Limosilactobacillus urinaemulieris

General Information

Limosilactobacillus urinaemulieris is a relatively recent addition to the genus Limosilactobacillus, which was reclassified from the genus Lactobacillus. This microorganism is particularly interesting due to its isolation from the human urinary tract, specifically from the urine of healthy women. This unique habitat suggests that L. urinaemulieris may play a role in the microbiota of the urinary system, potentially contributing to the maintenance of urinary health. One of the most compelling aspects of L. urinaemulieris is its potential probiotic properties. Like other members of the Limosilactobacillus genus, it may produce lactic acid, which can help maintain a low pH environment that is inhospitable to many pathogenic bacteria. This characteristic makes it a candidate for further research into urinary tract health and disease prevention. Additionally, L. urinaemulieris has been noted for its genomic features that align with other beneficial lactobacilli, including genes involved in the production of bacteriocins—antimicrobial peptides that can inhibit the growth of harmful bacteria. This antimicrobial activity could be harnessed for therapeutic applications or the development of novel antimicrobial agents. The study of L. urinaemulieris is still in its early stages, but its unique origin and potential health benefits make it a valuable subject for ongoing research. Understanding its role in the urinary microbiome could lead to new insights into microbial interactions within the human body and the development of targeted probiotic therapies.

Limosilactobacillus urinaemulieris is a fascinating species of lactic acid bacteria that has garnered attention for its unique ecological niche and potential health benefits. Originally isolated from the urine of a healthy individual, this organism is part of the normal microbiota and plays a role in maintaining urogenital health. Its ability to ferment carbohydrates into lactic acid contributes to the acidic environment of the urinary tract, which can inhibit the growth of pathogenic bacteria. One of the most interesting aspects of L. urinaemulieris is its potential application in probiotic therapies. Research has indicated that this species may help in the prevention of urinary tract infections (UTIs) by outcompeting harmful microorganisms and enhancing the overall microbial balance in the urogenital area. This makes it a valuable candidate for further studies aimed at developing probiotic supplements specifically targeting urinary health. Additionally, L. urinaemulieris is notable for its metabolic capabilities, particularly in the production of various bioactive compounds during fermentation. These compounds may have implications for gut health and overall well-being, making this organism a subject of interest in the fields of microbiology and nutrition. The exploration of its genetic and metabolic pathways could lead to new insights into the role of lactic acid bacteria in human health. In summary, Limosilactobacillus urinaemulieris stands out due to its unique isolation source, potential health benefits in urinary tract health, and its promising applications in probiotic research, making it a significant organism in the study of human-associated microbiomes.

Taxonomy

Superkingdom: Bacteria

Phylum: Bacillota

Class: Bacilli

Order: Lactobacillales

Family: Lactobacillaceae

Genus: Limosilactobacillus

Species: Limosilactobacillus urinaemulieris

NCBI ID

2742600

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/932/750/685/GCA_932750685.1_Limosilactobacillus_urinaemulieris_DSM106190

File for sequence-based predictions:
GCA_932750685.1_Limosilactobacillus_urinaemulieris_DSM106190_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The microorganism Limosilactobacillus urinaemulieris is a member of the Lactobacillus genus, which is known for its role in maintaining urological health and its potential implications in urinary tract infections (UTIs) and other related conditions. This organism is part of the normal flora in the human urinary tract and plays a crucial role in competitive exclusion of pathogenic bacteria, thereby contributing to the prevention of infections. Clinical studies have suggested that the presence of Limosilactobacillus urinaemulieris may be associated with a lower incidence of recurrent UTIs, particularly in women. Its ability to produce lactic acid helps to maintain a low pH in the urinary tract, which is unfavorable for the growth of many uropathogens. In terms of pathogenicity, while Limosilactobacillus urinaemulieris is generally considered non-pathogenic, there is a need for further research to fully understand its interactions with other microorganisms and its potential role in dysbiosis or imbalance of the microbiota, which can lead to various health issues. Regarding antimicrobial resistance, there is limited data on this specific organism; however, the Lactobacillus genus is generally known for its low levels of antibiotic resistance compared to other bacterial groups. This characteristic makes it a candidate for use in probiotic therapies, aimed at restoring healthy microbiota and preventing infections. Overall, Limosilactobacillus urinaemulieris holds promise in the field of urology and may be beneficial in developing new therapeutic strategies for managing urinary health, although more extensive clinical trials are necessary to establish its efficacy and safety in medical applications.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Limosilactobacillus urinaemulieris is a species of lactic acid bacteria primarily associated with the urinary tract microbiome of mammals, particularly in the context of the female reproductive system. This microorganism thrives in the urogenital environment, where it plays a crucial role in maintaining the health of the host by contributing to the microbial balance and preventing the overgrowth of pathogenic organisms. In this biome, L. urinaemulieris exhibits symbiotic relationships with other beneficial microorganisms, helping to form a protective barrier against infections. Its ability to produce lactic acid contributes to the acidic pH of the urine, which is essential for inhibiting the growth of harmful bacteria. Additionally, this species is often found in association with mucosal surfaces, where it can adhere to epithelial cells, further enhancing its protective role. The presence of L. urinaemulieris is indicative of a healthy microbiome, and its abundance can be influenced by factors such as diet, hormonal changes, and overall health. Overall, Limosilactobacillus urinaemulieris is a vital component of the urogenital microbiome, contributing to the host's health through its metabolic activities and interactions with other microbial inhabitants.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Limosilactobacillus urinaemulieris has shown potential in various industrial applications, particularly in the fields of biotechnology and waste management. This organism is known for its role in fermentation, where it can be utilized to produce lactic acid, a valuable compound in food preservation and the production of biodegradable plastics. The ability of Limosilactobacillus urinaemulieris to ferment sugars efficiently makes it a candidate for biofuel production, as it can convert biomass into ethanol through fermentation processes, contributing to renewable energy solutions. In the realm of pharmaceutical development, Limosilactobacillus urinaemulieris may be explored for its probiotic properties, which can enhance gut health and potentially lead to the development of functional foods or dietary supplements. Its enzymatic activity is also noteworthy, as it can produce enzymes that are beneficial in various biotechnological applications, including the breakdown of complex carbohydrates. Moreover, this microorganism has implications in waste treatment, where it can aid in the biodegradation of organic waste, thus contributing to more sustainable waste management practices. The utilization of Limosilactobacillus urinaemulieris in these processes highlights its versatility and importance in advancing industrial biotechnology and environmental sustainability.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 9

LLM predicted phenotypes: 4

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/gemini-flash-1.5	mistralai/mixtral-8x7b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	google/palm-2-chat-bison-32k	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	microsoft/phi-3-mini-128k-instruct	mistralai/mistral-7b-instruct	google/gemini-pro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4	openai/gpt-4	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	openchat/openchat-7b	openchat/openchat-7b	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b
Motility	FALSE	false ✓	false ✓	false ✓	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	gram stain negative ✗	gram stain negative ✗	gram stain negative ✗	gram stain variable ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	anaerobic	N/A	N/A	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	facultatively anaerobic ✗	facultatively anaerobic ✗	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biofilm formation	N/A	true	true	true	true	true	true	true	true	false	true	true	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	true	true	true	true	true	true	true	false	false	true	false	false	true	true	true	true	true	true	true	true	true	true	true	true	true	true
Host association	TRUE	true ✓	true ✓	true ✓	true ✓	false ✗	true ✓	false ✗	false ✗	true ✓	true ✓	false ✗	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Hemolysis	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	alpha	alpha	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	coccus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	coccus	bacillus	bacillus

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