Micromonospora ferruginea

General Information

Micromonospora ferruginea is a fascinating microorganism belonging to the genus Micromonospora, which is well-known for its prolific production of bioactive compounds. One of the most intriguing aspects of M. ferruginea is its ability to produce a variety of secondary metabolites, many of which have significant pharmaceutical potential. These metabolites include antibiotics, antifungals, and antitumor agents, making this species particularly valuable in the field of drug discovery and development. What sets Micromonospora ferruginea apart is its unique metabolic pathways that enable it to synthesize complex molecules with high specificity and potency. Researchers are especially interested in the genetic and enzymatic mechanisms underlying these pathways, as understanding them could lead to the development of new and more effective drugs. Another noteworthy characteristic of M. ferruginea is its ecological role. It is commonly found in soil and aquatic environments, where it contributes to the decomposition of organic matter and the cycling of nutrients. This ecological function not only highlights its importance in natural ecosystems but also suggests potential applications in bioremediation. In summary, Micromonospora ferruginea is a microorganism of significant interest due to its ability to produce a wide range of bioactive compounds, its unique metabolic capabilities, and its important ecological role. These attributes make it a valuable subject for ongoing research in microbiology, biotechnology, and environmental science.

Micromonospora ferruginea is a fascinating actinobacterium that has garnered attention due to its unique ecological niche and potential biotechnological applications. This microorganism is primarily isolated from soil and has been found in various environments, showcasing its adaptability and resilience. One of the most interesting aspects of M. ferruginea is its ability to produce a range of bioactive compounds, including antibiotics and other secondary metabolites, which are of significant interest in pharmaceutical research. The discovery of novel compounds from this species could lead to the development of new therapeutic agents, particularly in the fight against antibiotic-resistant bacteria. In addition to its antibiotic production, M. ferruginea is notable for its role in the degradation of complex organic materials, contributing to nutrient cycling in its natural habitat. This capability makes it a valuable organism for studies focused on bioremediation and environmental sustainability. Understanding the metabolic pathways and genetic mechanisms behind its degradation processes could provide insights into improving bioremediation strategies. Furthermore, the genetic and biochemical diversity within the Micromonospora genus, including M. ferruginea, presents opportunities for research into microbial ecology and evolution. Investigating the interactions between M. ferruginea and other microorganisms in its environment can enhance our understanding of microbial communities and their functions. Overall, Micromonospora ferruginea stands out as a promising candidate for further research in microbiology, biotechnology, and environmental science.

Taxonomy

Superkingdom: Bacteria

Phylum: Actinomycetota

Class: Actinomycetes

Order: Micromonosporales

Family: Micromonosporaceae

Genus: Micromonospora

Species: Micromonospora ferruginea

NCBI ID

2749844

Genome Info

FTP Path:
ftp.ncbi.nlm.nih.gov/genomes/all/GCA/013/694/245/GCA_013694245.2_ASM1369424v2

File for sequence-based predictions:
GCA_013694245.2_ASM1369424v2_genomic.fasta

Descriptions

Clinical Implications and Relevance

Source: gpt-4o-mini-2024-07-18

The actinobacterium Micromonospora ferruginea has garnered attention due to its antimicrobial properties and potential applications in medicine. This organism is known to produce a variety of bioactive compounds, including antibiotics, which can be effective against a range of pathogenic bacteria. Its role in human health is primarily linked to its ability to combat infections, particularly those caused by multidrug-resistant organisms. In terms of pathogenicity, Micromonospora ferruginea is not typically associated with human disease; however, its metabolites have been studied for their therapeutic potential. The organism's ability to produce secondary metabolites makes it a candidate for the development of new therapeutics and probiotics. Moreover, the study of Micromonospora ferruginea contributes to our understanding of immune evasion strategies employed by microorganisms, as its metabolites may influence host immune responses. While there are no well-documented outbreaks directly linked to this species, its relevance in the context of antimicrobial resistance highlights the need for ongoing research into its applications in combating resistant infections. Overall, Micromonospora ferruginea represents a promising area of study in the search for novel antimicrobial agents and therapeutic strategies.

Habitat and Ecological Niches

Source: gpt-4o-mini-2024-07-18

Micromonospora ferruginea is a filamentous bacterium commonly found in various terrestrial ecosystems and aquatic environments. This microorganism thrives particularly in soil and freshwater habitats, where it plays a crucial role in the decomposition of organic matter. Its ability to degrade complex organic compounds makes it an essential player in nutrient cycling within these biomes. In soil ecosystems, Micromonospora ferruginea contributes to the breakdown of plant materials, thus facilitating the release of nutrients back into the soil. This process not only enriches the soil but also supports the growth of other organisms, creating a dynamic and interconnected ecosystem. The bacterium often forms symbiotic relationships with various plants, enhancing their nutrient uptake and overall health. In freshwater environments, Micromonospora ferruginea can be found in sediments and biofilms, where it interacts with other microbial communities. Its presence is vital for maintaining the balance of microbial populations and contributes to the overall health of the aquatic ecosystem. The bacterium's ability to adapt to varying environmental conditions, such as changes in pH and temperature, allows it to thrive in diverse habitats. Overall, Micromonospora ferruginea exemplifies the intricate relationships within biomes, showcasing its role in nutrient cycling, symbiosis, and environmental adaptation.

Industrial Application

Source: gpt-4o-mini-2024-07-18

The microorganism Micromonospora ferruginea has shown significant potential in various industrial applications. One of the most notable areas is in biotechnology, where it is utilized for its ability to produce a range of bioactive compounds, including antibiotics. This capability is particularly valuable in the development of new pharmaceuticals, as M. ferruginea can be harnessed for fermentation processes that yield these important medicinal products. In the realm of waste management, Micromonospora ferruginea has demonstrated effectiveness in biodegradation processes. It can break down complex organic materials, making it useful in the treatment of industrial waste and in the bioremediation of contaminated environments. This ability to degrade pollutants contributes to cleaner ecosystems and supports sustainable waste management practices. Additionally, M. ferruginea has potential applications in biofuel production. Its metabolic pathways can be exploited to convert biomass into biofuels through fermentation, providing an alternative energy source that is more environmentally friendly compared to fossil fuels. Overall, the diverse capabilities of Micromonospora ferruginea in pharmaceutical development, waste management, and biofuel production highlight its importance in modern industrial processes, making it a valuable organism for future research and application.

Phenotypes and Predictions

The table shows the phenotypes and predictions. Cell colors indicate the class of the value. When literature-based data is available, a checkmark (✓) indicates a correct prediction, while an ✗ indicates an incorrect prediction.

Literature-based phenotypes: 8

LLM predicted phenotypes: 5

Phenotype	High-quality annotation	anthropic/claude-3.5-sonnet	google/palm-2-chat-bison-32k	google/gemini-flash-1.5	google/gemini-flash-1.5	mistralai/mistral-7b-instruct	perplexity/llama-3-sonar-small-32k-chat	google/gemma-7b-it	openchat/openchat-7b	microsoft/phi-3-mini-128k-instruct	mistralai/mixtral-8x7b-instruct:nitro	openai/gpt-3.5-turbo-0125	openai/gpt-3.5-turbo-0125	openai/gpt-4o	openai/gpt-4o	google/gemini-pro-1.5	google/gemini-pro-1.5	meta-llama/llama-3-8b-instruct:nitro	meta-llama/llama-3-8b-instruct:nitro	openai/gpt-4	openai/gpt-4	meta-llama/llama-3-70b-instruct:nitro	meta-llama/llama-3-70b-instruct:nitro	microsoft/wizardlm-2-8x22b	microsoft/wizardlm-2-8x22b	google/gemini-pro	google/gemini-pro	anthropic/claude-3-haiku:beta	anthropic/claude-3-haiku:beta
Motility	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Gram staining	gram stain positive	gram stain positive ✓	gram stain positive ✓	N/A	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain positive ✓	gram stain negative ✗	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓	N/A	gram stain positive ✓
Aerophilicity	aerobic	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	N/A	N/A	N/A	N/A	N/A	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerotolerant ✗	aerotolerant ✗	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	aerobic ✓	N/A	N/A
Extreme environment tolerance	FALSE	false ✓	false ✓	true ✗	true ✗	true ✗	true ✗	true ✗	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗	false ✓	false ✓	false ✓	false ✓	true ✗	true ✗
Biofilm formation	N/A	true	true	true	true	false	true	true	false	true	true	true	true	true	true	false	false	true	true	false	false	true	true	true	true	true	true	true	true
Animal pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Biosafety level	biosafety level 1	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 2 ✗	biosafety level 2 ✗	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓	biosafety level 1 ✓
Health association	N/A	false	true	true	true	false	true	false	false	false	true	false	false	false	false	false	false	false	false	true	true	true	true	true	true	true	true	true	true
Host association	N/A	false	false	true	true	true	true	false	false	false	true	false	false	false	false	false	false	false	false	false	false	true	true	false	false	false	false	false	false
Plant pathogenicity	FALSE	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	true ✗	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓	false ✓
Spore formation	TRUE	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	false ✗	false ✗	false ✗	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓	true ✓
Hemolysis	N/A	N/A	N/A	gamma	gamma	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
Cell shape	N/A	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	coccus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus	bacillus

Back to Search