the discovery of new drugs. In the realm of biotechnology, Streptomyces phaeolivaceus is involved in fermentation processes that can lead to the production of secondary metabolites. These metabolites are not only important for their therapeutic effects but also play a role in agricultural applications as biopesticides and biofertilizers, promoting sustainable farming practices. Moreover, this microorganism has demonstrated potential in waste management through its ability to degrade complex organic materials. Its enzymatic activity allows it to break down pollutants in contaminated environments, contributing to biodegradation processes that help in the remediation of polluted sites. Additionally, Streptomyces phaeolivaceus is being explored for its role in biofuel production. The metabolic pathways utilized by this organism can be harnessed to convert biomass into biofuels, providing a renewable energy source while reducing reliance on fossil fuels. Overall, the diverse capabilities of Streptomyces phaeolivaceus make it a promising candidate for various industrial applications, particularly in enhancing sustainability and health outcomes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 10

LLM predicted phenotypes: 3

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	google/gemini-flash-1.5	meta-llama/llama-3-70b-instruct:nitro	mistralai/mistral-7b-instruct	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openchat/openchat-7b	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	google/gemini-pro	google/gemini-pro
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain variable ✗	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	true ✗	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 3 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	true	true
Host association	FALSE	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Plant pathogenicity	TRUE	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	tail	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	bacillus ✗	coccus ✗	coccus ✗	bacillus ✗	bacillus ✗

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