Acinetobacter lanii

General Information

Source: gpt-4o-2024-05-13

Acinetobacter lanii is a member of the genus Acinetobacter, which is known for its remarkable ability to survive in a variety of environments, including soil, water, and hospital settings. One of the most intriguing aspects of A. lanii is its potential for bioremediation. This organism has shown a capacity to degrade various pollutants, making it a valuable candidate for cleaning up contaminated environments. Additionally, A. lanii is of interest due to its antibiotic resistance mechanisms. Like other Acinetobacter species, it can harbor multiple resistance genes, which makes it a subject of study in the context of hospital-acquired infections and the development of new antimicrobial strategies. From a genetic perspective, A. lanii possesses a relatively large genome with a high degree of plasticity, allowing it to adapt to different environmental stresses. This adaptability is partly due to its ability to acquire and integrate foreign DNA, which contributes to its resilience and versatility. In summary, Acinetobacter lanii is a microorganism of significant interest due to its bioremediation potential, antibiotic resistance, and genomic adaptability, making it a valuable subject for both environmental and medical research.*

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter lanii

NCBI ID

2715163

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/011/578/285/GCA_011578285.1_ASM1157828v1

File for sequence-based predictions:
GCA_011578285.1_ASM1157828v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Acinetobacter lanii is a member of the genus Acinetobacter, which is known for its clinical significance, particularly in hospital settings. It is associated with a variety of infections, including pneumonia, bloodstream infections, and wound infections. Acinetobacter lanii can be particularly problematic in immunocompromised patients, where it may lead to severe complications due to its ability to thrive in diverse environments, including on skin and in hospital equipment. One of the most concerning aspects of Acinetobacter lanii is its potential for antimicrobial resistance. Many strains exhibit resistance to multiple classes of antibiotics, making treatment options limited and challenging. This resistance is often attributed to the presence of beta-lactamases and other resistance mechanisms that allow the organism to survive in the presence of antimicrobial agents. In terms of immune evasion, Acinetobacter lanii can alter its surface structures, which helps it evade detection and destruction by the host's immune system. This ability to modify its surface antigens contributes to its pathogenicity and complicates the management of infections it causes. While Acinetobacter lanii is not as widely studied as some other species within the Acinetobacter genus, its role in nosocomial infections and its resistance profiles underscore the need for ongoing surveillance and research. Understanding its clinical implications is crucial for developing effective treatment strategies and infection control measures in healthcare settings.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter lanii is a species of bacteria that is primarily associated with urban environments and hospital settings. This microorganism thrives in moist environments and is often found in soil, water, and hospital surfaces, where it can persist due to its ability to form biofilms. Its ecological niche is particularly significant in human-associated habitats, where it can be a part of the normal microbiota but also has the potential to act as an opportunistic pathogen, especially in immunocompromised individuals. In terms of its role in the ecosystem, Acinetobacter lanii contributes to the decomposition of organic matter and plays a part in nutrient cycling. It is known for its ability to degrade various pollutants, which makes it an important player in bioremediation efforts. Furthermore, this bacterium exhibits antibiotic resistance, which poses challenges in clinical settings and highlights its adaptability to antibiotic-rich environments. Overall, Acinetobacter lanii exemplifies the complex interactions within its biomes, showcasing both beneficial roles in ecosystem functioning and potential risks in healthcare-associated infections.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter lanii has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where A. lanii is utilized for its ability to degrade pollutants, making it a candidate for bioremediation processes. This organism can break down complex organic compounds, which is particularly useful in the treatment of contaminated water and soil, thus contributing to effective waste management strategies. In the realm of biofuel production, A. lanii has been studied for its capacity to metabolize various substrates, potentially leading to the production of bioethanol through fermentation. This process can convert agricultural waste into valuable biofuels, promoting sustainable energy solutions. Furthermore, A. lanii has demonstrated promising capabilities in pharmaceutical development. Its enzymatic activities can be harnessed for the production of bioactive compounds, which may serve as precursors for drug synthesis. The organism's ability to produce specific enzymes can facilitate enzyme production for various industrial applications, including the synthesis of pharmaceuticals and other valuable chemicals. Overall, Acinetobacter lanii represents a versatile microorganism with applications spanning biotechnology, waste management, biofuel production, and pharmaceutical development, showcasing its importance in modern industrial processes.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	perplexity/llama-3-sonar-small-32k-chat	mistralai/mixtral-8x7b-instruct:nitro	mistralai/mistral-7b-instruct	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	openai/gpt-4o	openai/gpt-4o	google/gemma-7b-it	google/gemma-7b-it	openchat/openchat-7b	openchat/openchat-7b
Motility	FALSE	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	facultatively anaerobic ✗	facultatively anaerobic ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	true	true	true	true	true	true	false	false	true	false	false	true	true	false	false	false	false	true	true	true	true	true	true	true	true
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗
Health association	N/A	true	true	true	true	true	true	true	true	false	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	N/A	false	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	gamma	N/A	gamma ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗

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