Mycolicibacterium mengxianglii

General Information

Mycolicibacterium mengxianglii is a fascinating microorganism belonging to the genus Mycolicibacterium. This genus is known for its complex and unique cell wall structure, which includes mycolic acids, contributing to its resilience and distinctive characteristics. One of the most intriguing aspects of M. mengxianglii is its potential in bioremediation. This organism has shown promise in breaking down environmental pollutants, making it a valuable candidate for cleaning up contaminated sites. Additionally, Mycolicibacterium mengxianglii is of interest due to its potential applications in biotechnology. The metabolic pathways of this bacterium are being studied for their ability to produce valuable secondary metabolites, which could have applications in pharmaceuticals and industrial processes. From a research perspective, M. mengxianglii offers insights into the evolution and adaptation of mycobacteria. Its genetic makeup provides clues about the mechanisms these bacteria use to survive in diverse and often harsh environments. This makes it a model organism for studying mycobacterial physiology and pathogenesis. Overall, Mycolicibacterium mengxianglii stands out due to its environmental and biotechnological potential, as well as its contribution to our understanding of mycobacterial biology.

Mycolicibacterium mengxianglii is a species of actinobacteria that has garnered interest due to its unique biochemical properties and ecological significance. This microorganism is notable for its ability to produce mycolic acids, which are long-chain fatty acids that play a crucial role in the structural integrity of the cell wall. The presence of these mycolic acids contributes to the organism's resilience against environmental stressors, making it a fascinating subject for studies on microbial survival mechanisms. One of the most intriguing aspects of M. mengxianglii is its potential applications in biotechnology and medicine. The unique lipid composition of its cell wall may offer insights into the development of novel antibiotics or antimicrobial agents, particularly in the context of combating resistant strains of bacteria. Furthermore, the organism's metabolic pathways are of interest for bioremediation efforts, as it may possess the ability to degrade complex organic compounds in contaminated environments. Additionally, M. mengxianglii has been isolated from various environmental sources, indicating its adaptability and ecological role in nutrient cycling. This adaptability makes it a valuable model organism for studying microbial ecology and the interactions within microbial communities. The exploration of its genetic and metabolic capabilities could lead to advancements in our understanding of actinobacterial diversity and their potential uses in industrial applications. In summary, Mycolicibacterium mengxianglii stands out due to its unique biochemical characteristics, potential biotechnological applications, and ecological significance, making it a promising candidate for further research in microbiology and related fields.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Mycobacteriales

Family: Mycobacteriaceae

Genus: Mycolicibacterium

Species: Mycolicibacterium mengxianglii

NCBI ID

2736649

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/015/710/575/GCA_015710575.2_ASM1571057v2

File for sequence-based predictions:
GCA_015710575.2_ASM1571057v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The organism Mycolicibacterium mengxianglii is a member of the genus Mycolicibacterium, which has been associated with various clinical implications. This microorganism is known to be a potential pathogen, particularly in immunocompromised individuals. Infections caused by M. mengxianglii can lead to significant morbidity, especially in patients with underlying health conditions such as diabetes or those undergoing immunosuppressive therapy. The organism has been implicated in pulmonary infections and cutaneous lesions, highlighting its role in both respiratory and skin-related diseases. One of the notable features of M. mengxianglii is its ability to exhibit antimicrobial resistance, which poses challenges in treatment. Resistance mechanisms may include the production of enzymes that degrade antibiotics or alterations in cell wall permeability, making it difficult for standard antimicrobial therapies to be effective. This resistance underscores the importance of susceptibility testing in clinical settings to guide appropriate treatment strategies. In terms of immune evasion, M. mengxianglii may employ various strategies to avoid detection and destruction by the host's immune system. These strategies can include the modulation of host immune responses and the ability to survive within macrophages, which are key players in the immune defense against pathogens. While research on M. mengxianglii is still emerging, its potential role in outbreaks and its clinical significance in specific populations warrant further investigation. Understanding the pathogenic mechanisms and clinical implications of this organism is crucial for developing effective prevention and treatment strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Mycolicibacterium mengxianglii is a species of bacterium that is primarily associated with soil environments and aquatic habitats. This microorganism thrives in nutrient-rich substrates, often found in areas with high organic matter content. Its ecological niche is characterized by the ability to degrade complex organic compounds, which plays a crucial role in nutrient cycling within these biomes. Soil Biomes: In terrestrial ecosystems, Mycolicibacterium mengxianglii contributes to the breakdown of organic materials, facilitating the release of nutrients back into the soil. This process is essential for maintaining soil health and fertility, supporting plant growth and overall ecosystem productivity. The bacterium often interacts with other soil microorganisms, forming a complex web of relationships that enhance soil structure and function. Aquatic Environments: In freshwater systems, Mycolicibacterium mengxianglii can be found in sediments and biofilms, where it participates in the decomposition of organic matter. Its presence in these environments is vital for the maintenance of water quality, as it helps in the breakdown of pollutants and organic waste. The bacterium may also engage in symbiotic relationships with other microorganisms, contributing to the stability and resilience of aquatic ecosystems. Overall, Mycolicibacterium mengxianglii plays a significant role in its associated biomes, acting as a decomposer and nutrient recycler, which is essential for the health and sustainability of both soil and aquatic environments.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Mycolicibacterium mengxianglii has shown promising potential in various industrial applications. One of the most notable areas is in biotechnology, where it can be utilized for fermentation processes to produce valuable metabolites. This organism is known for its ability to metabolize complex organic compounds, making it a candidate for the production of bioactive compounds that can be used in pharmaceuticals and nutraceuticals. In the realm of waste management, Mycolicibacterium mengxianglii has demonstrated capabilities in biodegradation, particularly in the breakdown of environmental pollutants. Its enzymatic activity allows it to degrade harmful substances, contributing to bioremediation efforts in contaminated sites. Furthermore, this microorganism is being explored for its role in biofuel production. Through fermentation, it can convert biomass into biofuels, providing a sustainable alternative to fossil fuels. The efficiency of Mycolicibacterium mengxianglii in utilizing various substrates enhances its potential in this sector. In pharmaceutical development, the unique metabolic pathways of Mycolicibacterium mengxianglii can lead to the discovery of novel antibiotics and other therapeutic agents. Its ability to produce specific enzymes can be harnessed for the synthesis of complex pharmaceutical compounds, making it a valuable organism in drug development. Overall, Mycolicibacterium mengxianglii represents a versatile microorganism with significant potential across multiple industries, particularly in biotechnology, waste management, biofuel production, and pharmaceutical development.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	meta-llama/llama-3-70b-instruct:nitro	google/gemini-pro	anthropic/claude-3-haiku:beta	perplexity/llama-3-sonar-small-32k-chat	openchat/openchat-7b	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openai/gpt-4	openai/gpt-4	google/gemini-flash-1.5	google/gemini-flash-1.5	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/gemma-7b-it	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	mistralai/mistral-7b-instruct
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain negative ✗	N/A	gram stain negative ✗	N/A	gram stain variable ✗
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	N/A	true	false	false	false	true	true	false	true	false	false	true	true	false	false	false	false	false	false	false	false	true	true	true	true	false	false	true	true
Biofilm formation	N/A	true	true	true	true	true	true	false	true	true	true	true	true	false	false	false	false	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	N/A	false	false	true	true	false	true	false	false	false	false	true	true	true	true	false	false	true	true	true	true	false	false	true	true	false	false	false	false
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗	biosafety level 3 ✗
Health association	N/A	false	true	true	true	true	true	false	true	false	false	true	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	false	false
Host association	TRUE	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	false ✗	false ✗
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	bacillus	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	bacillus ✓	coccus ✗	coccus ✗	bacillus ✓	bacillus ✓

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