Acinetobacter geminorum

General Information

Acinetobacter geminorum is a member of the genus Acinetobacter, which is known for its remarkable ability to survive in a variety of environments, including soil, water, and hospital settings. One of the most intriguing aspects of A. geminorum is its potential role in bioremediation. This organism has been studied for its ability to degrade various pollutants, making it a valuable candidate for cleaning up contaminated environments. Another notable feature of A. geminorum is its genetic adaptability. The species possesses a versatile genome that allows it to acquire and exchange genetic material with other microorganisms. This genetic plasticity not only contributes to its survival in diverse habitats but also makes it a subject of interest in studies related to antibiotic resistance. Understanding the mechanisms behind its genetic adaptability could provide insights into combating antibiotic-resistant infections. Additionally, A. geminorum has been observed to produce a variety of enzymes that are of industrial interest. These enzymes have potential applications in biotechnology, including the production of biofuels and the synthesis of valuable chemical compounds. The organism's ability to produce these enzymes under different environmental conditions further underscores its versatility and potential utility in various industrial processes. In summary, Acinetobacter geminorum is a microorganism of significant interest due to its bioremediation capabilities, genetic adaptability, and industrial enzyme production. These characteristics make it a valuable subject for ongoing research in environmental science, microbiology, and biotechnology.

Acinetobacter geminorum is a fascinating member of the Acinetobacter genus, notable for its emerging role in clinical settings. This organism has garnered attention due to its resistance to multiple antibiotics, which poses significant challenges in treating infections, particularly in immunocompromised patients. Its ability to thrive in various environments, including hospital settings, makes it a critical focus for infection control and public health research. One of the unique aspects of A. geminorum is its genetic adaptability, which allows it to acquire resistance genes from other bacteria. This characteristic not only complicates treatment options but also highlights the importance of understanding its genetic mechanisms for developing effective therapeutic strategies. Furthermore, A. geminorum has been studied for its potential in bioremediation processes, as some strains exhibit the ability to degrade environmental pollutants. This duality of being both a pathogen and a potential environmental ally makes it a compelling subject for research in both medical and ecological fields. In summary, Acinetobacter geminorum stands out due to its clinical significance, antibiotic resistance, and potential applications in bioremediation, making it a valuable organism for ongoing scientific investigation.

Taxonomy

Superkingdom: Bacteria

Phylum: Pseudomonadota

Class: Gammaproteobacteria

Order: Moraxellales

Family: Moraxellaceae

Genus: Acinetobacter

Species: Acinetobacter geminorum

NCBI ID

2730922

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/013/009/345/GCA_013009345.1_ASM1300934v1

File for sequence-based predictions:
GCA_013009345.1_ASM1300934v1_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Acinetobacter geminorum is a member of the Acinetobacter genus, which is known for its clinical significance, particularly in hospital settings. It has been associated with various infections, including ventilator-associated pneumonia, bloodstream infections, and wound infections. This organism is of particular concern due to its ability to acquire and express antimicrobial resistance mechanisms, making it difficult to treat infections effectively. Reports indicate that A. geminorum can exhibit resistance to multiple classes of antibiotics, including beta-lactams, aminoglycosides, and fluoroquinolones, which complicates therapeutic options for affected patients. In terms of pathogenicity, A. geminorum can form biofilms, which enhance its survival on medical devices and contribute to persistent infections. Its ability to evade the immune response is partly attributed to its outer membrane structure, which can hinder the recognition by immune cells. Furthermore, outbreaks of A. geminorum have been documented in healthcare facilities, highlighting its role as a nosocomial pathogen. While A. geminorum is primarily recognized for its pathogenic potential, there is ongoing research into its ecological role and potential applications in biotechnology. However, its clinical implications remain a significant concern, particularly in immunocompromised patients or those with underlying health conditions.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Acinetobacter geminorum is a versatile bacterium commonly found in various habitat types that include both natural and anthropogenic environments. This microorganism is particularly associated with soil and water ecosystems, thriving in areas that are rich in organic matter and nutrients. Its presence is often noted in freshwater systems, where it can be found in sediments and biofilms, contributing to the microbial community dynamics in these habitats. In addition to its natural habitats, Acinetobacter geminorum is frequently isolated from hospital environments, where it can be a part of the microbial flora on surfaces and medical equipment. This association highlights its role in nosocomial infections, making it an important organism in the study of antibiotic resistance and public health. Ecologically, Acinetobacter geminorum plays a significant role in nutrient cycling, particularly in the degradation of organic compounds. It is known for its ability to utilize a wide range of carbon sources, which allows it to adapt to various environmental conditions. This metabolic flexibility enables it to thrive in polluted environments, where it can contribute to bioremediation efforts by breaking down harmful substances. Notably, Acinetobacter geminorum can engage in symbiotic relationships with other microorganisms, enhancing the overall resilience and functionality of microbial communities. Its interactions with other bacteria can lead to increased nutrient availability and improved ecosystem health, demonstrating its importance in maintaining ecological balance. Overall, the adaptability and ecological significance of Acinetobacter geminorum underscore its role in both natural and human-altered environments, making it a key player in various biomes.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Acinetobacter geminorum has shown significant potential in various industrial applications. One of the primary areas of interest is in biotechnology, where Acinetobacter geminorum is utilized for its ability to degrade a wide range of pollutants, making it valuable in biodegradation processes. This capability allows it to be employed in waste management, particularly in the treatment of contaminated soils and water, where it can break down harmful substances such as hydrocarbons and heavy metals. In the realm of biofuel production, Acinetobacter geminorum has been studied for its role in the fermentation of organic materials, which can lead to the generation of bioethanol and other biofuels. Its metabolic pathways are of interest for optimizing the conversion of biomass into energy, contributing to sustainable energy solutions. Furthermore, this microorganism has potential applications in pharmaceutical development. Its unique enzymatic activities can be harnessed for the production of valuable compounds, including antibiotics and other bioactive molecules. The ability of Acinetobacter geminorum to produce specific enzymes can be exploited in enzyme production processes, which are crucial for various biotechnological applications. Overall, Acinetobacter geminorum represents a versatile organism with promising applications across multiple industries, particularly in environmental biotechnology, renewable energy, and pharmaceuticals, showcasing its importance in advancing sustainable practices and innovative solutions.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-pro-1.5	microsoft/wizardlm-2-8x22b	openai/gpt-4o	perplexity/llama-3-sonar-small-32k-chat	meta-llama/llama-3-70b-instruct:nitro	google/gemma-7b-it	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	google/palm-2-chat-bison-32k	google/palm-2-chat-bison-32k	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	false ✓	false ✓	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain negative	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain negative ✓	N/A	gram stain variable ✗	N/A	gram stain negative ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	true	true	true	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	true	true	true	true	true	true	true	false	true	false	false	true	true	false	false	true	true	true	true	true	true	false	false	false	false
Biosafety level	biosafety level 2	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 1 ✗	biosafety level 1 ✗	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓	biosafety level 2 ✓
Health association	N/A	true	true	true	true	true	true	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	false	false
Host association	N/A	true	true	true	true	true	true	false	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	gamma	gamma	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓

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